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Results for “Mutation Abnormality”

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Showing 20 of 0 results

Testing effectiveness (Phase 2)Study completedNCT01580735
What this trial is testing

ARQ 197 Plus Erlotinib in Patient With Locally Advanced or Metastatic EGFR Mutation-positive Non-small-cell Lung Cancer

Who this might be right for
Non-small-cell Lung Cancer
Kyowa Kirin Co., Ltd. 40
Early research (Phase 1)WithdrawnNCT04602117
What this trial is testing

ISPY-P1.01:Evaluating the Safety of Weekly Paclitaxel With Trastuzumab Duocarmazine (SYD985) in Patients With Metastatic Cancer

Who this might be right for
HER2-positive Breast CancerHER2 LowSYD-985+24 more
QuantumLeap Healthcare Collaborative
Testing effectiveness (Phase 2)Looking for participantsNCT05528458
What this trial is testing

Osimertinib to Suppress the Progression of Remaining GGN for EGFR Mutation-positive Stage IB-IIIA Lung Adenocarcinoma

Who this might be right for
Lung Adenocarcinoma
Samsung Medical Center 59
Large-scale testing (Phase 3)Active Not RecruitingNCT04776655
What this trial is testing

Study in mCRC Patients RAS/BRAF wt Tissue and RAS Mutated LIquid BIopsy to Compare FOLFIRI Plus CetuxiMAb or BevacizumaB

Who this might be right for
Colorectal CancerMetastatic Colorectal CancerRAS Mutation
Azienda USL Reggio Emilia - IRCCS 280
Not applicableStudy completedNCT05456048
What this trial is testing

Influence of Molecular Abnormalities on Response of VAH vs. VEN+HMA in RR-AML

Who this might be right for
Relapsed Acute Myeloid LeukemiaRefractory Acute Myeloid LeukemiaGene Abnormality+1 more
Nanfang Hospital, Southern Medical University 231
Testing effectiveness (Phase 2)Active Not RecruitingNCT04917809
What this trial is testing

Oral Erdafitinib in People With Recurrent Non-Invasive Bladder Cancer

Who this might be right for
Bladder CancerRecurrent Bladder CancerFGFR3 Gene Mutation
Memorial Sloan Kettering Cancer Center 20
Post-approval studies (Phase 4)Not Yet RecruitingNCT06893354
What this trial is testing

Explore the Mechanisms Underlying Disease Resistance and Potential Primary Resistance Mechanism of Induction Therapy Lorlatinib in Resectable Non-small Cell Lung Cancer (NSCLC) Harboring ALK Positive Mutation Revealed by Single-cell RNA Sequencing and Spatial Transcriptomics

Who this might be right for
NSCLC
The First Affiliated Hospital of Guangzhou Medical University 20
Early research (Phase 1)Looking for participantsNCT04260022
What this trial is testing

Study of HQP1351 in Subjects With Refractory CML and Ph+ ALL

Who this might be right for
Leukemia, Myeloid, ChronicMyeloid LeukemiaChronic Myeloid Leukemia+2 more
Ascentage Pharma Group Inc. 242
Large-scale testing (Phase 3)UnknownNCT04855045
What this trial is testing

An Open-label, Dose Escalation and Double-masked, Randomized, Controlled Trial Evaluating Safety and Tolerability of Sepofarsen in Children (<8 Years of Age) With LCA10 Caused by Mutations in the CEP290 Gene.

Who this might be right for
Leber Congenital Amaurosis 10BlindnessLeber Congenital Amaurosis+8 more
ProQR Therapeutics 15
Testing effectiveness (Phase 2)Active Not RecruitingNCT05194995
What this trial is testing

JAB-21822 in Combination With Cetuximab in Patients With Advanced CRC and Other Solid Tumors With KRAS G12C Mutation

Who this might be right for
Advanced Colorectal CancerSmall Intestinal CancerAppendiceal Cancer
Allist Pharmaceuticals, Inc. 48
Testing effectiveness (Phase 2)Study completedNCT04677595
What this trial is testing

Study of Capmatinib in Chinese Adult Patients With Advanced Non-small Cell Lung Cancer Harboring MET Exon 14 Skipping Mutation

Who this might be right for
Non-Small Cell Lung Cancer (NSCLC)
Novartis Pharmaceuticals 36
Not applicableStudy completedNCT01783795
What this trial is testing

Dent Disease Mutation Genotyping

Who this might be right for
Dent Disease
Mayo Clinic 180
Not applicableUnknownNCT06409039
What this trial is testing

POLE-END REAL LIFE: Endometrial Cancer Early Stages I-II and Advanced Stages III and IV Evaluation of POLE as a Prognostic Factor. Participants Are Women >= 18 Years Old, With the Pole Mutation

Who this might be right for
Endometrial Neoplasms
Azienda Ulss 2 Marca Trevigiana 80
Not applicableUnknownNCT05370677
What this trial is testing

The Prevelence of IVS 1-6 (T-C) [HBB:c.92 +6 T-C] Gene Mutation in Suspected Cases of β Thalassemia in Assiut University Hospitals

Who this might be right for
Beta-Thalassemia
Assiut University 141
Not applicableLooking for participantsNCT06536257
What this trial is testing

Personalised Immunotherapy Platform

Who this might be right for
MelanomaCutaneous Squamous Cell CarcinomaBasal Cell Carcinoma+2 more
Melanoma Institute Australia 1,000
Not applicableUnknownNCT04997629
What this trial is testing

Gene Biobank of Sports Injuries

Who this might be right for
Gene InsertionsGene Deletion
Peking University Third Hospital 10,000
Testing effectiveness (Phase 2)Active Not RecruitingNCT04117945
What this trial is testing

Regorafenib, With Cetuximab or Panitumumab, for the Treatment of Unresectable, Locally Advanced, or Metastatic Colorectal Cancer

Who this might be right for
BRAF V600E NegativeKRAS Gene Mutation NegativeLocally Advanced Unresectable Colorectal Adenocarcinoma+10 more
Academic and Community Cancer Research United 22
Large-scale testing (Phase 3)Study completedNCT02394795
What this trial is testing

Panitumumab and RAS, Diagnostically-useful Gene Mutation for mCRC

Who this might be right for
Colorectal Cancer
Takeda 823
Early research (Phase 1)Ended earlyNCT01907802
What this trial is testing

Dabrafenib in Treating Patients With Solid Tumors and Kidney or Liver Dysfunction

Who this might be right for
BRAF Gene MutationHepatic ComplicationRenal Failure+1 more
National Cancer Institute (NCI) 8
Not applicableLooking for participantsNCT03206190
What this trial is testing

The preSPG4 Study - Studying the Prodromal and Early Phase of SPG4

Who this might be right for
Hereditary Spastic ParaplegiaHereditary, Spastic Paraplegia, Autosomal Dominant
University Hospital Tuebingen 200
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