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Results for “Neurofibroma, Plexiform”

79 trials

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Showing 20 of 79 results

Very early researchStudy completedNCT01275586
What this trial is testing

Study of Tasigna®/Nilotinib (AMN107) in Neurofibromatosis (NF1) Patients With Plexiform Neurofibromas

Who this might be right for
NeurofibromatosisNF1Neurofibromas
Indiana University 6
Testing effectiveness (Phase 2)Active Not RecruitingNCT02407405
What this trial is testing

MEK 1/2 Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) in Adults With Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas

Who this might be right for
Neurofibromatosis 1 (NF1)Plexiform Neurofibromas (PN)
National Cancer Institute (NCI) 36
Testing effectiveness (Phase 2)Study completedNCT00030264
What this trial is testing

Combination Chemotherapy in Treating Patients With Neurofibromatosis and Progressive Plexiform Neurofibromas

Who this might be right for
Neurofibromatosis Type 1Precancerous Condition
Children's Hospital of Philadelphia 23
Testing effectiveness (Phase 2)Looking for participantsNCT06541847
What this trial is testing

A Phase 2, Open-Label Study to Evaluate the Safety and Effects of HLX-1502 in Patients With Neurofibromatosis Type 1

Who this might be right for
Neurofibromatosis Type 1
Healx Limited 25
Early research (Phase 1)Study completedNCT03649165
What this trial is testing

Evaluate Bioavailability and Food Effect of Selumetinib (AZD6244) in Healthy Male Participants

Who this might be right for
Neurofibromatosis Type 1 (NF1)-Related Plexiform Neurofibromas (PNs)Healthy Participants
AstraZeneca 24
Large-scale testing (Phase 3)Active Not RecruitingNCT02180867
What this trial is testing

Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery

Who this might be right for
Alveolar Soft Part SarcomaAngiomatoid Fibrous HistiocytomaAtypical Fibroxanthoma+33 more
National Cancer Institute (NCI) 140
Testing effectiveness (Phase 2)Study completedNCT03326388
What this trial is testing

Intermittent Dosing Of Selumetinib In Childhood NF1 Associated Tumours

Who this might be right for
Neurofibromatosis Type 1Plexiform NeurofibromaOptic Nerve Glioma
Great Ormond Street Hospital for Children NHS Foundation Trust 14
Testing effectiveness (Phase 2)Study completedNCT01673009
What this trial is testing

Phase II Study of Gleevec/Imatinib Mesylate (STI-571, NCS 716051) in Neurofibromatosis (NF1) Patients With Plexiform Neurofibromas

Who this might be right for
Neurofibromatosis
Indiana University 36
Not applicableUnknownNCT06379230
What this trial is testing

A Retrospective Study on Epidemiological Characteristics of Chinese NF1 Patients in Real World (PROMISE)

Who this might be right for
Neurofibromatosis 1Plexiform Neurofibroma
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University 2,000
Early research (Phase 1)Ended earlyNCT00716469
What this trial is testing

Phase I Clinical Study of the Safety of Photodynamic Therapy (PDT) Using LS11 in Children With Plexiform Neurofibromas

Who this might be right for
Neurofibroma
Children's Hospital of Philadelphia 7
Not applicableActive Not RecruitingNCT00924196
What this trial is testing

Natural History Study of Patients With Neurofibromatosis Type I

Who this might be right for
Neurofibromatosis Type 1Malignant Peripheral Nerve Sheath TumorPlexiform Neurofibroma+2 more
National Cancer Institute (NCI) 259
Testing effectiveness (Phase 2)UnknownNCT03741101
What this trial is testing

Treatment of NF1-related Plexiform Neurofibroma With Trametinib

Who this might be right for
Neurofibromatosis 1ChildNeurofibroma, Plexiform
Region Skane 15
Testing effectiveness (Phase 2)Active Not RecruitingNCT04954001
What this trial is testing

Study to Evaluate the Safety, Tolerability, PK Characteristics and Anti-tumor Activity of FCN-159 in Adult and Pediatric Participants With Neurofibromatosis Type 1

Who this might be right for
Neurofibromatosis 1Plexiform NeurofibromaNF1
Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd. 160
Testing effectiveness (Phase 2)Looking for participantsNCT06188741
What this trial is testing

Selumetinib for the Prevention of Plexiform Neurofibroma Growth in NF Type 1

Who this might be right for
Neurofibromatosis 1Plexiform Neurofibroma
University of Alabama at Birmingham 200
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06763315
What this trial is testing

Low-dose Selumetinib for the Treatment of Plexiform Neurofibromas in Chinese Children

Who this might be right for
Plexiform Neurofibromas (PN)
West China Hospital 50
Testing effectiveness (Phase 2)Active Not RecruitingNCT03962543
What this trial is testing

MEK Inhibitor Mirdametinib (PD-0325901) in Patients With Neurofibromatosis Type 1 Associated Plexiform Neurofibromas

Who this might be right for
Plexiform NeurofibromaNeurofibromatosis Type 1 (NF1)
SpringWorks Therapeutics, Inc., a healthcare company of Merck KGaA, Darmstadt, Germany 114
Testing effectiveness (Phase 2)Study completedNCT00754780
What this trial is testing

Clinical Trial of Pirfenidone in Adult Patients With Neurofibromatosis 1

Who this might be right for
Neurofibromatosis
Mayo Clinic 24
Not applicableLooking for participantsNCT05199376
What this trial is testing

Evaluation of Percutaneous Cryotherapy in the Treatment of Plexiform Neurofibromas and Unresectable Neurofibromas in Neurofibromatosis Type 1

Who this might be right for
NeurofibromaNeurofibroma, Plexiform
Centre Leon Berard 30
Not applicableLooking for participantsNCT06360406
What this trial is testing

Real-World Treatment Study of Koselugo (Selumetinib)

Who this might be right for
Neurofibromatosis 1Neurofibroma, Plexiform
AstraZeneca 200
Testing effectiveness (Phase 2)Ended earlyNCT02177825
What this trial is testing

Study of Imatinib Mesylate in Neurofibromatosis Type I Patients Aged 2 to 21 With Plexiform Neurofibromas

Who this might be right for
Plexiform Neurofibromas
St. Justine's Hospital 5
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