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Results for “Neurofibromatosis 1 and 2 (NF1 and NF2)”

54 trials

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Showing 20 of 54 results

Testing effectiveness (Phase 2)Not Yet RecruitingNCT07131722
What this trial is testing

Study to Determine Optimal Dose, Evaluate the Efficacy and Safety of PRG-N-01 in Patients With Neurofibromatosis Type II

Who this might be right for
Neurofibromatosis Type IINF2
PRG Science & Technology Co., Ltd. 25
Very early researchStudy completedNCT01880749
What this trial is testing

Exploring the Activity of RAD001 in Vestibular Schwannomas and Meningiomas

Who this might be right for
Neurofibromatosis Type 2Vestibular SchwannomasMeningiomas
NYU Langone Health 5
Testing effectiveness (Phase 2)Study completedNCT01490476
What this trial is testing

Efficacy and Safety Study of RAD001 in the Growth of the Vestibular Schwannoma(s) in Neurofibromatosis 2 (NF2) Patients

Who this might be right for
Neurofibromatosis 2
Assistance Publique - Hôpitaux de Paris 10
Not applicableStudy completedNCT03406208
What this trial is testing

Resiliency Training for Adults With Neurofibromatosis Via Live Videoconferencing

Who this might be right for
NeurofibromatosesNeurofibromatosis 1Neurofibromatosis 2+1 more
Massachusetts General Hospital 228
Not applicableNot Yet RecruitingNCT06834438
What this trial is testing

Gene Therapy for Neurofibromatosis Type 2 (NF2) with ST002

Who this might be right for
NF2 Deficiency
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 9
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07708285
What this trial is testing

Luvometinib in Combination With Serplulimab for NF2-Related Tumors

Who this might be right for
NF2-related SchwannomatosisNF2Neurofibromatosis Type 2+2 more
Beijing Tiantan Hospital 30
Testing effectiveness (Phase 2)Study completedNCT02934256
What this trial is testing

Icotinib Study for Patients With Neurofibromatosis Type 2 (NF2) and NF2-Related Tumors

Who this might be right for
Vestibular SchwannomaNeurofibromatosis Type 2
Li Peng 10
Not applicableLooking for participantsNCT00598351
What this trial is testing

Natural History Study of Patients With Neurofibromatosis Type 2

Who this might be right for
Neurofibromatosis
National Institute of Neurological Disorders and Stroke (NINDS) 269
Testing effectiveness (Phase 2)Ended earlyNCT03095248
What this trial is testing

Trial of Selumetinib in Patients With Neurofibromatosis Type II Related Tumors

Who this might be right for
Neurofibromatosis 2Vestibular SchwannomaMeningioma+2 more
Children's Hospital Medical Center, Cincinnati 10
Testing effectiveness (Phase 2)Study completedNCT04283669
What this trial is testing

Phase 2 Clinical Trial of Crizotinib for Children and Adults With Neurofibromatosis Type 2 and Progressive Vestibular Schwannomas

Who this might be right for
Neurofibromatosis 2Progressive Vestibular Schwannoma (VS)
University of Alabama at Birmingham 12
Not applicableStudy completedNCT02435628
What this trial is testing

Relationship Between Psychosocial Factors, Health Literacy, Quality of Life and Satisfaction With Medical Visits in Adults With NF

Who this might be right for
Neurofibromatosis
Massachusetts General Hospital 86
Testing effectiveness (Phase 2)Study completedNCT00004437
What this trial is testing

Phase II Study of the Multichannel Auditory Brain Stem Implant for Deafness Following Surgery for Neurofibromatosis 2

Who this might be right for
Neurofibromatosis 2
FDA Office of Orphan Products Development
Testing effectiveness (Phase 2)Study completedNCT00589784
What this trial is testing

Phase II Trial of Sunitinib (SU011248) in Patients With Recurrent or Inoperable Meningioma

Who this might be right for
CNS CancerMeningiomaIntracranial Hemangiopericytoma+2 more
Memorial Sloan Kettering Cancer Center 50
Not applicableStudy completedNCT03672838
What this trial is testing

A Single Center Pilot Study to Assess the Intra-observer Reliability of Measuring Muscle Strength Using a Hand Held Dynamometer in Children and Adults With Neurofibromatosis Type 1 (NF1) and Type 2 (NF2)

Who this might be right for
Neurofibromatosis 1 and 2 (NF1 and NF2)
NYU Langone Health 33
Testing effectiveness (Phase 2)Study completedNCT01207687
What this trial is testing

Bevacizumab for Symptomatic Vestibular Schwannoma in Neurofibromatosis Type 2 (NF2)

Who this might be right for
Vestibular SchwannomaNeurofibromatosis Type 2
National Cancer Institute (NCI) 14
Large-scale testing (Phase 3)Ended earlyNCT03710564
What this trial is testing

Study of Safety and Efficacy of Brolucizumab 6 mg Dosed Every 4 Weeks Compared to Aflibercept 2 mg Dosed Every 4 Weeks in Patients With Retinal Fluid Despite Frequent Anti-VEGF Injections

Who this might be right for
Age-Related Macular Degeneration
Novartis Pharmaceuticals 535
Very early researchStudy completedNCT00863122
What this trial is testing

Concentration and Activity of Lapatinib in Vestibular Schwannomas

Who this might be right for
Vestibular SchwannomaNF2Neurofibromatosis 2+2 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 26
Testing effectiveness (Phase 2)Looking for participantsNCT04374305
What this trial is testing

Innovative Trial for Understanding the Impact of Targeted Therapies in NF2-Related Schwannomatosis (INTUITT-NF2)

Who this might be right for
Neurofibromatosis Type 2Vestibular SchwannomaNon-vestibular Schwannoma+2 more
Scott R. Plotkin, MD, PhD 109
Very early researchEnded earlyNCT02282917
What this trial is testing

Exploratory Evaluation of AR-42 Histone Deacetylase Inhibitor in the Treatment of Vestibular Schwannoma and Meningioma

Who this might be right for
Vestibular SchwannomaMeningiomaAcoustic Neuroma+1 more
Massachusetts Eye and Ear Infirmary 7
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07713745
What this trial is testing

Platform Research for Innovative Medicines in NF2-SWN (PRIME-NF2)

Who this might be right for
Neurofibromatosis Type 2Vestibular SchwannomaNon-vestibular Schwannoma+4 more
Beijing Tiantan Hospital 200
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