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Results for “NY-ESO-1 Positive”

24 trials

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Showing 20 of 24 results

Early research (Phase 1)UnknownNCT04318964
What this trial is testing

TAEST16001 in the Treatment of Soft Tissue Sarcoma

Who this might be right for
Soft Tissue Sarcoma
Sun Yat-sen University 12
Early research (Phase 1)Ended earlyNCT04526509
What this trial is testing

Master Protocol to Assess Safety and Dose of First Time in Human Next Generation Engineered T Cells in NY-ESO-1 and/or LAGE-1a Positive Advanced Solid Tumors

Who this might be right for
Neoplasms
Adaptimmune 12
Testing effectiveness (Phase 2)Study completedNCT02992743
What this trial is testing

Letetresgene Autoleucel Engineered T Cells in NY-ESO-1 Positive Participants With Advanced Myxoid/ Round Cell Liposarcoma

Who this might be right for
Neoplasms
GlaxoSmithKline 23
Early research (Phase 1)Study completedNCT03450122
What this trial is testing

Modified T Cells, Chemotherapy, and Aldesleukin With or Without LV305 and CMB305 in Treating Participants With Advanced or Recurrent Sarcoma

Who this might be right for
HLA-A*0201 Positive Cells PresentNY-ESO-1 Positive Tumor Cells PresentRecurrent Myxoid Liposarcoma+1 more
M.D. Anderson Cancer Center 15
Very early researchNot Yet RecruitingNCT05648994
What this trial is testing

TCR-T Cells for the Treatment NY-ESO-1-positive Advanced Solid Tumors

Who this might be right for
Solid Tumors
Fujian Cancer Hospital 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT05993299
What this trial is testing

Study to Evaluate Safety and Antitumor Activity of Lete-Cel (GSK3377794) in HLA-A2+ Participants With NY-ESO-1 Positive Previously Untreated Advanced (Metastatic or Unresectable) Synovial Sarcoma and Myxoid/Round Cell Liposarcoma

Who this might be right for
Neoplasms
Adaptimmune 7
Early research (Phase 1)Ended earlyNCT05943990
What this trial is testing

Study of GSK3845097 in Previously Treated Participants With Advanced Synovial Sarcoma and Myxoid/Round Cell Liposarcoma

Who this might be right for
Neoplasms
Adaptimmune 5
Testing effectiveness (Phase 2)WithdrawnNCT03697824
What this trial is testing

Clinical Trial of Safety, Tolerability and Antitumor Activity of Genetically Engineered T Cells in Combination With Anti-Cancer Agents in Relapsed and Refractory Synovial Sarcoma Expressing New York Esophageal Antigen-1 (NY-ESO-1) and/or LAGE-1a

Who this might be right for
Neoplasms
GlaxoSmithKline
Large-scale testing (Phase 3)Looking for participantsNCT07174427
What this trial is testing

Multi-center Study of TBI-1301 (INN: Mipetresgene Autoleucel; Mip-cel) in Patients With NY-ESO-1 Positive Synovial Sarcoma

Who this might be right for
Synovial Sarcomas
Takara Bio Inc. 5
Testing effectiveness (Phase 2)Ended earlyNCT03709706
What this trial is testing

Pilot Immunotherapy Study With Letetresgene Autoleucel (Lete-cel, GSK3377794)T-cells in New York Esophageal Squamous Cell Carcinoma-1 (NY-ESO-1)/ LAGE-1a-positive Advanced Non-small Cell Lung Cancer (NSCLC) Either Alone or in Combination With Pembrolizumab

Who this might be right for
Neoplasms
GlaxoSmithKline 34
Early research (Phase 1)Study completedNCT01522820
What this trial is testing

Vaccine Therapy With or Without Sirolimus in Treating Patients With NY-ESO-1 Expressing Solid Tumors

Who this might be right for
Anaplastic AstrocytomaAnaplastic OligoastrocytomaAnaplastic Oligodendroglioma+62 more
Roswell Park Cancer Institute 18
Early research (Phase 1)Study completedNCT02588612
What this trial is testing

Letetresgene Autoleucel Engineered T Cells in NY-ESO -1 Positive Advanced Non-Small Cell Lung Cancer (NSCLC)

Who this might be right for
Neoplasms
GlaxoSmithKline 10
Testing effectiveness (Phase 2)Ended earlyNCT03515551
What this trial is testing

Safety and Efficacy of IMCnyeso in Advanced NY-ESO-1 and/or LAGE-1A Positive Cancers

Who this might be right for
Select Advanced Solid Tumors
Immunocore Ltd 29
Early research (Phase 1)Ended earlyNCT03168438
What this trial is testing

Letetresgene Autoleucel Engineered T Cells Alone and in Combination With Pembrolizumab in NY-ESO-1 Positive Multiple Myeloma

Who this might be right for
Neoplasms
GlaxoSmithKline 6
Early research (Phase 1)Ended earlyNCT03240861
What this trial is testing

Genetically Engineered PBMC and PBSC Expressing NY-ESO-1 TCR After a Myeloablative Conditioning Regimen to Treat Patients With Advanced Cancer

Who this might be right for
HLA-A*0201 Positive Cells PresentLocally Advanced Malignant NeoplasmNY-ESO-1 Positive+2 more
Jonsson Comprehensive Cancer Center 5
Very early researchEnded earlyNCT02774291
What this trial is testing

Anti-NY ESO-1 mTCR Peripheral Blood Lymphocytes

Who this might be right for
HLA-A2 Positive Cells PresentMetastatic Malignant NeoplasmMetastatic Malignant Neoplasm in the Brain
Albert Einstein College of Medicine 3
Early research (Phase 1)Looking for participantsNCT06942143
What this trial is testing

An Open-label, Phase I Clinical Trial of Super1 TCR-T in NY-ESO-1-positive Patients With Advanced Solid Tumors

Who this might be right for
SarcomaLung CancersMelanoma
Guangzhou FineImmune Biotechnology Co., LTD. 15
Testing effectiveness (Phase 2)Active Not RecruitingNCT03967223
What this trial is testing

Master Protocol to Assess the Safety and Antitumor Activity of Genetically Engineered T Cells in NY-ESO-1 and/or LAGE-1a Positive Solid Tumors

Who this might be right for
Neoplasms
Adaptimmune 103
Testing effectiveness (Phase 2)UnknownNCT05549921
What this trial is testing

Phase II Study of TAEST16001 in Soft Tissue Sarcoma

Who this might be right for
Soft Tissue Sarcoma
Sun Yat-sen University 70
Early research (Phase 1)Active Not RecruitingNCT02869217
What this trial is testing

Study of TBI-1301 (NY-ESO-1 Specific TCR Gene Transduced Autologous T Lymphocytes) in Patients With Solid Tumors

Who this might be right for
NY-ESO-1 Expressing Solid Tumors in HLA-A2 Positive PatientsSynovial SarcomaMelanoma+5 more
University Health Network, Toronto 22
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