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Results for “Neurofibroma Plexiform”

79 trials

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Showing 20 of 79 results

Testing effectiveness (Phase 2)Study completedNCT01412892
What this trial is testing

Use of RAD001 as Monotherapy in the Treatment of Neurofibromatosis 1 Related Internal Plexiform Neurofibromas

Who this might be right for
Neurofibromatosis Type 1Plexiform NeurofibromaNeurofibromatoses
Assistance Publique - Hôpitaux de Paris 30
Not applicableLooking for participantsNCT06360406
What this trial is testing

Real-World Treatment Study of Koselugo (Selumetinib)

Who this might be right for
Neurofibromatosis 1Neurofibroma, Plexiform
AstraZeneca 200
Not applicableLooking for participantsNCT02544022
What this trial is testing

Development and Validation of Patient Reported Outcome (PRO) Measures for Individuals With Neurofibromatosis 1 (NF1) and Plexiform Neurofibromas (pNFs)

Who this might be right for
Neurofibromatosis 1Plexiform Neurofibromas
National Cancer Institute (NCI) 476
Testing effectiveness (Phase 2)Study completedNCT01140360
What this trial is testing

Pilot Study of Gleevec/Imatinib Mesylate (STI-571, NSC 716051) in Neurofibromatosis (NF1) Patient With Plexiform Neurofibromas

Who this might be right for
NeurofibromatosisNeurofibromas
Kent Robertson 21
Early research (Phase 1)Looking for participantsNCT06961565
What this trial is testing

PAS-004 in Adults Who Have Neurofibromatosis Type 1 With Plexiform Neurofibromas

Who this might be right for
NF1 MutationNeurofibroma PlexiformNeurofibroma, Plexiform+2 more
Pasithea Therapeutics Corp. 56
Not applicableWithdrawnNCT03027401
What this trial is testing

Clinical Sequencing of Cancer and Tissue Repository: OncoGenomics

Who this might be right for
NeoplasmsAdenomatous Polyposis ColiNeurofibroma, Plexiform+1 more
National Cancer Institute (NCI)
Not applicableStudy completedNCT00006435
What this trial is testing

Study of Plexiform Neurofibromas in Neurofibromatosis Type 1

Who this might be right for
Plexiform NeurofibromasNF1
National Cancer Institute (NCI) 24
Testing effectiveness (Phase 2)Study completedNCT00754780
What this trial is testing

Clinical Trial of Pirfenidone in Adult Patients With Neurofibromatosis 1

Who this might be right for
Neurofibromatosis
Mayo Clinic 24
Not applicableStudy completedNCT02777775
What this trial is testing

Targeting the Mechanisms Underlying Cutaneous Neurofibroma Formation in NF1: A Clinical Translational Approach.

Who this might be right for
Cutaneous NeurofibromasNeurofibromatosis Type 1Plexiform Neurofibromas
Corewell Health West 71
Testing effectiveness (Phase 2)Study completedNCT00021541
What this trial is testing

R115777 to Treat Children With Neurofibromatosis Type 1 and Progressive Plexiform Neurofibromas

Who this might be right for
Neurofibroma, PlexiformNeurofibromatosis Type I
National Cancer Institute (NCI) 62
Testing effectiveness (Phase 2)Looking for participantsNCT06239272
What this trial is testing

NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS)

Who this might be right for
Adipocytic NeoplasmLiposarcomaAtypical Fibroxanthoma+6 more
St. Jude Children's Research Hospital 139
Large-scale testing (Phase 3)Active Not RecruitingNCT05913037
What this trial is testing

FCN-159 in Adult Patients With Symptomatic, Inoperable Neurofibromatosis Type 1-Related Plexiform Neurofibromas

Who this might be right for
Neurofibromatosis 1Plexiform NeurofibromaNF1
Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd. 167
Testing effectiveness (Phase 2)Active Not RecruitingNCT03363217
What this trial is testing

Trametinib for Pediatric Neuro-oncology Patients With Refractory Tumor and Activation of the MAPK/ERK Pathway.

Who this might be right for
Low-grade GliomaPlexiform NeurofibromaCentral Nervous System Glioma
St. Justine's Hospital 114
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06763315
What this trial is testing

Low-dose Selumetinib for the Treatment of Plexiform Neurofibromas in Chinese Children

Who this might be right for
Plexiform Neurofibromas (PN)
West China Hospital 50
Not applicableNot Yet RecruitingNCT06507748
What this trial is testing

Evaluate the Feasibility of a Physiologic Biomarker to Assess Pain and Other Sensory Problems Using Pupillometry in Participants With Neurofibromatosis Type 1 (NF1)

Who this might be right for
Neurofibromatosis Type 1
National Cancer Institute (NCI) 70
Testing effectiveness (Phase 2)Ended earlyNCT02177825
What this trial is testing

Study of Imatinib Mesylate in Neurofibromatosis Type I Patients Aged 2 to 21 With Plexiform Neurofibromas

Who this might be right for
Plexiform Neurofibromas
St. Justine's Hospital 5
Testing effectiveness (Phase 2)Study completedNCT03231306
What this trial is testing

Phase II Study of Binimetinib in Children and Adults With NF1 Plexiform Neurofibromas

Who this might be right for
Neurofibromatosis Type 1Plexiform Neurofibroma
University of Alabama at Birmingham 45
Not applicableEnded earlyNCT05683678
What this trial is testing

US Selumetinib Registry

Who this might be right for
Neurofibromatosis Type 1Plexiform Neurofibromas
Alexion Pharmaceuticals, Inc. 37
Testing effectiveness (Phase 2)Ended earlyNCT01402817
What this trial is testing

Study of Sutent®/Sunitinib (SU11248) in Subjects With NF-1 Plexiform Neurofibromas

Who this might be right for
NeurofibromatosisNF1Plexiform Neurofibromas
Indiana University 19
Testing effectiveness (Phase 2)Study completedNCT00076102
What this trial is testing

Pirfenidone in Children and Young Adults With Neurofibromatosis Type I and Progressive Plexiform Neurofibromas

Who this might be right for
Neurofibromatosis 1Neurofibroma, Plexiform
National Cancer Institute (NCI) 36
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