Not applicableActive Not RecruitingNCT05388370What this trial is testingPASS of Paediatric Patients Initiating SelumetinibWho this might be right forNeurofibromatosis Type 1 AstraZeneca 124
Very early researchStudy completedNCT00657202What this trial is testingRanibizumab for Neurofibromas Associated With Neurofibromatosis 1Who this might be right forNeurofibromatosis Type 1Cutaneous Neurofibromas Massachusetts General Hospital 11
Testing effectiveness (Phase 2)Active Not RecruitingNCT05309668What this trial is testingPharmacokinetics, Safety and Efficacy of the Selumetinib Granule Formulation in Children Aged ≥1 to <7 Years With NF1-related Symptomatic, Inoperable PNWho this might be right forNeurofibromatosis Type 1 AstraZeneca 36
Testing effectiveness (Phase 2)Study completedNCT01673009What this trial is testingPhase II Study of Gleevec/Imatinib Mesylate (STI-571, NCS 716051) in Neurofibromatosis (NF1) Patients With Plexiform NeurofibromasWho this might be right forNeurofibromatosis Indiana University 36
Early research (Phase 1)Study completedNCT01031901What this trial is testingTopical Rapamycin Therapy to Alleviate Cutaneous Manifestations of Tuberous Sclerosis Complex (TSC) and Neurofibromatosis I (NF1)Who this might be right forTuberous SclerosisNeurofibromatosesAngiofibroma+1 more The University of Texas Health Science Center, Houston 52
Not applicableStudy completedNCT01595139What this trial is testingMicroRNAs in Patients With Neurofibromatosis Type 1Who this might be right forGliomaNeurofibromatosis Type 1 Ann & Robert H Lurie Children's Hospital of Chicago 9
Not applicableStudy completedNCT02479360What this trial is testingReliability of Functional Outcome Measures in Neurofibromatosis 1Who this might be right forNeurofibromatosis 1, NF1 Guy's and St Thomas' NHS Foundation Trust 49
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07131722What this trial is testingStudy to Determine Optimal Dose, Evaluate the Efficacy and Safety of PRG-N-01 in Patients With Neurofibromatosis Type IIWho this might be right forNeurofibromatosis Type IINF2 PRG Science & Technology Co., Ltd. 25
Not applicableLooking for participantsNCT07088991What this trial is testingClinical and Demographic Characteristics of Adult p Atients With NEurofibromatosis in RUSsiaWho this might be right forNeurofibromatosis AstraZeneca 200
Not applicableStudy completedNCT05377008What this trial is testingIntervention Effectiveness on the Neurocognitive Functioning of Children and Adolescents With Neurofibromatosis Type 1Who this might be right forNeurocognitive DeficitMental Health ImpairmentNeurofibromatosis 1 Virginia Commonwealth University 38
Very early researchStudy completedNCT01880749What this trial is testingExploring the Activity of RAD001 in Vestibular Schwannomas and MeningiomasWho this might be right forNeurofibromatosis Type 2Vestibular SchwannomasMeningiomas NYU Langone Health 5
Early research (Phase 1)Looking for participantsNCT02390752What this trial is testingPhase I Trial of TURALIO(R) (Pexidartinib, PLX3397) in Children and Young Adults With Refractory Leukemias and Refractory Solid Tumors Including Neurofibromatosis Type 1 (NF1) Associated Plexiform Neurofibromas (PN) and Tenosynovial Giant Cell Tumor ...Who this might be right forNeurofibroma, PlexiformPrecursor Cell Lymphoblastic Leukemia-LymphomaLeukemia, Promyelocytic, Acute+1 more National Cancer Institute (NCI) 54
Not applicableStudy completedNCT01904448What this trial is testingAuditory Brainstem Implantation in Young ChildrenWho this might be right forDevelopmental Cochlear Nerve DeficiencyAcquired Cochlear Nerve DeficiencyCochlear Aplasia+2 more University of North Carolina, Chapel Hill 5
Testing effectiveness (Phase 2)Study completedNCT01490476What this trial is testingEfficacy and Safety Study of RAD001 in the Growth of the Vestibular Schwannoma(s) in Neurofibromatosis 2 (NF2) PatientsWho this might be right forNeurofibromatosis 2 Assistance Publique - Hôpitaux de Paris 10
Not applicableStudy completedNCT03406208What this trial is testingResiliency Training for Adults With Neurofibromatosis Via Live VideoconferencingWho this might be right forNeurofibromatosesNeurofibromatosis 1Neurofibromatosis 2+1 more Massachusetts General Hospital 228
Not applicableNot Yet RecruitingNCT06834438What this trial is testingGene Therapy for Neurofibromatosis Type 2 (NF2) with ST002Who this might be right forNF2 Deficiency Cancer Institute and Hospital, Chinese Academy of Medical Sciences 9
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07708285What this trial is testingLuvometinib in Combination With Serplulimab for NF2-Related TumorsWho this might be right forNF2-related SchwannomatosisNF2Neurofibromatosis Type 2+2 more Beijing Tiantan Hospital 30
Large-scale testing (Phase 3)Looking for participantsNCT04166409What this trial is testingThe Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade GliomaWho this might be right forLow Grade AstrocytomaLow Grade GliomaMetastatic Low Grade Astrocytoma+3 more National Cancer Institute (NCI) 170
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06763315What this trial is testingLow-dose Selumetinib for the Treatment of Plexiform Neurofibromas in Chinese ChildrenWho this might be right forPlexiform Neurofibromas (PN) West China Hospital 50
Testing effectiveness (Phase 2)Study completedNCT03090971What this trial is testingUse of Topical Liquid Diclofenac Following Laser Microporation of Cutaneous Neurofibromas in Patients With NF1Who this might be right forNeurofibromatosis 1Cutaneous Neurofibroma Fundação Educacional Serra dos Órgãos 7