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Results for “Neurofibromatosis 1”

267 trials

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Showing 20 of 267 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT03190915
What this trial is testing

Trametinib in Treating Patients With Relapsed or Refractory Juvenile Myelomonocytic Leukemia

Who this might be right for
Juvenile Myelomonocytic LeukemiaNeurofibromatosis Type 1
National Cancer Institute (NCI) 10
Testing effectiveness (Phase 2)Active Not RecruitingNCT02407405
What this trial is testing

MEK 1/2 Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) in Adults With Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas

Who this might be right for
Neurofibromatosis 1 (NF1)Plexiform Neurofibromas (PN)
National Cancer Institute (NCI) 36
Not applicableActive Not RecruitingNCT04759781
What this trial is testing

MElanoma Research Lymph Node Prediction Implementation National_001

Who this might be right for
Melanoma
SkylineDx 1,820
Not applicableStudy completedNCT04991428
What this trial is testing

Mechanism of Action of Transcranial Direct Current Stimulation in Neurofibromatosis Type 1

Who this might be right for
Neurofibromatosis 1
University of Manchester 31
Early research (Phase 1)Study completedNCT01031901
What this trial is testing

Topical Rapamycin Therapy to Alleviate Cutaneous Manifestations of Tuberous Sclerosis Complex (TSC) and Neurofibromatosis I (NF1)

Who this might be right for
Tuberous SclerosisNeurofibromatosesAngiofibroma+1 more
The University of Texas Health Science Center, Houston 52
Testing effectiveness (Phase 2)Not Yet RecruitingNCT05253131
What this trial is testing

Trial of Selumetinib and Bromodomain Inhibitor With Durvalumab for Sarcomas

Who this might be right for
MPNSTNF1Sarcoma
University of Alabama at Birmingham 41
Not applicableStudy completedNCT02246231
What this trial is testing

Effect of Implant Position on Magnetic Resonance Image Distortion

Who this might be right for
Neurofibromatosis Type 2
Manchester University NHS Foundation Trust 5
Not applicableUnknownNCT03757247
What this trial is testing

Prevalence of Constitutional Mismatch-repair Deficiency Among Suspected Neurofibromatosis Type 1/Legius Syndrome Children Without a Malignancy and Without a NF1 or SPRED1 Mutation

Who this might be right for
Neurofibromatosis Type 1
Medical University Innsbruck 670
Early research (Phase 1)Not Yet RecruitingNCT06934928
What this trial is testing

Assessing the Efficacy of Repeat, Monthly Treatments of Alexandrite Laser for NF1-associated Cutaneous Neurofibromas (cNFs)

Who this might be right for
Neurofibromatosis 1 (NF1)Neurofibromatosis Type I
Massachusetts General Hospital 10
Not applicableLooking for participantsNCT06379230
What this trial is testing

A Retrospective Study on Epidemiological Characteristics of Chinese NF1 Patients in Real World (PROMISE)

Who this might be right for
Neurofibromatosis 1Plexiform Neurofibroma
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University 2,000
Testing effectiveness (Phase 2)Ended earlyNCT01345136
What this trial is testing

Study of RAD001 for Treatment of NF2-related Vestibular Schwannoma

Who this might be right for
Neurofibromatosis Type 2Neuroma, Acoustic
Jonsson Comprehensive Cancer Center 4
Not applicableLooking for participantsNCT00598351
What this trial is testing

Natural History Study of Patients With Neurofibromatosis Type 2

Who this might be right for
Neurofibromatosis
National Institute of Neurological Disorders and Stroke (NINDS) 269
Testing effectiveness (Phase 2)WithdrawnNCT05825365
What this trial is testing

Selumetinib in Chinese Paediatric With Post-operative NF1-PNs, PhaseⅡ, Double-Blinded, Placebo-Controlled Study

Who this might be right for
Neurofibromatosis Type 1Plexiform NeurofibromasPost-operative
AstraZeneca
Testing effectiveness (Phase 2)Looking for participantsNCT05180825
What this trial is testing

Pediatric Low Grade Glioma - MEKinhibitor TRIal vs Chemotherapy

Who this might be right for
Grade 1 GliomaMixed Glio-neuronal TumorsPleomorphic Xanthoastrocytoma
University Hospital, Strasbourg, France 134
Testing effectiveness (Phase 2)Study completedNCT03433183
What this trial is testing

SARC031: MEK Inhibitor Selumetinib (AZD6244) in Combination With the mTOR Inhibitor Sirolimus for Patients With Malignant Peripheral Nerve Sheath Tumors

Who this might be right for
Malignant Peripheral Nerve Sheath TumorsNeurofibromatosis 1
Sarcoma Alliance for Research through Collaboration 21
Not applicableUnknownNCT02078401
What this trial is testing

Ophthalmological Screening and Follow-up of Optic Pathway Gliomas in Children With Neurofibromatosis Type 1.

Who this might be right for
Neurofibromatosis Type 1
Universitaire Ziekenhuizen KU Leuven 200
Not applicableStudy completedNCT02422732
What this trial is testing

Functional Imaging and Reading Deficit in Children With NF1

Who this might be right for
Neurofibromatosis Type 1
University Hospital, Toulouse 25
Testing effectiveness (Phase 2)Study completedNCT03231306
What this trial is testing

Phase II Study of Binimetinib in Children and Adults With NF1 Plexiform Neurofibromas

Who this might be right for
Neurofibromatosis Type 1Plexiform Neurofibroma
University of Alabama at Birmingham 45
Early research (Phase 1)Study completedNCT04730583
What this trial is testing

Tolerability of Device Based Therapies for Neurofibromatosis Type 1 Cutaneous Neurofibromas

Who this might be right for
Cutaneous Neurofibroma
Massachusetts General Hospital 34
Early research (Phase 1)Study completedNCT02952937
What this trial is testing

Bioequivalence Study of Two Formulations of Pregabalin CR(Controlled-release) Table 300 mg

Who this might be right for
Healthy
GL Pharm Tech Corporation 24
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