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Results for “Nervous System Heredodegenerative Disorder”

2,467 trials

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Showing 20 of 2,467 results

Not applicableStudy completedNCT00026000
What this trial is testing

Brain Activation in Vocal and Motor Tics

Who this might be right for
Tourette's SyndromeChronic Motor Tic DisorderChronic Motor Vocal Disorder
National Institute of Neurological Disorders and Stroke (NINDS) 30
Not applicableStudy completedNCT04198207
What this trial is testing

The Effectiveness and Safety of Vagus Nerve Stimulation for TRE

Who this might be right for
Tuberous Sclerosis ComplexEpilepsy
Beijing Children's Hospital 70
Early research (Phase 1)Ended earlyNCT00996892
What this trial is testing

Safety, Tolerability and Pharmacokinetics of Cobimetinib in Combination With Pictilisib in Patients With Locally Advanced or Metastatic Solid Tumors

Who this might be right for
Solid Tumors
Genentech, Inc. 178
Early research (Phase 1)Study completedNCT02211768
What this trial is testing

Transformation of Plexiform Neurofibromas to Malignant Peripheral Nerve Sheath Tumors in Neurofibromatosis Type 1

Who this might be right for
NeurofibromatosisMPNST
National Cancer Institute (NCI) 10
Early research (Phase 1)UnknownNCT02728115
What this trial is testing

Safety Evaluation of Cellavita HD Administered Intravenously in Participants With Huntington's Disease

Who this might be right for
Huntington Disease
Azidus Brasil 6
Testing effectiveness (Phase 2)Study completedNCT03862950
What this trial is testing

A Trial of Metformin in Individuals With Fragile X Syndrome (Met)

Who this might be right for
Fragile X SyndromeFragile X Mental Retardation SyndromeMental Retardation, X-Linked+7 more
University of Alberta 125
Testing effectiveness (Phase 2)Study completedNCT00529308
What this trial is testing

Transcranial Magnetic Stimulation (TMS) for Individuals With Tourette's Syndrome

Who this might be right for
Tourette Syndrome
Yale University 20
Not applicableStudy completedNCT04920110
What this trial is testing

Development of the ORCA Communication Measure for Rett Syndrome

Who this might be right for
Rett Syndrome
Rett Syndrome Research Trust 272
Testing effectiveness (Phase 2)Active Not RecruitingNCT05467397
What this trial is testing

Feasibility of [11C]Acetate-PET in LAM and TSC

Who this might be right for
LymphangioleiomyomatosisTuberous Sclerosis Complex
Brigham and Women's Hospital 7
Testing effectiveness (Phase 2)Ended earlyNCT01968590
What this trial is testing

Vitamin D Supplementation for Adults With Neurofibromatosis Type 1 (NF1)

Who this might be right for
Neurofibromatosis Type 1 (NF1)
University of Utah 26
Early research (Phase 1)Study completedNCT00824590
What this trial is testing

A Phase 1, Non-Randomized, Open-Label, Single-Dose Study To Evaluate The Pharmacokinetics, Safety, And Tolerability Of Dimebon [PF 01913539] In Subjects With Severely-Impaired And Normal Renal Function

Who this might be right for
Alzheimer's DiseaseHuntington's Disease
Pfizer 20
Not applicableLooking for participantsNCT05007990
What this trial is testing

Caregiving Networks Across Disease Context and the Life Course

Who this might be right for
Inherited Metabolic DisordersUndiagnosed DiseasesBatten's Disease+2 more
National Human Genome Research Institute (NHGRI) 2,800
Not applicableEnded earlyNCT06014541
What this trial is testing

Observational Study to Characterize Biomarkers and Disease Progression in Participants With Methyl CpG Binding Protein 2 (MECP2) Duplication Syndrome

Who this might be right for
Methyl CpG Binding Protein 2 (MECP2) Duplication Syndrome
Ionis Pharmaceuticals, Inc. 29
Not applicableStudy completedNCT02325505
What this trial is testing

Characterization of Patients With Tuberous Sclerosis Complex, Lymphangioleiomyomatosis and Angiomyolipoma

Who this might be right for
Tuberous SclerosisLymphangioleiomyomatosisAngiomyolipoma
InCor Heart Institute 200
Testing effectiveness (Phase 2)Study completedNCT05005845
What this trial is testing

NFX-179 Topical Gel Treatment for Adults With Neurofibromatosis 1 (NF1) and Cutaneous Neurofibromas (cNF)

Who this might be right for
Cutaneous NeurofibromaNeurofibromatosis 1
NFlection Therapeutics, Inc. 199
Not applicableStudy completedNCT02465931
What this trial is testing

Decisional Capacity and Informed Consent in Fragile X Syndrome

Who this might be right for
Fragile X Syndrome (FXS)
RTI International 152
Not applicableLooking for participantsNCT01574053
What this trial is testing

Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort

Who this might be right for
Huntington's Disease
CHDI Foundation, Inc. 35,000
Large-scale testing (Phase 3)Ended earlyNCT01085266
What this trial is testing

An Extension of the HORIZON Protocol Evaluating the Safety of Dimebon (Latrepirdine) in Subjects With Huntington Disease

Who this might be right for
Huntington Disease
Medivation, Inc. 362
Large-scale testing (Phase 3)Active Not RecruitingNCT05606614
What this trial is testing

A Phase 1/2/3 Study of TSHA-102 Gene Therapy in Females With Rett Syndrome (REVEAL Pivotal Study)

Who this might be right for
Rett Syndrome
Taysha Gene Therapies, Inc. 17
Not applicableLooking for participantsNCT03789721
What this trial is testing

Adrenoleukodystrophy National Registry Study

Who this might be right for
ALD (Adrenoleukodystrophy)AdrenoleukodystrophyCerebral Adrenoleukodystrophy
Masonic Cancer Center, University of Minnesota 1,000
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