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Results for “Neurofibromatosis Type 2”

91 trials

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Showing 20 of 91 results

Very early researchStudy completedNCT00863122
What this trial is testing

Concentration and Activity of Lapatinib in Vestibular Schwannomas

Who this might be right for
Vestibular SchwannomaNF2Neurofibromatosis 2+2 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 26
Testing effectiveness (Phase 2)Active Not RecruitingNCT02407405
What this trial is testing

MEK 1/2 Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) in Adults With Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas

Who this might be right for
Neurofibromatosis 1 (NF1)Plexiform Neurofibromas (PN)
National Cancer Institute (NCI) 36
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07131722
What this trial is testing

Study to Determine Optimal Dose, Evaluate the Efficacy and Safety of PRG-N-01 in Patients With Neurofibromatosis Type II

Who this might be right for
Neurofibromatosis Type IINF2
PRG Science & Technology Co., Ltd. 25
Testing effectiveness (Phase 2)Looking for participantsNCT06541847
What this trial is testing

A Phase 2, Open-Label Study to Evaluate the Safety and Effects of HLX-1502 in Patients With Neurofibromatosis Type 1

Who this might be right for
Neurofibromatosis Type 1
Healx Limited 25
Not applicableLooking for participantsNCT00598351
What this trial is testing

Natural History Study of Patients With Neurofibromatosis Type 2

Who this might be right for
Neurofibromatosis
National Institute of Neurological Disorders and Stroke (NINDS) 269
Post-approval studies (Phase 4)WithdrawnNCT00588172
What this trial is testing

Genetic Variation in OCT1 and Response to Metformin

Who this might be right for
Type 2 Diabetes
Mayo Clinic
Testing effectiveness (Phase 2)WithdrawnNCT02986919
What this trial is testing

Study of CPI-0610 in Patients With Malignant Peripheral Nerve Sheath Tumors

Who this might be right for
Peripheral Nerve Tumors
University of Texas Southwestern Medical Center
Testing effectiveness (Phase 2)Looking for participantsNCT06188741
What this trial is testing

Selumetinib for the Prevention of Plexiform Neurofibroma Growth in NF Type 1

Who this might be right for
Neurofibromatosis 1Plexiform Neurofibroma
University of Alabama at Birmingham 200
Testing effectiveness (Phase 2)Study completedNCT04283669
What this trial is testing

Phase 2 Clinical Trial of Crizotinib for Children and Adults With Neurofibromatosis Type 2 and Progressive Vestibular Schwannomas

Who this might be right for
Neurofibromatosis 2Progressive Vestibular Schwannoma (VS)
University of Alabama at Birmingham 12
Testing effectiveness (Phase 2)Active Not RecruitingNCT03962543
What this trial is testing

MEK Inhibitor Mirdametinib (PD-0325901) in Patients With Neurofibromatosis Type 1 Associated Plexiform Neurofibromas

Who this might be right for
Plexiform NeurofibromaNeurofibromatosis Type 1 (NF1)
SpringWorks Therapeutics, Inc., a healthcare company of Merck KGaA, Darmstadt, Germany 114
Not applicableUnknownNCT05685836
What this trial is testing

89Zr-Bevacizumab PET/CT Imaging in NF2 Patients

Who this might be right for
Neurofibromatosis 2
Leiden University Medical Center 15
Not applicableEnded earlyNCT01736267
What this trial is testing

Auditory Brainstem Implant (ABI) in Adult Non-Neurofibromatosis Type 2 Subjects

Who this might be right for
Bilateral Hearing Loss for Causes Other Than Tumors
Massachusetts Eye and Ear Infirmary 3
Testing effectiveness (Phase 2)Active Not RecruitingNCT03079999
What this trial is testing

Study of Aspirin in Patients With Vestibular Schwannoma

Who this might be right for
Vestibular SchwannomaAcoustic NeuromaNeurofibromatosis 2
Massachusetts Eye and Ear Infirmary 97
Not applicableLooking for participantsNCT03050268
What this trial is testing

Familial Investigations of Childhood Cancer Predisposition

Who this might be right for
Acute LeukemiaAdenomatous PolyposisAdrenocortical Carcinoma+43 more
St. Jude Children's Research Hospital 1,500
Large-scale testing (Phase 3)Looking for participantsNCT04166409
What this trial is testing

The Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Glioma

Who this might be right for
Low Grade AstrocytomaLow Grade GliomaMetastatic Low Grade Astrocytoma+3 more
National Cancer Institute (NCI) 170
Testing effectiveness (Phase 2)Ended earlyNCT02177825
What this trial is testing

Study of Imatinib Mesylate in Neurofibromatosis Type I Patients Aged 2 to 21 With Plexiform Neurofibromas

Who this might be right for
Plexiform Neurofibromas
St. Justine's Hospital 5
Testing effectiveness (Phase 2)Study completedNCT00973739
What this trial is testing

Lapatinib Study for Children and Adults With Neurofibromatosis Type 2 (NF2) and NF2-Related Tumors

Who this might be right for
Neurofibromatosis 2Vestibular Schwannoma
NYU Langone Health 21
Large-scale testing (Phase 3)Ended earlyNCT05130866
What this trial is testing

Efficacy and Safety of REC-2282 in Patients With Progressive Neurofibromatosis Type 2 (NF2) Mutated Meningiomas

Who this might be right for
Neurofibromatosis Type 2
Recursion Pharmaceuticals Inc. 25
Testing effectiveness (Phase 2)Study completedNCT02934256
What this trial is testing

Icotinib Study for Patients With Neurofibromatosis Type 2 (NF2) and NF2-Related Tumors

Who this might be right for
Vestibular SchwannomaNeurofibromatosis Type 2
Li Peng 10
Early research (Phase 1)Looking for participantsNCT05873686
What this trial is testing

Clinical Study of NXP900 in Subjects With Advanced Cancers

Who this might be right for
Advanced Solid TumorNSCLC (Non-small Cell Lung Cancer)Renal Cancer+3 more
Nuvectis Pharma, Inc. 140
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