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Results for “Myelodysplastic/Myeloproliferative Neoplasm Overlap Syndrome”

15 trials

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Showing 15 of 15 results

Early research (Phase 1)Active Not RecruitingNCT04279847
What this trial is testing

Safety and Tolerability Study of INCB057643 in Participants With Myelofibrosis and Other Advanced Myeloid Neoplasms

Who this might be right for
MyelofibrosisMyelodysplastic SyndromeMyelodysplastic/Myeloproliferative Neoplasm Overlap Syndrome+4 more
Incyte Corporation 140
Not applicableEnded earlyNCT01688011
What this trial is testing

Connect® Myeloid Disease Registry

Who this might be right for
Primary MyelofibrosisMyelodysplastic SyndromesLeukemia, Myeloid, Acute
Celgene 2,013
Early research (Phase 1)Study completedNCT05665530
What this trial is testing

PRT2527 as Monotherapy and in Combination With Zanubrutinib or Venetoclax in Participants With R/R Hematologic Malignancies

Who this might be right for
Aggressive B-Cell Non-Hodgkin's Lymphoma (NHL)Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)Mantle Cell Lymphoma (MCL)+9 more
Prelude Therapeutics 86
Very early researchLooking for participantsNCT07071155
What this trial is testing

Momelotinib in Combination With Hypomethylating Agent for Chronic Phase Myelodysplastic Syndromes/Myeloproliferative Overlap Neoplasms and Chronic Neutrophilic Leukemia

Who this might be right for
Chronic Myelomonocytic LeukemiaMyelodysplastic SyndromesMyeloproliferative Overlap Neoplasms+1 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 18
Testing effectiveness (Phase 2)Looking for participantsNCT06523556
What this trial is testing

Axatilimab With or Without Azacitidine for the Treatment of Patients With Advanced Phase Myeloproliferative Neoplasms, Myeloproliferative Neoplasm/Myelodysplastic Syndrome Overlap or High Risk Chronic Myelomonocytic Leukemia

Who this might be right for
Atypical Chronic Myeloid LeukemiaChronic Myelomonocytic LeukemiaMyelodysplastic/Myeloproliferative Neoplasm+5 more
Uma Borate 52
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07468916
What this trial is testing

Ropeginterferon Alfa-2b for the Treatment of Myelodysplastic Syndrome/Myeloproliferative Neoplasm Overlap Syndromes and Chronic Myelomonocytic Leukemia

Who this might be right for
Atypical Chronic Myeloid LeukemiaChronic Myelomonocytic LeukemiaMyelodysplastic/Myeloproliferative Neoplasm+2 more
Jonsson Comprehensive Cancer Center 35
Early research (Phase 1)Looking for participantsNCT06138587
What this trial is testing

Preemptive CIML NK Cell Therapy After Hematopoietic Stem Cell Transplantation

Who this might be right for
Acute Myeloid LeukemiaLeukemiaLeukemia, Myeloid+3 more
Dana-Farber Cancer Institute 15
Testing effectiveness (Phase 2)Active Not RecruitingNCT04761770
What this trial is testing

Study of a Geriatric Assessment to Plan a Treatment Approach for Older People With Various Blood Disorders

Who this might be right for
Myelodysplastic SyndromeMyeloproliferative NeoplasmsChronic Myelomonocytic Leukemia+2 more
Memorial Sloan Kettering Cancer Center 33
Testing effectiveness (Phase 2)Enrolling By InvitationNCT06664970
What this trial is testing

Study on the Treatment of MDS/MPN Overlap Syndrome With AZA or Rux Combined With Selinexor

Who this might be right for
MDS
Peking Union Medical College Hospital 39
Early research (Phase 1)Looking for participantsNCT05549661
What this trial is testing

Onvansertib for the Treatment of Recurrent or Refractory Chronic Myelomonocytic Leukemia and Myelodysplastic Syndrome/MPN Overlap Neoplasms

Who this might be right for
Recurrent Chronic Myelomonocytic LeukemiaRefractory Chronic Myelomonocytic LeukemiaMyelodysplastic/Myeloproliferative Neoplasm, Not Otherwise Specified+3 more
Mayo Clinic 25
Not applicableLooking for participantsNCT07143669
What this trial is testing

Screening Study for KIT D816V Mutated Mast Cell Disease in Select Populations

Who this might be right for
Clonal Mast Cell DiseaseKIT D816V MutationSuspected KITD816V Mutated Clonal Mast Cell Disease
Blueprint Medicines Corporation 450
Testing effectiveness (Phase 2)Study completedNCT00274820
What this trial is testing

Arsenic Trioxide, Ascorbic Acid, Dexamethasone, and Thalidomide in Myelofibrosis/Myeloproliferative Disorder

Who this might be right for
Chronic Myeloproliferative DisordersLeukemiaMyelodysplastic Syndromes+1 more
Case Comprehensive Cancer Center 15
Testing effectiveness (Phase 2)WithdrawnNCT05927012
What this trial is testing

Evaluate the Safety and Preliminary Efficacy of a Response-guided Dose Titration of KER-047 in the Treatment of Functional IDA (Iron Deficiency Anemia).

Who this might be right for
Iron Deficiency Anemia
Keros Therapeutics, Inc.
Early research (Phase 1)Active Not RecruitingNCT03613532
What this trial is testing

Venetoclax Added to Fludarabine + Busulfan Prior to Transplant and to Maintenance Therapy for AML, MDS, and MDS/MPN

Who this might be right for
Acute Myeloid Leukemia (AML)Myelodysplastic Syndrome (MDS)Chronic Myelomonocytic Leukemia (CMML)+2 more
Jacqueline Garcia, MD 102
Testing effectiveness (Phase 2)Looking for participantsNCT07228624
What this trial is testing

Ruxolitinib Before, During and After Hematopoietic Cell Transplant in Older Patients With Myelofibrosis and Myelodysplastic Syndrome/Myeloproliferative Neoplasm Overlap Syndromes

Who this might be right for
Myelodysplastic/Myeloproliferative NeoplasmPrimary MyelofibrosisSecondary Myelofibrosis
Fred Hutchinson Cancer Center 50