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Results for “Myeloproliferative Neoplasm (MDS/MPN)”

49 trials

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Showing 20 of 49 results

Not applicableNot Yet RecruitingNCT07561385
What this trial is testing

Dresden MDS Registry With an Accompanying Biomaterial Collection

Who this might be right for
MDS (Myelodysplastic Syndrome)MDS/Myeloproliferative Neoplasm (MPN) Overlap SyndromeCHIP+1 more
Technische Universität Dresden 500
Early research (Phase 1)Ended earlyNCT05107856
What this trial is testing

PRT1419 as Monotherapy or in Combination With Azacitidine or Venetoclax in R/R Myeloid or B-cell Malignancies

Who this might be right for
Acute Myeloid LeukemiaB-cell Non-Hodgkin LymphomaChronic Lymphocytic Leukemia+7 more
Prelude Therapeutics Incorporated 21
Early research (Phase 1)Ended earlyNCT02663518
What this trial is testing

A Trial of PF-07901800 (TTI-621) for Patients With Hematologic Malignancies and Selected Solid Tumors

Who this might be right for
Hematologic MalignanciesSolid Tumor
Pfizer 249
Testing effectiveness (Phase 2)Ended earlyNCT05005182
What this trial is testing

Luspatercept With or Without Hydroxyurea for the Treatment of Myelodysplastic/Myeloproliferative Neoplasms With Ring Sideroblasts and Thrombocytosis or Unclassifiable With Ring Sideroblasts

Who this might be right for
Myelodysplastic/Myeloproliferative Neoplasm With Ring Sideroblasts and Thrombocytosis, Not Otherwise SpecifiedMyelodysplastic/Myeloproliferative Neoplasm, Not Otherwise Specified
Mayo Clinic 3
Testing effectiveness (Phase 2)Looking for participantsNCT04771130
What this trial is testing

BGB-11417 in Participants With Myeloid Malignancies

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic SyndromesMyelodysplastic/Myeloproliferative Neoplasm
BeOne Medicines 260
Early research (Phase 1)Study completedNCT05665530
What this trial is testing

PRT2527 as Monotherapy and in Combination With Zanubrutinib or Venetoclax in Participants With R/R Hematologic Malignancies

Who this might be right for
Aggressive B-Cell Non-Hodgkin's Lymphoma (NHL)Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)Mantle Cell Lymphoma (MCL)+9 more
Prelude Therapeutics Incorporated 86
Testing effectiveness (Phase 2)Looking for participantsNCT06523556
What this trial is testing

Axatilimab With or Without Azacitidine for the Treatment of Patients With Advanced Phase Myeloproliferative Neoplasms, Myeloproliferative Neoplasm/Myelodysplastic Syndrome Overlap or High Risk Chronic Myelomonocytic Leukemia

Who this might be right for
Atypical Chronic Myeloid LeukemiaChronic Myelomonocytic LeukemiaMyelodysplastic/Myeloproliferative Neoplasm+5 more
Uma Borate 49
Testing effectiveness (Phase 2)Ended earlyNCT04866056
What this trial is testing

Jaktinib and Azacitidine In Treating Patients With MDS With MF or MDS/MPN With MF.

Who this might be right for
Myelodysplastic SyndromesMyeloproliferative NeoplasmsMyelofibrosis
Suzhou Zelgen Biopharmaceuticals Co.,Ltd 1
Not applicableLooking for participantsNCT07680868
What this trial is testing

Caris Chromoseq Data Collection

Who this might be right for
Acute Myeloid Leukemia (AML)Myelodysplastic (MDS) / Myeloproliferative (MPN) DiseasesMyelodysplatic Syndromes+1 more
Caris Science, Inc. 300
Not applicableEnded earlyNCT01688011
What this trial is testing

Connect® Myeloid Disease Registry

Who this might be right for
Primary MyelofibrosisMyelodysplastic SyndromesLeukemia, Myeloid, Acute
Celgene 2,013
Early research (Phase 1)Looking for participantsNCT05549661
What this trial is testing

Onvansertib for the Treatment of Recurrent or Refractory Chronic Myelomonocytic Leukemia and Myelodysplastic Syndrome/MPN Overlap Neoplasms

Who this might be right for
Recurrent Chronic Myelomonocytic LeukemiaRefractory Chronic Myelomonocytic LeukemiaMyelodysplastic/Myeloproliferative Neoplasm, Not Otherwise Specified+3 more
Mayo Clinic 25
Testing effectiveness (Phase 2)Ended earlyNCT02431260
What this trial is testing

An Open-Label, Dose-Escalation Study of INCB054329 in Patients With Advanced Malignancies

Who this might be right for
Solid Tumors and Hematologic Malignancy
Incyte Corporation 69
Large-scale testing (Phase 3)Looking for participantsNCT04064060
What this trial is testing

Evaluate Long-term Safety in Participants Who Have Participated in Other Luspatercept (ACE-536) Clinical Trials

Who this might be right for
Myelodysplastic Syndromes (MDS)Beta-thalassemiaMyeloproliferative Neoplasm(MPN)-Associated Myelofibrosis
Celgene 665
Testing effectiveness (Phase 2)Ended earlyNCT02711137
What this trial is testing

Open-Label Safety and Tolerability Study of INCB057643 in Subjects With Advanced Malignancies

Who this might be right for
Solid Tumors
Incyte Corporation 137
Not applicableNot Yet RecruitingNCT07108023
What this trial is testing

Hematological Disorders in EHPVO Patients

Who this might be right for
Extrahepatic Portal Vein Obstruction (EHPVO)ThrombophiliaMyeloproliferative Neoplasms (MPN)+5 more
Rahab Nady 115
Testing effectiveness (Phase 2)Active Not RecruitingNCT05732961
What this trial is testing

Luspatercept for Anemia in Lower Risk MDS or Non-proliferative MDS/MPN Neoplasms

Who this might be right for
Myelodysplastic SyndromesMyeloproliferative NeoplasmAnemia
H. Lee Moffitt Cancer Center and Research Institute 6
Early research (Phase 1)Active Not RecruitingNCT03613532
What this trial is testing

Venetoclax Added to Fludarabine + Busulfan Prior to Transplant and to Maintenance Therapy for AML, MDS, and MDS/MPN

Who this might be right for
Acute Myeloid Leukemia (AML)Myelodysplastic Syndrome (MDS)Chronic Myelomonocytic Leukemia (CMML)+2 more
Jacqueline Garcia, MD 102
Testing effectiveness (Phase 2)Study completedNCT03072043
What this trial is testing

Phase 1b/2 Safety and Efficacy of APR-246 w/Azacitidine for tx of TP53 Mutant Myeloid Neoplasms

Who this might be right for
Myelodysplastic SyndromeAcute Myeloid LeukemiaMyeloproliferative Neoplasm+1 more
H. Lee Moffitt Cancer Center and Research Institute 55
Testing effectiveness (Phase 2)Study completedNCT03238248
What this trial is testing

Pevonedistat and Azacitidine in MDS or MDS/MPN Patients Who Fail Primary Therapy With DNA Methyl Transferase Inhibitors

Who this might be right for
Myelodysplastic SyndromesMyeloproliferative Neoplasm
Vanderbilt-Ingram Cancer Center 71
Testing effectiveness (Phase 2)Looking for participantsNCT07710534
What this trial is testing

Metronomic Decitabine-Cedazuridine and Venetoclax in R/R AML, HR-MDS, HR/AP MPN

Who this might be right for
Relapsed / Refractory AMLHigh Risk Myelodysplastic SyndromeHigh Risk Myeloproliferative Neoplasms
Virginia Commonwealth University 40
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