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Results for “Neurofibromatosis Type 1 (NF1)”

270 trials

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Showing 20 of 270 results

Early research (Phase 1)Study completedNCT02211768
What this trial is testing

Transformation of Plexiform Neurofibromas to Malignant Peripheral Nerve Sheath Tumors in Neurofibromatosis Type 1

Who this might be right for
NeurofibromatosisMPNST
National Cancer Institute (NCI) 10
Testing effectiveness (Phase 2)Ended earlyNCT01968590
What this trial is testing

Vitamin D Supplementation for Adults With Neurofibromatosis Type 1 (NF1)

Who this might be right for
Neurofibromatosis Type 1 (NF1)
University of Utah 26
Testing effectiveness (Phase 2)Study completedNCT05005845
What this trial is testing

NFX-179 Topical Gel Treatment for Adults With Neurofibromatosis 1 (NF1) and Cutaneous Neurofibromas (cNF)

Who this might be right for
Cutaneous NeurofibromaNeurofibromatosis 1
NFlection Therapeutics, Inc. 199
Large-scale testing (Phase 3)Study completedNCT02471339
What this trial is testing

Acceptance and Commitment Training for Adolescents and Young Adults With Neurofibromatosis Type 1, Plexiform Neurofibromas, and Chronic Pain

Who this might be right for
Neurofibromatosis Type 1Plexiform Neurofibromas
National Cancer Institute (NCI) 66
Testing effectiveness (Phase 2)Study completedNCT02934256
What this trial is testing

Icotinib Study for Patients With Neurofibromatosis Type 2 (NF2) and NF2-Related Tumors

Who this might be right for
Vestibular SchwannomaNeurofibromatosis Type 2
Li Peng 10
Testing effectiveness (Phase 2)Study completedNCT01158651
What this trial is testing

Everolimus for Children With NF1 Chemotherapy-Refractory Radiographic Progressive Low Grade Gliomas

Who this might be right for
Glioma
University of Alabama at Birmingham 23
Testing effectiveness (Phase 2)Looking for participantsNCT07237100
What this trial is testing

Mirdametinib in Patients With Advanced NF1-mutant Melanoma

Who this might be right for
Advanced Unresectable MelanomaMetastatic Melanoma
Kevin Kim, MD 10
Testing effectiveness (Phase 2)Study completedNCT04435665
What this trial is testing

NFX-179 Topical Gel Treatment in Adults With Neurofibromatosis 1 (NF1) and Cutaneous Neurofibromas (cNF)

Who this might be right for
Neurofibromatosis 1Cutaneous Neurofibroma
NFlection Therapeutics, Inc. 48
Not applicableEnded earlyNCT05683678
What this trial is testing

US Selumetinib Registry

Who this might be right for
Neurofibromatosis Type 1Plexiform Neurofibromas
Alexion Pharmaceuticals, Inc. 37
Not applicableUnknownNCT01218152
What this trial is testing

Microarray CGH Analysis of Circulating Tumoral Plasma DNA in NF1 Patients With MPNSTs

Who this might be right for
Neurofibromatosis Type 1
KU Leuven 20
Testing effectiveness (Phase 2)Ended earlyNCT02728388
What this trial is testing

Photodynamic Therapy for Benign Dermal Neurofibromas- Phase II

Who this might be right for
NEUROFIBROMATOSIS 1
Donald Basel 30
Testing effectiveness (Phase 2)Study completedNCT01419639
What this trial is testing

Phase II Study of Everolimus (RAD001) in Children and Adults With Neurofibromatosis Type 2

Who this might be right for
Neurofibromatosis Type II
NYU Langone Health 10
Large-scale testing (Phase 3)Active Not RecruitingNCT04924608
What this trial is testing

Efficacy and Safety of Selumetinib in Adults With NF1 Who Have Symptomatic, Inoperable Plexiform Neurofibromas

Who this might be right for
Neurofibromatosis 1Plexiform Neurofibroma (PN)
AstraZeneca 145
Not applicableStudy completedNCT04561765
What this trial is testing

Innovation in the Treatment of Persistent Pain in Adults With NF1: Implementation of the iCanCope Mobile Application- Clinical Trial

Who this might be right for
Neurofibromatosis 1Chronic Pain
Yale University 122
Large-scale testing (Phase 3)Ended earlyNCT02256124
What this trial is testing

Effect of Lamotrigine on Cognition in NF1

Who this might be right for
Neurofibromatosis Type 1
Erasmus Medical Center 41
Very early researchStudy completedNCT01275586
What this trial is testing

Study of Tasigna®/Nilotinib (AMN107) in Neurofibromatosis (NF1) Patients With Plexiform Neurofibromas

Who this might be right for
NeurofibromatosisNF1Neurofibromas
Indiana University 6
Testing effectiveness (Phase 2)Active Not RecruitingNCT01362803
What this trial is testing

AZD6244 Hydrogen Sulfate for Children With Nervous System Tumors

Who this might be right for
Neurofibromatosis 1Neurofibromatosis Type 1NF1+1 more
National Cancer Institute (NCI) 99
Not applicableNo Longer AvailableNCT02589912
What this trial is testing

Compassionate Use Arm - ABI541 ABI for 10 NF2 Patients

Who this might be right for
Neurofibromatosis Type 2Severe Profound Sensorineural Hearing Loss
Massachusetts Eye and Ear Infirmary
Not applicableEnded earlyNCT01736267
What this trial is testing

Auditory Brainstem Implant (ABI) in Adult Non-Neurofibromatosis Type 2 Subjects

Who this might be right for
Bilateral Hearing Loss for Causes Other Than Tumors
Massachusetts Eye and Ear Infirmary 3
Testing effectiveness (Phase 2)Active Not RecruitingNCT01089101
What this trial is testing

Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma

Who this might be right for
Low Grade GliomaRecurrent Childhood Pilocytic AstrocytomaRecurrent Neurofibromatosis Type 1+3 more
National Cancer Institute (NCI) 217
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