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Results for “Neratinib”

79 trials

Showing 20 of 79 results

Early research (Phase 1)Study completedNCT01423123
What this trial is testing

Combination of Weekly Paclitaxel With Neratinib and Trastuzumab in Women With Metastatic HER2-positive Breast Cancer

Who this might be right for
Breast Cancer
NSABP Foundation Inc 21
Testing effectiveness (Phase 2)Study completedNCT04366713
What this trial is testing

Characterize Colon Pathology in Patients With HER2 Amplified Breast Cancer Treated With Neratinib

Who this might be right for
HER2 Amplified Breast Cancer
Puma Biotechnology, Inc. 6
Very early researchLooking for participantsNCT06008275
What this trial is testing

Neratinib in Combination With Ruxolitinib in Patients With mTNBC

Who this might be right for
Metastatic Triple-Negative Breast CarcinomaBreast Cancer
Baylor Research Institute 20
Testing effectiveness (Phase 2)Study completedNCT00266877
What this trial is testing

Study Evaluating the Safety Of HKI-272 (Neratinib) In Subjects With Advanced Non-Small Cell Lung Cancer

Who this might be right for
Carcinoma, Non-Small-Cell LungLung Neoplasms
Puma Biotechnology, Inc. 172
Testing effectiveness (Phase 2)Study completedNCT00300781
What this trial is testing

Study Evaluating HKI-272 (Neratinib) In Subjects With Advanced Breast Cancer

Who this might be right for
Breast NeoplasmsNeoplasms
Puma Biotechnology, Inc. 136
Early research (Phase 1)Study completedNCT00860223
What this trial is testing

Study Evaluating The Potential Effect Of Multiple Doses Of Neratinib On The Pharmacokinetics Of A Single Dose Of Digoxin

Who this might be right for
Healthy
Puma Biotechnology, Inc. 27
Testing effectiveness (Phase 2)Ended earlyNCT01953926
What this trial is testing

Basket Study of Neratinib in Participants With Solid Tumors Harboring Somatic HER2 or EGFR Exon 18 Mutations

Who this might be right for
Solid Tumors Harboring Somatic HER2 or EGFR Exon 18 Mutations
Puma Biotechnology, Inc. 582
Testing effectiveness (Phase 2)Study completedNCT00398567
What this trial is testing

HKI-272 (Neratinib) in Combination With Trastuzumab (Herceptin) In Subjects With Advanced Breast Cancer

Who this might be right for
Advanced Breast Cancer
Puma Biotechnology, Inc. 45
Early research (Phase 1)Study completedNCT00781430
What this trial is testing

Study Evaluating The PK And Safety Of Neratinib In Healthy Subjects And Subjects With Chronic Liver Disease

Who this might be right for
Hepatic Insufficiency
Puma Biotechnology, Inc. 27
Early research (Phase 1)Active Not RecruitingNCT04502602
What this trial is testing

Niraparib and Neratinib in Advanced Solid Tumors With Expansion Cohort in Advanced Ovarian Cancer

Who this might be right for
Advanced Solid TumorOvarian Cancer
Virginia Commonwealth University 18
Early research (Phase 1)Study completedNCT00864487
What this trial is testing

Study Evaluating The Potential Effect Of Rifampin On The Pharmacokinetics Of Neratinib

Who this might be right for
Healthy Subjects
Puma Biotechnology, Inc. 24
Early research (Phase 1)Study completedNCT01128842
What this trial is testing

Neratinib (HKI-272) And Capecitabine In Japanese With Solid Tumor

Who this might be right for
Advanced Malignant Solid Tumors
Puma Biotechnology, Inc. 7
Testing effectiveness (Phase 2)Study completedNCT01494662
What this trial is testing

HKI-272 for HER2-Positive Breast Cancer and Brain Metastases

Who this might be right for
Breast Cancer
Dana-Farber Cancer Institute 140
Testing effectiveness (Phase 2)WithdrawnNCT04781374
What this trial is testing

Neratinib in Patients With Metastatic Castration-Resistant Prostate Cancer

Who this might be right for
Metastatic Prostate AdenocarcinomaCastration-resistant Prostate CancerProstate Cancer+1 more
Beth Israel Deaconess Medical Center
Testing effectiveness (Phase 2)Study completedNCT01111825
What this trial is testing

Temsirolimus Plus Neratinib for Patients With Metastatic HER2-Amplified or Triple Negative Breast Cancer

Who this might be right for
Breast Cancer
Puma Biotechnology, Inc. 99
Not applicableNo Longer AvailableNCT01956253
What this trial is testing

Single Subject Neratinib in Bladder Cancer (NRR)

Who this might be right for
Bladder Cancer
UNC Lineberger Comprehensive Cancer Center
Early research (Phase 1)Temporarily pausedNCT05372614
What this trial is testing

Testing the Safety and Tolerability of the Anti-cancer Drugs Trastuzumab Deruxtecan and Neratinib for Cancers With Changes in the HER2 Gene

Who this might be right for
Metastatic Malignant Solid NeoplasmUnresectable Malignant Solid Neoplasm
National Cancer Institute (NCI) 33
Testing effectiveness (Phase 2)Study completedNCT00915018
What this trial is testing

Study Evaluating Neratinib Plus Paclitaxel VS Trastuzumab Plus Paclitaxel In ErbB-2 Positive Advanced Breast Cancer

Who this might be right for
Breast Cancer
Puma Biotechnology, Inc. 479
Testing effectiveness (Phase 2)Study completedNCT00706030
What this trial is testing

Study Evaluating Neratinib (HKI-272) In Combination With Vinorelbine In Subjects With Solid Tumors And Metastatic Breast Cancer

Who this might be right for
Breast CancerAdvanced Malignant Solid Tumors
Puma Biotechnology, Inc. 92
Testing effectiveness (Phase 2)UnknownNCT05154396
What this trial is testing

Neratinib Dose Escalation Regimen for HER2 Positive Early Breast Cancer

Who this might be right for
HER2-positive Breast Cancer
Chinese Academy of Medical Sciences 60
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