Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “NSCLC Brain Metastasis”

259 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 259 results

Large-scale testing (Phase 3)UnknownNCT00268684
What this trial is testing

Comparison Study of WBRT and SRS Alone Versus With Temozolomide or Erlotinib in Patients With Brain Metastases of NSCLC

Who this might be right for
Carcinoma, Non-Small-Cell LungNeoplasm Metastasis
Tel-Aviv Sourasky Medical Center 381
Testing effectiveness (Phase 2)Study completedNCT01657799
What this trial is testing

Comparison of Veliparib and Whole Brain Radiation Therapy (WBRT) Versus Placebo and WBRT in Adults With Brain Metastases From Non-Small Cell Lung Cancer

Who this might be right for
Brain Metastases From Non-small Cell Lung Cancer
AbbVie (prior sponsor, Abbott) 307
Testing effectiveness (Phase 2)Ended earlyNCT04964960
What this trial is testing

Pembro+Chemo in Brain Mets

Who this might be right for
Lung CancerLung Cancer MetastaticBrain Cancer+1 more
John L. Villano, MD, PhD 3
Testing effectiveness (Phase 2)Looking for participantsNCT05064280
What this trial is testing

Phase II Study of Pembrolizumab in Combination With Lenvatinib in Patients With TNBC, NSCLC, and Other Tumor Types and Brain Metastases

Who this might be right for
Brain MetastasesTumor
M.D. Anderson Cancer Center 104
Not applicableUnknownNCT03414944
What this trial is testing

Elective Simultaneous Modulated Accelerated Brain Radiation Therapy for NSCLCs With Limited Brain Metastases

Who this might be right for
Brain Metastases
Shandong Cancer Hospital and Institute 30
Testing effectiveness (Phase 2)WithdrawnNCT04650490
What this trial is testing

SRS Timing With Immune Checkpoint Inhibition in Patients With Untreated Brain Metastases From Non-small Cell Lung Cancer

Who this might be right for
Brain MetastasesNon Small Cell Lung Cancer
Duke University
Testing effectiveness (Phase 2)UnknownNCT04675008
What this trial is testing

Central Nervous System(CNS) Efficacy of Dacomitinib

Who this might be right for
Non Small Cell Lung CancerBrain Metastases
Samsung Medical Center 30
Large-scale testing (Phase 3)Study completedNCT05807893
What this trial is testing

Study to Evaluate the Safety and Efficacy of Serplulimab Plus Bevacizumab and Chemotherapy in NSCLC Patients With Brain Metastases

Who this might be right for
Non-small Cell Lung Cancer Stage IIBevacizumabImmunotherapy+1 more
Sun Yat-sen University 40
Testing effectiveness (Phase 2)WithdrawnNCT04889066
What this trial is testing

Durvalumab (MEDI4736) and Radiosurgery (fSRT Vs. PULSAR) for the Treatment of Non-Small Cell Lung Cancer Brain Metastases

Who this might be right for
Brain Metastases from Non-small Cell Lung Cancer
University of Texas Southwestern Medical Center
Large-scale testing (Phase 3)Looking for participantsNCT06970639
What this trial is testing

A Study Evaluating Furmonertinib Plus Platinum-based Doublet Chemotherapy Versus Osimertinib in Patients With Epidermal Growth Factor Receptor (EGFR) Sensitizing Mutation-Positive Non-squamous Non-Small Cell Lung Cancer (NSCLC) and Brain Metastases

Who this might be right for
NSCLC Patients With Brain Metastasis
Allist Pharmaceuticals, Inc. 380
Large-scale testing (Phase 3)Ended earlyNCT00096265
What this trial is testing

Radiation Therapy and Stereotactic Radiosurgery With or Without Temozolomide or Erlotinib in Treating Patients With Brain Metastases Secondary to Non-Small Cell Lung Cancer

Who this might be right for
Metastatic Malignant Neoplasm in the BrainRecurrent Non-Small Cell Lung CarcinomaStage IV Non-Small Cell Lung Cancer AJCC v7
National Cancer Institute (NCI) 126
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06684873
What this trial is testing

A Multicenter, Single-arm, Open-label Study Evaluating the Safety and Efficacy of AK112 Combined With Chemotherapy as First-line Treatment for Non-squamous NSCLC Patients With BRAIN Metastases and Negative Driver Genes (IVO BRAIN)

Who this might be right for
NSCLCBrain Metastasases
Sun Yat-sen University 55
Testing effectiveness (Phase 2)UnknownNCT04147728
What this trial is testing

Stereotactic Radiosurgery Combination With Anlotinib for Limited Brain Metastases With Perilesional Edema in NSCLC

Who this might be right for
Stereotactic Body Radiation Therapy
Peking University Third Hospital 50
Testing effectiveness (Phase 2)WithdrawnNCT01913067
What this trial is testing

Evaluation of Cabazitaxel in Patients With Brain Metastasis Secondary to Breast Cancer and NSCLC

Who this might be right for
Brain MetastasisBreast CancerNon Small Cell Lung Cancer
Jules Bordet Institute
Large-scale testing (Phase 3)Ended earlyNCT02162537
What this trial is testing

Therapeutic Strategies in Patients With Non-squamous Non-small Cell Lung Cancer With Brain Metastases

Who this might be right for
Non-small Cell Lung Cancer MetastaticNon-small Cell Lung CancerAdenocarcinoma of Lung Metastatic to Brain+1 more
Centre Hospitalier Intercommunal Creteil 95
Testing effectiveness (Phase 2)Study completedNCT01806675
What this trial is testing

18F-FPPRGD2 PET/CT or PET/MRI in Predicting Early Response in Patients With Cancer Receiving Anti-Angiogenesis Therapy

Who this might be right for
Adult Giant Cell GlioblastomaAdult GlioblastomaAdult Gliosarcoma+41 more
Sanjiv Sam Gambhir 25
Testing effectiveness (Phase 2)Study completedNCT01514877
What this trial is testing

Icotinib Combined With Whole Brain Radiotherapy in Treating Multiple Brain Metastases From Non-Small Cell Lung Cancer

Who this might be right for
Lung CancerMetastatic Cancer
Zhejiang Cancer Hospital 20
Testing effectiveness (Phase 2)Study completedNCT00227019
What this trial is testing

Phase 2 Trial of Bevacizumab in Combination With Pemetrexed

Who this might be right for
Non-small Cell Lung Cancer (NSCLC)Lung CancerNeoplasm Metastasis
Heather Wakelee 16
Large-scale testing (Phase 3)Study completedNCT00403065
What this trial is testing

Dexamethasone and Supportive Care With or Without Whole-Brain Radiation Therapy in Treating Patients With Non-Small Cell Lung Cancer That Has Spread to the Brain and Cannot Be Removed By Surgery

Who this might be right for
Lung CancerMetastatic Cancer
Medical Research Council 1,000
Early research (Phase 1)Study completedNCT05021328
What this trial is testing

Toripalimab Combined With Anlotinib and SBRT in Patients With Untreated Brain Metastases of Driven Gene-negative NSCLC

Who this might be right for
NSCLC
Hubei Cancer Hospital 13
Load More Results