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Results for “Myeloproliferative Neoplasm (MPN)”

108 trials

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Showing 20 of 108 results

Testing effectiveness (Phase 2)Study completedNCT03011372
What this trial is testing

Evaluate the Efficacy and Safety of Pemigatinib (INCB054828) in Subjects With Myeloid/Lymphoid Neoplasms With FGFR1 Rearrangement - (FIGHT-203)

Who this might be right for
MPN (Myeloproliferative Neoplasms)
Incyte Corporation 47
Not applicableNot Yet RecruitingNCT07349134
What this trial is testing

WELL-MPN: A Digital Lifestyle App for Patients With MPNs

Who this might be right for
Myeloproliferative Neoplasms (MPNs)
Brigham and Women's Hospital 75
Not applicableStudy completedNCT02953704
What this trial is testing

Myelofibrosis and Essential Thrombocythemia Observational Study (MOST)

Who this might be right for
MPN (Myeloproliferative Neoplasms)
Incyte Corporation 1,469
Early research (Phase 1)Active Not RecruitingNCT04041050
What this trial is testing

A Study Evaluating Safety and Tolerability, and Pharmacokinetics of Navitoclax Monotherapy and in Combination With Ruxolitinib in Participants With Myeloproliferative Neoplasm

Who this might be right for
Myeloproliferative Neoplasm
AbbVie 85
Not applicableNot Yet RecruitingNCT07561385
What this trial is testing

Dresden MDS Registry With an Accompanying Biomaterial Collection

Who this might be right for
MDS (Myelodysplastic Syndrome)MDS/Myeloproliferative Neoplasm (MPN) Overlap SyndromeCHIP+1 more
Technische Universität Dresden 500
Testing effectiveness (Phase 2)Study completedNCT01348490
What this trial is testing

Ruxolitinib (INCB018424) in Participants With Primary Myelofibrosis (PMF), Post Essential Thrombocythemia-myelofibrosis and Post Polycythemia Vera-myelofibrosis (PPV-MF)

Who this might be right for
MPN (Myeloproliferative Neoplasms)
Incyte Corporation 66
Early research (Phase 1)Ended earlyNCT05107856
What this trial is testing

PRT1419 as Monotherapy or in Combination With Azacitidine or Venetoclax in R/R Myeloid or B-cell Malignancies

Who this might be right for
Acute Myeloid LeukemiaB-cell Non-Hodgkin LymphomaChronic Lymphocytic Leukemia+7 more
Prelude Therapeutics Incorporated 21
Early research (Phase 1)Ended earlyNCT02663518
What this trial is testing

A Trial of PF-07901800 (TTI-621) for Patients With Hematologic Malignancies and Selected Solid Tumors

Who this might be right for
Hematologic MalignanciesSolid Tumor
Pfizer 249
Testing effectiveness (Phase 2)Study completedNCT03144687
What this trial is testing

Itacitinib in Combination With Low-Dose Ruxolitinib or Itacitinib Alone Following Ruxolitinib in Participants With Myelofibrosis

Who this might be right for
MPN (Myeloproliferative Neoplasms)
Incyte Corporation 23
Not applicableActive Not RecruitingNCT04378855
What this trial is testing

Patient-Reported Outcomes in PHiladelphia-nEgative Cytogenetic mYeloproliferative Neoplasms (PROPHECY).

Who this might be right for
Myeloproliferative Neoplasm
Gruppo Italiano Malattie EMatologiche dell'Adulto 572
Not applicableLooking for participantsNCT07590986
What this trial is testing

Identification of MPN-specific Antigens and Anti-MPN TCRs in Myeloproliferative Neoplasm

Who this might be right for
Myeloproliferative Neoplasm (MPN)Polycytemia VeraEssential Thrombocythemia (ET)+1 more
Université Catholique de Louvain 150
Not applicableLooking for participantsNCT07410247
What this trial is testing

MPN Childhood Registry

Who this might be right for
Childhood Myeloproliferative Neoplasms
University of Erlangen-Nürnberg Medical School 500
Large-scale testing (Phase 3)Looking for participantsNCT06740916
What this trial is testing

Long-term Efficacy of Once Daily Versus Twice Daily Aspirin in High-risk MPN Patients With Aspirin Resistance

Who this might be right for
Myeloproliferative Neoplasms (MPN)
Siriraj Hospital 240
Testing effectiveness (Phase 2)Ended earlyNCT05005182
What this trial is testing

Luspatercept With or Without Hydroxyurea for the Treatment of Myelodysplastic/Myeloproliferative Neoplasms With Ring Sideroblasts and Thrombocytosis or Unclassifiable With Ring Sideroblasts

Who this might be right for
Myelodysplastic/Myeloproliferative Neoplasm With Ring Sideroblasts and Thrombocytosis, Not Otherwise SpecifiedMyelodysplastic/Myeloproliferative Neoplasm, Not Otherwise Specified
Mayo Clinic 3
Testing effectiveness (Phase 2)Ended earlyNCT04113616
What this trial is testing

An Open-Label, Multicenter, Phase 1b/2 Study of the Safety and Efficacy of KRT-232 When Administered Alone and in Combination With Low-Dose Cytarabine (LDAC) or Decitabine in Patients With Acute Myeloid Leukemia (AML)

Who this might be right for
Relapsed or Refractory Acute Myeloid Leukemia (AML)Acute Myeloid Leukemia (AML), Secondary to Myeloproliferative Neoplasms (MPN)
Kartos Therapeutics, Inc. 70
Testing effectiveness (Phase 2)Looking for participantsNCT04771130
What this trial is testing

BGB-11417 in Participants With Myeloid Malignancies

Who this might be right for
Acute Myeloid LeukemiaMyelodysplastic SyndromesMyelodysplastic/Myeloproliferative Neoplasm
BeOne Medicines 260
Testing effectiveness (Phase 2)Looking for participantsNCT05835466
What this trial is testing

Reparixin in Patients With Myelofibrosis Myeloproliferative Neoplasms Research Consortium (MPN-RC 120)

Who this might be right for
Myelofibrosis (PMF)Post Essential Thrombocythemia Myelofibrosis (ET-MF)Post Polycythemia Vera Related Myelofibrosis (PV-MF)
Icahn School of Medicine at Mount Sinai 10
Early research (Phase 1)Study completedNCT05665530
What this trial is testing

PRT2527 as Monotherapy and in Combination With Zanubrutinib or Venetoclax in Participants With R/R Hematologic Malignancies

Who this might be right for
Aggressive B-Cell Non-Hodgkin's Lymphoma (NHL)Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)Mantle Cell Lymphoma (MCL)+9 more
Prelude Therapeutics Incorporated 86
Testing effectiveness (Phase 2)Looking for participantsNCT06523556
What this trial is testing

Axatilimab With or Without Azacitidine for the Treatment of Patients With Advanced Phase Myeloproliferative Neoplasms, Myeloproliferative Neoplasm/Myelodysplastic Syndrome Overlap or High Risk Chronic Myelomonocytic Leukemia

Who this might be right for
Atypical Chronic Myeloid LeukemiaChronic Myelomonocytic LeukemiaMyelodysplastic/Myeloproliferative Neoplasm+5 more
Uma Borate 49
Large-scale testing (Phase 3)UnknownNCT02611973
What this trial is testing

Hydroxyurea Versus Aspirin and Hydroxyurea in Essential Thrombocythemia

Who this might be right for
MPNEssential Thrombocythemia
Assistance Publique - Hôpitaux de Paris 2,250
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