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Results for “Neratinib”

80 trials

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Showing 20 of 80 results

Not applicableLooking for participantsNCT06892093
What this trial is testing

Probiotics for Prevention of Neratinib-Induced Diarrhea in Breast Cancer Patients

Who this might be right for
HER2-positive Breast CancerDiarrhea Caused by DrugNeratinib
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University 308
Testing effectiveness (Phase 2)Ended earlyNCT04460430
What this trial is testing

Targeting EGFR/ERBB2 With Neratinib in Hormone Receptor (HR)-Positive/HER2-negative HER2-enriched Advanced/Metastatic Breast Cancer

Who this might be right for
Breast Cancer
SOLTI Breast Cancer Research Group 12
Testing effectiveness (Phase 2)Study completedNCT00706030
What this trial is testing

Study Evaluating Neratinib (HKI-272) In Combination With Vinorelbine In Subjects With Solid Tumors And Metastatic Breast Cancer

Who this might be right for
Breast CancerAdvanced Malignant Solid Tumors
Puma Biotechnology, Inc. 92
Testing effectiveness (Phase 2)Active Not RecruitingNCT03377387
What this trial is testing

Capecitabine 7/7 Schedule With Neratinib in Patients With Metastatic HER2-Positive Breast Cancer

Who this might be right for
Breast Cancer
Memorial Sloan Kettering Cancer Center 34
Testing effectiveness (Phase 2)Ended earlyNCT01953926
What this trial is testing

Basket Study of Neratinib in Participants With Solid Tumors Harboring Somatic HER2 or EGFR Exon 18 Mutations

Who this might be right for
Solid Tumors Harboring Somatic HER2 or EGFR Exon 18 Mutations
Puma Biotechnology, Inc. 582
Large-scale testing (Phase 3)Study completedNCT00878709
What this trial is testing

Study Evaluating The Effects Of Neratinib After Adjuvant Trastuzumab In Women With Early Stage Breast Cancer

Who this might be right for
Breast Cancer
Puma Biotechnology, Inc. 2,840
Testing effectiveness (Phase 2)Active Not RecruitingNCT06109467
What this trial is testing

Neratinib In Combination With Chemotherapy/Trastuzumab/Pembrolizumab In HER2 Gastroesophageal Cancer

Who this might be right for
GastroEsophageal CancerGastric Cancer
H. Lee Moffitt Cancer Center and Research Institute 8
Testing effectiveness (Phase 2)WithdrawnNCT01960023
What this trial is testing

Safety and Efficacy Study of Neratinib and Cetuximab to Treat Patients With Quadruple Wild-Type Metastatic Colorectal Cancer

Who this might be right for
Colorectal Cancer
NSABP Foundation Inc
Testing effectiveness (Phase 2)WithdrawnNCT05512182
What this trial is testing

Efficacy of Triplet Combination With Pembrolizumab, Neratinib, and Paclitaxel as a Second Line Treatment in Recurrent/Advanced Gastric Cancer Having Somatic Human Epidermal Growth Factor Receptor Family (EGFR, HER2, HER3, HER4) Mutations or HER2 Amplification/Overexpression

Who this might be right for
Recurrent/Advanced Gastric Cancer
Yonsei University
Testing effectiveness (Phase 2)Study completedNCT01111825
What this trial is testing

Temsirolimus Plus Neratinib for Patients With Metastatic HER2-Amplified or Triple Negative Breast Cancer

Who this might be right for
Breast Cancer
Puma Biotechnology, Inc. 99
Testing effectiveness (Phase 2)Study completedNCT00398567
What this trial is testing

HKI-272 (Neratinib) in Combination With Trastuzumab (Herceptin) In Subjects With Advanced Breast Cancer

Who this might be right for
Advanced Breast Cancer
Puma Biotechnology, Inc. 45
Testing effectiveness (Phase 2)Active Not RecruitingNCT05252988
What this trial is testing

Three Antidiarrheal Strategies in HER2+/HR+ Early Breast Cancer Patients Treated With Extended Adjuvant Neratinib

Who this might be right for
Early-stage Breast CancerHER2 Positive Breast CancerHormone Receptor Positive
Spanish Breast Cancer Research Group 177
Early research (Phase 1)Active Not RecruitingNCT04502602
What this trial is testing

Niraparib and Neratinib in Advanced Solid Tumors With Expansion Cohort in Advanced Ovarian Cancer

Who this might be right for
Advanced Solid TumorOvarian Cancer
Virginia Commonwealth University 18
Testing effectiveness (Phase 2)Study completedNCT00777101
What this trial is testing

Study Evaluating Neratinib Versus Lapatinib Plus Capecitabine For ErbB2 Positive Advanced Breast Cancer

Who this might be right for
Advanced Breast CancerBreast Cancer
Puma Biotechnology, Inc. 233
Early research (Phase 1)Study completedNCT00757809
What this trial is testing

Study Evaluating The Tolerability Of Multiple Doses Of HKI-272

Who this might be right for
Healthy Subjects
Puma Biotechnology, Inc. 50
Early research (Phase 1)WithdrawnNCT00932464
What this trial is testing

Study Evaluating The Effect Of A High-Fat Meal On The Pharmacokinetics Of Neratinib

Who this might be right for
Healthy
Puma Biotechnology, Inc.
Not applicableLooking for participantsNCT06693024
What this trial is testing

Adjuvant Therapy With Neratinib in HER2 Positive Early Breast Cancer

Who this might be right for
HER2-positive Breast Cancer
Shu Wang 2,806
Testing effectiveness (Phase 2)Looking for participantsNCT05919108
What this trial is testing

Neoadjuvant Neratinib in Stage I-III HER2-Mutated Lobular Breast Cancers

Who this might be right for
Anatomic Stage I Breast CancerAnatomic Stage II Breast CancerAnatomic Stage III Breast Cancer+1 more
Vanderbilt-Ingram Cancer Center 30
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07152782
What this trial is testing

T-DXd With or Without Neratinib for HER2 Positive Breast Cancer With Brain Metastasis

Who this might be right for
Breast Cancer With Brain MetastasisHER2-positive Breast Cancer
Fudan University 202
Early research (Phase 1)Ended earlyNCT02593708
What this trial is testing

Phase1 of Neratinib+Trastuzumab, Pertuzumab, Paclitaxel in Patients With Advanced Solid Tumors/HER2+

Who this might be right for
Solid Tumor
Michelle Melisko 6
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