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Results for “NOTCH1 Gene Mutation”

6 trials

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Showing 6 of 6 results

Not applicableUnknownNCT03971318
What this trial is testing

A Prospective Multicenters Clinical Cohort Study of Stratified Treatment of Chinese Children With LBL

Who this might be right for
Lymphoma, Non-HodgkinLymphoblastic Lymphoma, ChildhoodPTEN Loss+2 more
Sun Yat-sen University 300
Testing effectiveness (Phase 2)Looking for participantsNCT06846463
What this trial is testing

Zanubrutinib in Patients With DLBCL and MYD88 or NOTCH1 Mutation or CD5+

Who this might be right for
Diffuse Large B-cell LymphomaDLBCL - Diffuse Large B Cell Lymphoma
Virginia Commonwealth University 21
Testing effectiveness (Phase 2)Study completedNCT03204188
What this trial is testing

Ibrutinib, Fludarabine, and Pembrolizumab in High-Risk or Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Who this might be right for
B-Cell Chronic Lymphocytic LeukemiaB-Lymphocytic Leukemia, ChronicChronic Lymphocytic Leukemia+6 more
National Heart, Lung, and Blood Institute (NHLBI) 15
Testing effectiveness (Phase 2)Study completedNCT02337829
What this trial is testing

Acalabrutinib in Patients With Relapsed/Refractory and Treatment naïve Deletion 17p CLL/SLL

Who this might be right for
Chronic Lymphocytic LeukemiaSmall Lymphocytic Lymphoma
Acerta Pharma BV 48
Not applicableNot Yet RecruitingNCT07157579
What this trial is testing

Notch 1 Mutation in Chronic Lymphocytic Leukemia and Non-Hodgkin's Lymphoma Patient

Who this might be right for
Chronic Lymphocytic Leukemia (CLL)- Non-Hodgins's Lymphoma (NHL)
Sohag University 80
Testing effectiveness (Phase 2)Ended earlyNCT03740100
What this trial is testing

Single-arm Study With Bimiralisib in Patients With HNSCC Harboring NOTCH1 Loss of Function Mutations

Who this might be right for
HNSCC
M.D. Anderson Cancer Center 8