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Results for “Mutations”

4,183 trials

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Enrolling by Invitation

Showing 20 of 4,183 results

Testing effectiveness (Phase 2)UnknownNCT05005468
What this trial is testing

A Phase II Trial of Camrelizumab Combined With Famitinib for Adjuvant Treatment of Stage II-IIIA NSCLC.

Who this might be right for
NSCLC
Shanghai Chest Hospital 61
Testing effectiveness (Phase 2)Looking for participantsNCT06728410
What this trial is testing

A Phase II Study of Pemigatinib Plus Durvalumab in Previously Treated Advanced Intrahepatic Cholangiocarcinoma Patients With FGFR-2 Fusion or Rearrangement

Who this might be right for
Intrahepatic CholangiocarcinomaFGFR2 Gene RearrangementFGFR2 Gene Mutation
Mehmet Akce 38
Not applicableStudy completedNCT01085227
What this trial is testing

Clinical, Molecular and by Neuroimaging of LRRK2 Mutations

Who this might be right for
Parkinson's Disease
Institut National de la Santé Et de la Recherche Médicale, France 50
Testing effectiveness (Phase 2)Study completedNCT04042558
What this trial is testing

A Study Evaluating Platinum-Pemetrexed-Atezolizumab (+/-Bevacizumab) for Patients With Stage IIIB/IV Non-squamous Non-small Cell Lung Cancer With EGFR Mutations, ALK Rearrangement or ROS1 Fusion Progressing After Targeted Therapies

Who this might be right for
NSCLC Stage IIIBNSCLC Stage IVEGFR Gene Mutation+2 more
Centre Francois Baclesse 150
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07360743
What this trial is testing

Immunotherapy Without Chemotherapy for Advanced Lung Cancer Patients With High PD-L1 Levels

Who this might be right for
Non Small Cell Lung Cancer (Squamous or Non Squamous)
UNICANCER 275
Large-scale testing (Phase 3)UnknownNCT03203590
What this trial is testing

Clinical Trial of Neoadjuvant Targeted Treatment to NSCLC Patients

Who this might be right for
2-year Disease-Free Survival
Sun Yat-sen University 590
Large-scale testing (Phase 3)UnknownNCT02001896
What this trial is testing

Erlotinib Intercalated With Chemotherapy Versus Erlotinib as First Line Treatment in Stage IIIB/IV NSCLC Patients With EGFR Mutation

Who this might be right for
Non-Small Cell Lung Cancer
Xinjiang Medical University 60
Not applicableLooking for participantsNCT03564561
What this trial is testing

Natural History of Pompe Disease

Who this might be right for
Glycogen Storage Disease Type II, Adult
Assistance Publique - Hôpitaux de Paris 20
Not applicableEnrolling By InvitationNCT07307469
What this trial is testing

Compassionate Administration of ZVS101e Injection for Extended Treatment

Who this might be right for
Patients With Bietti Crystalline Corneoretinal Dystrophy (Carrying Biallelic CYP4V2 Mutations)
Chigenovo Co., Ltd 32
Testing effectiveness (Phase 2)UnknownNCT04692740
What this trial is testing

Chlorambucil in Metastatic PDAC Patients Bearing a Germ Line DNA Defects Repair Mutations (SALE Trial)

Who this might be right for
Pancreatic Ductal Adenocarcinoma
Michele Reni 20
Early research (Phase 1)Study completedNCT01969643
What this trial is testing

A Safety Study of SGN-LIV1A in Breast Cancer Patients

Who this might be right for
HER2 Positive Breast NeoplasmsHormone Receptor Positive Breast NeoplasmsTriple Negative Breast Neoplasms+1 more
Seagen Inc. 290
Not applicableUnknownNCT05411276
What this trial is testing

A Real-World Study of Pyrotinib Maleate in the Treatment of Advanced/Metastatic Non-Small Cell Lung Cancer With Rare Mutations in HER2

Who this might be right for
HER2 Mutant Non-small Cell Lung Cancer
Beijing Chest Hospital 15
Testing effectiveness (Phase 2)Ended earlyNCT04310397
What this trial is testing

Dabrafenib, Trametinib, and Spartalizumab for the Treatment of BRAF V600E or V600K Mutation Positive Stage IIIB/C/D Melanoma

Who this might be right for
Pathologic Stage IIIB Cutaneous Melanoma AJCC v8Pathologic Stage IIIC Cutaneous Melanoma AJCC v8Pathologic Stage IIID Cutaneous Melanoma AJCC v8
M.D. Anderson Cancer Center 4
Not applicableStudy completedNCT02285361
What this trial is testing

GIOTRIF rPMS in Korean Patients With NSCLC

Who this might be right for
Carcinoma, Non-Small-Cell Lung
Boehringer Ingelheim 1,272
Testing effectiveness (Phase 2)Study completedNCT02676843
What this trial is testing

Tau PET Imaging With 18F-AV-1451 in Subjects With MAPT Mutations

Who this might be right for
Frontotemporal Lobar Degeneration (FTLD)Frontotemporal Dementia (FTD)Tauopathies
Columbia University 7
Testing effectiveness (Phase 2)WithdrawnNCT02965417
What this trial is testing

Sym004 in Metastatic Colorectal Cancer and ECD-EGFR Patients

Who this might be right for
Metastatic Colorectal Cancer
Symphogen A/S
Testing effectiveness (Phase 2)Active Not RecruitingNCT05379946
What this trial is testing

Study to Evaluate D-1553 in Combination With IN10018 in Subjects With Solid Tumors

Who this might be right for
Solid Tumor
InventisBio Co., Ltd 92
Testing effectiveness (Phase 2)UnknownNCT03646968
What this trial is testing

Study of Anlotinib Combined With Docetaxel in Non-Driver Mutation Non-squamous NSCLC: the Save Study

Who this might be right for
Non-Squamous Non Small Cell Lung Cancer
Yongchang Zhang 43
Post-approval studies (Phase 4)Ended earlyNCT01683188
What this trial is testing

HD IL-2 + Vemurafenib in Patients With BRAF Mutation Positive Metastatic Melanoma

Who this might be right for
Metastatic Melanoma
Clinigen, Inc. 53
Testing effectiveness (Phase 2)UnknownNCT02681562
What this trial is testing

Olaparib in Locally Advanced ER, PgR and HER2 Negative (Triple Negative) and in Locally Advanced Germline BRCA Mutation-positive Breast Cancer Patients

Who this might be right for
Breast CancerTriple Negative Breast Cancer
Istituti Ospitalieri di Cremona 45
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