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Results for “Myelofibrosis (MF)”

128 trials

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Showing 20 of 128 results

Very early researchNot Yet RecruitingNCT06414681
What this trial is testing

Combination of Tagraxofusp with Pacritinib in Patients with Intermediate-1 or Higher Myelofibrosis, Who Have Had Prior Therapy with the Approved JAK Inhibitors or in Which Therapy with the Approved JAK Inhibitors is Not Appropriate, Contraindicated or Declined

Who this might be right for
Myelofibrosis，MF
University of Kansas Medical Center 20
Early research (Phase 1)Study completedNCT01317875
What this trial is testing

Study of the JAK Inhibitor Ruxolitinib Administered Orally to Patients With Primary Myelofibrosis (PMF), Post-Polycythemia Vera-Myelofibrosis (PPV-MF) or Post-Essential Thrombocythemia-Myelofibrosis (PET-MF)

Who this might be right for
Myelofibrosis
Incyte Corporation 69
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07394153
What this trial is testing

Pacritinib For Bone Marrow Fibrosis In Patients With Myelofibrosis Who Have Thrombocytopenia

Who this might be right for
Myelofibrosis，MF
Grupo Español de Enfermedades Mieloproliferativas Crónicas PH Negativas 30
Testing effectiveness (Phase 2)UnknownNCT01298934
What this trial is testing

LBH589 (Panobinostat) for the Treatment of Myelofibrosis

Who this might be right for
Primary MyelofibrosisPolycythemia Vera, Post-Polycythemic Myelofibrosis PhasePost-Essential Thrombocythemia Related Myelofibrosis
Ronald Hoffman 22
Testing effectiveness (Phase 2)Study completedNCT02515630
What this trial is testing

Momelotinib in Transfusion-Dependent Adults With Primary Myelofibrosis (PMF) or Post-polycythemia Vera or Post-essential Thrombocythemia Myelofibrosis (Post-PV/ET MF)

Who this might be right for
Primary Myelofibrosis (PMF)Post-polycythemia Vera (Post-PV) MyelofibrosisPostessential Thrombocythemia (Post-ET) Myelofibrosis
Sierra Oncology LLC - a GSK company 41
Testing effectiveness (Phase 2)Looking for participantsNCT05280509
What this trial is testing

Study of TL-895 Combined With Ruxolitinib in JAKi Treatment-Naïve MF Subjects and Subjects With MF Who Have a Suboptimal Response to Ruxolitinib

Who this might be right for
MyelofibrosisPrimary MyelofibrosisPost-PV MF+1 more
Telios Pharma, Inc. 70
Testing effectiveness (Phase 2)Active Not RecruitingNCT05393674
What this trial is testing

Fedratinib in Combination With Nivolumab

Who this might be right for
Primary MyelofibrosisSecondary Myelofibrosis
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest 30
Testing effectiveness (Phase 2)Ended earlyNCT02711137
What this trial is testing

Open-Label Safety and Tolerability Study of INCB057643 in Subjects With Advanced Malignancies

Who this might be right for
Solid Tumors
Incyte Corporation 137
Early research (Phase 1)Looking for participantsNCT05279001
What this trial is testing

A Safety and Tolerability Study of Jaktinib

Who this might be right for
Myelofibrosis
Suzhou Zelgen Biopharmaceuticals Co.,Ltd 26
Testing effectiveness (Phase 2)Active Not RecruitingNCT03441113
What this trial is testing

Extended Access of Momelotinib in Adults With Myelofibrosis

Who this might be right for
NeoplasmsPost-polycythemia Vera Myelofibrosis (Post-PV MF)Primary Myelofibrosis (PMF)+1 more
GlaxoSmithKline 237
Testing effectiveness (Phase 2)Ended earlyNCT02440685
What this trial is testing

Evaluate ASN002 In Relapsed/Refractory Lymphoma And Advanced Solid Tumors

Who this might be right for
Lymphoma, Large B-Cell, DiffuseLymphoma, Mantle-CellLymphoma, Follicular+18 more
Asana BioSciences 51
Testing effectiveness (Phase 2)Study completedNCT00494585
What this trial is testing

CEP-701 for PH-negative Myelofibrosis

Who this might be right for
LeukemiaMyelofibrosis
M.D. Anderson Cancer Center 27
Testing effectiveness (Phase 2)Study completedNCT04217993
What this trial is testing

Jaktinib for the Treatment of Ruxolitinib Intolerance of Myelofibrosis

Who this might be right for
Primary Myelofibrosis (PMF)Post-polycythemia Vera Myelofibrosis(Post-PV MF)Post-essential Thrombocythemia Myelofibrosis(Post-ET MF)
Suzhou Zelgen Biopharmaceuticals Co.,Ltd 51
Testing effectiveness (Phase 2)Active Not RecruitingNCT04679870
What this trial is testing

Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Oral GB2064 in Participants With Myelofibrosis

Who this might be right for
Myelofibrosis
Galecto Biotech AB 21
Early research (Phase 1)Not Yet RecruitingNCT07302776
What this trial is testing

TACrolimus Targeted Immunosuppression Cessation in ALlogeneic HCT

Who this might be right for
GVHDHematopoietic Cell Transplantation (HCT)Acute Myeloid Leukemia (AML)+4 more
Stanford University 50
Testing effectiveness (Phase 2)WithdrawnNCT04629651
What this trial is testing

Captopril Use on the Degree of Marrow Fibrosis in Bone Marrow Fibrosis/Myeloproliferative Neoplasms

Who this might be right for
Bone Marrow FibrosisMyeloproliferative Neoplasm
Case Comprehensive Cancer Center
Early research (Phase 1)Ended earlyNCT03373877
What this trial is testing

Evaluation of Ruxolitinib in Combination With PU-H71 for Treatment of Myelofibrosis

Who this might be right for
MyelofibrosisPrimary MyelofibrosisPost-polycythemia Vera Myelofibrosis+1 more
Samus Therapeutics, Inc. 4
Not applicableActive Not RecruitingNCT06798805
What this trial is testing

Unraveling the Role of Extracellular Vesicles-driven Senescence in Myeloproliferative Neoplasms

Who this might be right for
Essential Thrombocythemia (ET)Myelofibrosis (MF)Polycythemia Vera (PV)
IRCCS Azienda Ospedaliero-Universitaria di Bologna 110
Testing effectiveness (Phase 2)Looking for participantsNCT06122831
What this trial is testing

A Clinical Trial of TQ05105 Tablets Combined With TQB3617 Capsules in the Treatment of Myelofibrosis (MF)

Who this might be right for
Myelofibrosis
Chia Tai Tianqing Pharmaceutical Group Co., Ltd. 92
Testing effectiveness (Phase 2)Ended earlyNCT02712905
What this trial is testing

An Open-Label, Dose-Escalation/Dose-Expansion Safety Study of INCB059872 in Subjects With Advanced Malignancies

Who this might be right for
Solid Tumors and Hematologic Malignancy
Incyte Corporation 116
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