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Results for “Natural Killer Cell Malignancies”

377 trials

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Showing 20 of 377 results

Early research (Phase 1)Study completedNCT00076180
What this trial is testing

Hu-Mik-beta1 to Treat T-Cell Large Granular Lymphocytic Leukemia

Who this might be right for
T-Cell Large Granular Lymphocytic LeukemiaLeukemia, T-Cell Large Granular Lymphocytic
National Cancer Institute (NCI) 9
Early research (Phase 1)Ended earlyNCT05712278
What this trial is testing

Investigate Use of Off-the-shelf Natural Killer (NK) Cells (SAR445419) in Relapsed/Refractory Acute Myeloid Leukemia

Who this might be right for
Acute Myeloid Leukaemia
Sanofi 7
Large-scale testing (Phase 3)UnknownNCT00846157
What this trial is testing

Biocell Natural Killer Mixture in Diffuse Large B Cell Lymphoma (DLBCL) Patients

Who this might be right for
Diffuse Large B-cell Lymphoma
NKBio Co.Ltd. 276
Testing effectiveness (Phase 2)Study completedNCT02988466
What this trial is testing

Reduced Intensity (RIC) Conditioning And Transplantation of HLA-Haplo-HCT

Who this might be right for
Hematologic Malignancies
Masonic Cancer Center, University of Minnesota 78
Testing effectiveness (Phase 2)UnknownNCT03242603
What this trial is testing

Immunotherapy of Neuroblastoma Patients Using a Combination of Anti-GD2 and NK Cells

Who this might be right for
Neuroblastoma Recurrent
National University Hospital, Singapore 5
Testing effectiveness (Phase 2)Looking for participantsNCT06026657
What this trial is testing

Gemcitabine and Ex Vivo Expanded Allogenic Universal Donor, TGFβi Natural Killer (NK) Cells With or Without Naxitamab (Danyelza) for the Treatment of Patients With Metastatic, GD2 Expressing, HER2 Negative Breast Cancer

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8HER2-Negative Breast Carcinoma
Margaret Gatti-Mays 42
Early research (Phase 1)Study completedNCT00569283
What this trial is testing

Donor Natural Killer Cell Infusion in Preventing Relapse or Graft Failure in Patients Who Have Undergone Donor Bone Marrow Transplant

Who this might be right for
Cancer
Asan Medical Center 18
Testing effectiveness (Phase 2)Looking for participantsNCT07589530
What this trial is testing

Phase 1/2 Study of EB-NK-301 (Allogeneic TROP2-CAR NK Cells) in Advanced TROP2-Expressing Solid Tumors

Who this might be right for
Advanced Solid TumorsMetastatic Solid TumorsTROP2-Expressing Solid Tumors
Beijing Biotech 60
Early research (Phase 1)Active Not RecruitingNCT03774654
What this trial is testing

CD19.CAR Allogeneic NKT for Patients With Relapsed or Refractory B-Cell Malignancies (ANCHOR)

Who this might be right for
Refractory B-Cell Non-Hodgkin LymphomaRefractory B-Cell Small Lymphocytic LymphomaRelapsed Adult ALL+2 more
Baylor College of Medicine 13
Testing effectiveness (Phase 2)Looking for participantsNCT05334693
What this trial is testing

Expanded Haploidentical Natural Killer Cells as Consolidation Strategy for Children/Young Adults With AML

Who this might be right for
Acute Myeloid Leukemia
Belarusian Research Center for Pediatric Oncology, Hematology and Immunology 15
Early research (Phase 1)Temporarily pausedNCT01974479
What this trial is testing

Pilot Study of Redirected Haploidentical Natural Killer Cell Infusions for B-Lineage Acute Lymphoblastic Leukemia

Who this might be right for
B-cell Acute Lymphoblastic Leukemia
National University Health System, Singapore 20
Early research (Phase 1)Looking for participantsNCT07011004
What this trial is testing

Natural Killer Cells in Combination With Atezolizumab in People With Acute Myelogenous Leukemia

Who this might be right for
Acute Myeloid Leukemia RefractoryAcute Myeloid Leukemia, in Relapse
Memorial Sloan Kettering Cancer Center 18
Early research (Phase 1)Looking for participantsNCT06044506
What this trial is testing

Autologous Natural Killer Cell Therapy for Hepatocellular Carcinoma

Who this might be right for
Hepatocellular Carcinoma
Dr Cipto Mangunkusumo General Hospital 3
Testing effectiveness (Phase 2)UnknownNCT02693236
What this trial is testing

DC Vaccine Combined With CIK Cells in Patients With Esophagus Cancer

Who this might be right for
Esophagus Cancer
Affiliated Hospital to Academy of Military Medical Sciences 30
Testing effectiveness (Phase 2)Active Not RecruitingNCT04836728
What this trial is testing

Phase II Study of Chemotherapy and PD-1 Inhibitor Combination With Autologous CIK Cell Immunotherapy to Treat Lung Cancer

Who this might be right for
Non-small Cell Lung Cancer MetastaticFirst-line Treatment
Tianjin Medical University Cancer Institute and Hospital 156
Early research (Phase 1)Active Not RecruitingNCT04623944
What this trial is testing

NKX101, Intravenous Allogeneic CAR NK Cells, in Adults With AML or MDS

Who this might be right for
Relapsed/Refractory AMLAML, AdultMDS+1 more
Nkarta, Inc. 61
Testing effectiveness (Phase 2)Looking for participantsNCT07627711
What this trial is testing

Dual-Target CAR-NK Cells Targeting Mesothelin (MSLN) and MUC1 in Advanced Pancreatic Ductal Adenocarcinoma

Who this might be right for
Pancreatic Ductal Adenocarcinoma (PDAC)Unresectable Locally AdvancedMetastatic Disease
Beijing Biotech 42
Not applicableLooking for participantsNCT06678724
What this trial is testing

Establishment of a Microfluidic Based Liquid Biopsy Platform for Recurrent/Metastatic Head and Neck Cancers Prognostication Using NK Cell IFN-γ Expression and CTM Correlation With DS-SACA Chip

Who this might be right for
Head and Neck Cancers- Squamous CellHead and Neck Cancer MetastaticRecurrent Head and Neck Squamous Cell Carcinoma
National Taiwan University Hospital 30
Early research (Phase 1)Study completedNCT01385423
What this trial is testing

Haploidentical Donor Natural Killer Cell Infusion With IL-15 in Acute Myelogenous Leukemia (AML)

Who this might be right for
Acute Myelogenous LeukemiaMyelodysplastic Syndrome
Masonic Cancer Center, University of Minnesota 26
Early research (Phase 1)WithdrawnNCT04955262
What this trial is testing

A CD8 Positron Emission Tomography With Computed Tomography (PET/CT) Study Using ⁸⁹Zr Df-IAB22M2C in Patients With Metastatic Melanoma Receiving Bempegaldesleukin (NKTR-214) and Nivolumab

Who this might be right for
Metastatic Melanoma
Nektar Therapeutics
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