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Results for “Neoadjuvant Treatment for HER2-positive, ER-positive Breast Cancer”

33 trials

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Showing 20 of 33 results

Testing effectiveness (Phase 2)UnknownNCT04858516
What this trial is testing

Neoadjuvant Treatment With Palbociclib and Exemestane Plus Trastuzumab and Pyrotinib in Estrogen Receptor (ER)-Positive, HER2-positive Breast Cancer

Who this might be right for
Neoadjuvant Treatment for HER2-positive, ER-positive Breast Cancer
Guangdong Provincial People's Hospital 57
Testing effectiveness (Phase 2)Study completedNCT03644186
What this trial is testing

To Reduce the Use of Chemotherapy in Postmenopausal Patients With ER-positive and HER2-positive Breast Cancer (TOUCH)

Who this might be right for
Breast CancerEstrogen Receptor Positive TumorHER2-positive Breast Cancer
ETOP IBCSG Partners Foundation 147
Testing effectiveness (Phase 2)Looking for participantsNCT05837455
What this trial is testing

NeoTAILOR: ABiomarker-directed Approach to Guide Neoadjuvant Therapy for Patients With Stage II/III ER-positive, HER2-negative Breast Cancer

Who this might be right for
Breast CancerCancer of the Breast
Washington University School of Medicine 81
Testing effectiveness (Phase 2)WithdrawnNCT04038489
What this trial is testing

COX Inhibition and Biomarkers During Neoadjuvant Chemoendocrine Therapy for ER+, HER2- Stage I-III Breast Cancer

Who this might be right for
Breast CancerEstrogen Receptor-positive Breast Cancer
University of Virginia
Testing effectiveness (Phase 2)Looking for participantsNCT05296746
What this trial is testing

Neoadjuvant and Adjuvant Ribociclib and ET for Clinically High-risk ER+ and HER2- Breast Cancer

Who this might be right for
Breast Cancer Stage II
SOLTI Breast Cancer Research Group 1,100
Testing effectiveness (Phase 2)Ended earlyNCT00194792
What this trial is testing

Hormone Therapy and Combination Chemotherapy Before and After Surgery in Treating Patients With Stage I-IIIA Breast Cancer

Who this might be right for
Estrogen Receptor-positive Breast CancerHER2-negative Breast CancerProgesterone Receptor-positive Breast Cancer+3 more
University of Washington 28
Testing effectiveness (Phase 2)Looking for participantsNCT05607004
What this trial is testing

(Z)-Endoxifen for the Treatment of Premenopausal Women With ER+/HER2- Breast Cancer

Who this might be right for
Breast NeoplasmsInvasive Breast CancerEstrogen-receptor-positive Breast Cancer+1 more
Atossa Therapeutics, Inc. 87
Testing effectiveness (Phase 2)Study completedNCT02005887
What this trial is testing

TRial on the Endocrine Activity of Neoadjuvant Degarelix

Who this might be right for
Breast Cancer Invasive Nos
ETOP IBCSG Partners Foundation 51
Large-scale testing (Phase 3)Study completedNCT00553358
What this trial is testing

Neo ALTTO (Neoadjuvant Lapatinib and/or Trastuzumab Treatment Optimisation) Study

Who this might be right for
Neoplasms, Breast
Novartis Pharmaceuticals 455
Early research (Phase 1)Ended earlyNCT03128619
What this trial is testing

Copanlisib, Letrozole, and Palbociclib in Treating Patients With Hormone Receptor Positive HER2 Negative Stage I-IV Breast Cancer

Who this might be right for
Estrogen Receptor PositiveHER2/Neu NegativeInvasive Breast Carcinoma+14 more
Jonsson Comprehensive Cancer Center 10
Testing effectiveness (Phase 2)UnknownNCT01709370
What this trial is testing

Letrozole and CDK 4/6 Inhibitor for ER Positive, HER2 Negative Breast Cancer in Postmenopausal Women

Who this might be right for
ER Positive, HER2 Negative Breast Cancer
Organisation for Oncology and Translational Research 45
Large-scale testing (Phase 3)Active Not RecruitingNCT03725059
What this trial is testing

Study of Pembrolizumab (MK-3475) Versus Placebo in Combination With Neoadjuvant Chemotherapy & Adjuvant Endocrine Therapy in the Treatment of Early-Stage Estrogen Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative (ER+/HER2-) Breast Cancer (MK-3475-756/KEYNOTE-756)

Who this might be right for
Breast Cancer
Merck Sharp & Dohme LLC 1,240
Large-scale testing (Phase 3)Active Not RecruitingNCT01953588
What this trial is testing

Fulvestrant and/or Anastrozole in Treating Postmenopausal Patients With Stage II-III Breast Cancer Undergoing Surgery

Who this might be right for
Estrogen Receptor-positive Breast CancerHER2-negative Breast CancerInvasive Ductal Breast Carcinoma+6 more
Alliance for Clinical Trials in Oncology 1,473
Not applicableLooking for participantsNCT02945579
What this trial is testing

Multicenter Trial for Eliminating Breast Cancer Surgery or Radiotherapy in Exceptional Responders to Neoadjuvant Systemic Therapy

Who this might be right for
Estrogen Receptor NegativeHER2 Positive Breast CarcinomaHER2/Neu Negative+9 more
M.D. Anderson Cancer Center 120
Testing effectiveness (Phase 2)Study completedNCT00194779
What this trial is testing

Combination Chemotherapy and Filgrastim Before Surgery in Treating Patients With HER2-Positive Breast Cancer That Can Be Removed By Surgery

Who this might be right for
Estrogen Receptor-negative Breast CancerEstrogen Receptor-positive Breast CancerHER2-positive Breast Cancer+6 more
University of Washington 50
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07410559
What this trial is testing

Neoadjuvant Imlunestrant Plus Abemaciclib Treatment Guided by Ki67 Index After 2 Weeks for ER-Positive HER2-Negative Breast Cancer

Who this might be right for
Breast Cancer
Fudan University 189
Testing effectiveness (Phase 2)Ended earlyNCT02598310
What this trial is testing

Neoadjuvant Nab-PTX and Trastuzumab for ER Negative and HER2 Positive Breast Cancer

Who this might be right for
Breast CancerEstrogen Receptor Negative NeoplasmHER-2 Positive Breast Cancer
Osaka Medical College 30
Testing effectiveness (Phase 2)Ended earlyNCT01368263
What this trial is testing

Goserelin and Letrozole or Anastrozole in Premenopausal Patients With Stage II-III Estrogen Receptor-Positive Breast Cancer

Who this might be right for
Estrogen Receptor-positive Breast CancerHER2-negative Breast CancerStage II Breast Cancer+3 more
Washington University School of Medicine 8
Testing effectiveness (Phase 2)UnknownNCT02214004
What this trial is testing

Neoadjuvant Trastuzumab and Letrozole for Postmenopausal Women

Who this might be right for
Breast Cancer
Gangnam Severance Hospital 132
Testing effectiveness (Phase 2)Active Not RecruitingNCT01723774
What this trial is testing

PD 0332991 and Anastrozole for Stage 2 or 3 Estrogen Receptor Positive and HER2 Negative Breast Cancer

Who this might be right for
Breast Neoplasms
Washington University School of Medicine 84
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