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Results for “Neoplasm, Advanced or Metastatic”

4,960 trials

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Showing 20 of 4,960 results

Large-scale testing (Phase 3)Looking for participantsNCT06927986
What this trial is testing

Phase III Trial of SYS6010 Versus Platinum-based Chemotherapy for EGFR-mutated NSCLC（SYNSTAR01）

Who this might be right for
EGFR-mutated Locally Advanced or Metastatic NSCLC
CSPC Megalith Biopharmaceutical Co.,Ltd. 380
Early research (Phase 1)Looking for participantsNCT05176483
What this trial is testing

Study of Zanzalintinib in Combination With Immuno-Oncology Agents in Participants With Solid Tumors

Who this might be right for
Renal Cell Carcinoma (RCC)Metastatic Castration-Resistant Prostate Cancer (mCRPC)Urothelial Carcinoma (UC)+7 more
Exelixis 1,314
Early research (Phase 1)UnknownNCT03282617
What this trial is testing

Dendritic Cell Therapy With CD137L-DC-EBV-VAX in Locally Advanced Stage IV or Locally Recurrent/Metastatic Nasopharyngeal Carcinoma

Who this might be right for
Nasopharyngeal Cancer
National University Hospital, Singapore 55
Early research (Phase 1)WithdrawnNCT02105350
What this trial is testing

MEK162 With Gemcitabine and Oxaliplatin in Biliary Cancer

Who this might be right for
Biliary Tract CarcinomaGallbladder Carcinoma
University Health Network, Toronto
Large-scale testing (Phase 3)Looking for participantsNCT06767527
What this trial is testing

AK112 or Placebo Plus Nab-Paclitaxel as First-line Treatment in Inoperable Locally Advanced/ Metastatic Triple-negative Breast Cancer

Who this might be right for
Triple-Negative Breast Cancer (TNBC)
Akeso 416
Testing effectiveness (Phase 2)Study completedNCT03665285
What this trial is testing

A Safety and Tolerability Study of NC318 in Subjects With Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced or Metastatic Solid TumorsLung CancerBreast Cancer+6 more
NextCure, Inc. 109
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07360743
What this trial is testing

Immunotherapy Without Chemotherapy for Advanced Lung Cancer Patients With High PD-L1 Levels

Who this might be right for
Non Small Cell Lung Cancer (Squamous or Non Squamous)
UNICANCER 275
Testing effectiveness (Phase 2)Study completedNCT05661578
What this trial is testing

Evaluate the Safety and Pharmacokinetics of the Intravenous Fixed-Dose Combination (IV FDC) of Tiragolumab and Atezolizumab in Participants With Locally Advanced, Recurrent or Metastatic Solid Tumors

Who this might be right for
PD-L1-selected Solid Tumors
Hoffmann-La Roche 64
Early research (Phase 1)Active Not RecruitingNCT05339685
What this trial is testing

BL-M02D1 in Patients With Locally Advanced or Metastatic Triple Negative Breast Cancer or Other Solid Tumors

Who this might be right for
Breast Cancer
Sichuan Baili Pharmaceutical Co., Ltd. 82
Early research (Phase 1)Active Not RecruitingNCT04188548
What this trial is testing

LY3484356 in Participants With Advanced or Metastatic Breast Cancer or Endometrial Cancer

Who this might be right for
Breast CancerAdvanced Breast CancerMetastatic Breast Cancer+1 more
Eli Lilly and Company 500
Testing effectiveness (Phase 2)Study completedNCT01016015
What this trial is testing

Temsirolimus and Cixutumumab in Treating Patients With Locally Advanced, Metastatic, or Recurrent Soft Tissue Sarcoma or Bone Sarcoma

Who this might be right for
Metastatic OsteosarcomaRecurrent Adult Soft Tissue SarcomaRecurrent Osteosarcoma+2 more
National Cancer Institute (NCI) 178
Testing effectiveness (Phase 2)UnknownNCT04318223
What this trial is testing

Palbociclib Plus Fulvestrant in Women With Hormone Receptor Positive and Human Epidermal Growth Factor Receptor Type 2 Negative Locally Advanced or Metastatic Breast Cancer Previously Treated With a CDK4/6 Inhibitor in Combination With Hormonal Therapy

Who this might be right for
Metastatic Breast CancerLocally Advanced Breast Cancer
Consorzio Oncotech 168
Early research (Phase 1)Ended earlyNCT06420349
What this trial is testing

NXP800 for the Treatment of Patients With Advanced or Metastatic Cholangiocarcinoma

Who this might be right for
Advanced CholangiocarcinomaMetastatic CholangiocarcinomaRefractory Cholangiocarcinoma+4 more
Mayo Clinic 7
Testing effectiveness (Phase 2)Study completedNCT03685448
What this trial is testing

ANZUP - Non-clear Cell Post Immunotherapy CABozantinib (UNICAB)

Who this might be right for
Renal Cell CarcinomaPapillary Renal Cell Carcinoma Type 1Papillary Renal Cell Carcinoma Type 2+3 more
Australian and New Zealand Urogenital and Prostate Cancer Trials Group 35
Early research (Phase 1)Study completedNCT02070549
What this trial is testing

Trametinib in Treating Patients With Advanced Cancer With or Without Hepatic Dysfunction

Who this might be right for
Advanced Malignant Solid NeoplasmMetastatic Malignant Neoplasm in the LiverMetastatic Malignant Solid Neoplasm+1 more
National Cancer Institute (NCI) 46
Testing effectiveness (Phase 2)Study completedNCT00755885
What this trial is testing

Abiraterone Acetate in Treating Postmenopausal Women With Advanced or Metastatic Breast Cancer

Who this might be right for
Breast Cancer
Cancer Research UK 77
Testing effectiveness (Phase 2)Ended earlyNCT00595985
What this trial is testing

Sorafenib as a Second Line Treatment in Patients With Advanced or Metastatic Gastric Cancer

Who this might be right for
Gastric Cancer
Fudan University 5
Early research (Phase 1)Study completedNCT05858710
What this trial is testing

Study of DPPG2-TSL-DOX Combined With Hyperthermia in Soft Tissue Sarcoma

Who this might be right for
Sarcoma, Soft Tissue
Thermosome GmbH 8
Not applicableStudy completedNCT02285361
What this trial is testing

GIOTRIF rPMS in Korean Patients With NSCLC

Who this might be right for
Carcinoma, Non-Small-Cell Lung
Boehringer Ingelheim 1,272
Testing effectiveness (Phase 2)Active Not RecruitingNCT05585320
What this trial is testing

A Phase 1/2a Study of IMM-1-104 in Participants With Advanced or Metastatic Solid Tumors

Who this might be right for
Advanced Solid TumorPancreatic AdenocarcinomaMalignant Melanoma (Cutaneous)+1 more
Immuneering Corporation 209
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