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Results for “Neurofibromatosis Type I”

267 trials

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Showing 20 of 267 results

Not applicableUnknownNCT01777451
What this trial is testing

Whole Body Magnetic Resonance Imaging With Diffusion Weighted Imaging : Potential Role in Neurofibromatosis

Who this might be right for
Whole Body ImagingMagnetic Resonance ImagingNeurofibromatosis 1+2 more
Universitaire Ziekenhuizen KU Leuven 30
Early research (Phase 1)Ended earlyNCT04800822
What this trial is testing

PF-07284892 in Participants With Advanced Solid Tumors

Who this might be right for
Solid Tumor
Pfizer 53
Testing effectiveness (Phase 2)Study completedNCT00846430
What this trial is testing

Medical Treatment of "High-Risk" Neurofibromas

Who this might be right for
Neurofibromatosis 1
Corewell Health West 9
Very early researchStudy completedNCT01275586
What this trial is testing

Study of Tasigna®/Nilotinib (AMN107) in Neurofibromatosis (NF1) Patients With Plexiform Neurofibromas

Who this might be right for
NeurofibromatosisNF1Neurofibromas
Indiana University 6
Not applicableStudy completedNCT01595139
What this trial is testing

MicroRNAs in Patients With Neurofibromatosis Type 1

Who this might be right for
GliomaNeurofibromatosis Type 1
Ann & Robert H Lurie Children's Hospital of Chicago 9
Testing effectiveness (Phase 2)Looking for participantsNCT04750928
What this trial is testing

Cyclin-Dependent Kinase (CDK)4/6 Inhibitor Abemaciclib for Neurofibromatosis Type I (NF1) Related Atypical Neurofibromas

Who this might be right for
Neurofibromatosis 1
National Cancer Institute (NCI) 55
Very early researchStudy completedNCT00863122
What this trial is testing

Concentration and Activity of Lapatinib in Vestibular Schwannomas

Who this might be right for
Vestibular SchwannomaNF2Neurofibromatosis 2+2 more
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins 26
Testing effectiveness (Phase 2)Active Not RecruitingNCT02407405
What this trial is testing

MEK 1/2 Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) in Adults With Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform Neurofibromas

Who this might be right for
Neurofibromatosis 1 (NF1)Plexiform Neurofibromas (PN)
National Cancer Institute (NCI) 36
Not applicableLooking for participantsNCT05361811
What this trial is testing

Acceptance and Commitment Therapy for Caregivers of Children With a RASopathy: An Internal Pilot Feasibility Study and Follow-up Randomized Controlled Trial

Who this might be right for
Neurofibromatosis 1Noonan SyndromeLegius Syndrome+2 more
National Cancer Institute (NCI) 70
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07131722
What this trial is testing

Study to Determine Optimal Dose, Evaluate the Efficacy and Safety of PRG-N-01 in Patients With Neurofibromatosis Type II

Who this might be right for
Neurofibromatosis Type IINF2
PRG Science & Technology Co., Ltd. 25
Testing effectiveness (Phase 2)Study completedNCT00030264
What this trial is testing

Combination Chemotherapy in Treating Patients With Neurofibromatosis and Progressive Plexiform Neurofibromas

Who this might be right for
Neurofibromatosis Type 1Precancerous Condition
Children's Hospital of Philadelphia 23
Testing effectiveness (Phase 2)Looking for participantsNCT06541847
What this trial is testing

A Phase 2, Open-Label Study to Evaluate the Safety and Effects of HLX-1502 in Patients With Neurofibromatosis Type 1

Who this might be right for
Neurofibromatosis Type 1
Healx Limited 25
Not applicableStudy completedNCT01702922
What this trial is testing

Relationship Stressors in Parents of Children With Cancer or Neurofibromatosis Type 1 (NF1)

Who this might be right for
Parents of Children With CancerParents of Children With NF1Parents of Children With Neurofibromatosis Type I
National Cancer Institute (NCI) 262
Not applicableLooking for participantsNCT00598351
What this trial is testing

Natural History Study of Patients With Neurofibromatosis Type 2

Who this might be right for
Neurofibromatosis
National Institute of Neurological Disorders and Stroke (NINDS) 269
Early research (Phase 1)Study completedNCT03649165
What this trial is testing

Evaluate Bioavailability and Food Effect of Selumetinib (AZD6244) in Healthy Male Participants

Who this might be right for
Neurofibromatosis Type 1 (NF1)-Related Plexiform Neurofibromas (PNs)Healthy Participants
AstraZeneca 24
Testing effectiveness (Phase 2)Ended earlyNCT03504501
What this trial is testing

Synaptic Plasticity and Cognitive Function in RASopathies

Who this might be right for
Impaired Synaptic PlasticityImpaired Cognition
Technical University of Munich 16
Post-approval studies (Phase 4)WithdrawnNCT00588172
What this trial is testing

Genetic Variation in OCT1 and Response to Metformin

Who this might be right for
Type 2 Diabetes
Mayo Clinic
Testing effectiveness (Phase 2)Study completedNCT03326388
What this trial is testing

Intermittent Dosing Of Selumetinib In Childhood NF1 Associated Tumours

Who this might be right for
Neurofibromatosis Type 1Plexiform NeurofibromaOptic Nerve Glioma
Great Ormond Street Hospital for Children NHS Foundation Trust 14
Not applicableLooking for participantsNCT07088991
What this trial is testing

Clinical and Demographic Characteristics of Adult p Atients With NEurofibromatosis in RUSsia

Who this might be right for
Neurofibromatosis
AstraZeneca 200
Testing effectiveness (Phase 2)Study completedNCT04481035
What this trial is testing

Antioxidant Therapy With N-acetylcysteine for Learning and Motor Behavior in Children With Neurofibromatosis Type 1

Who this might be right for
Neurofibromatosis 1
Children's Hospital Medical Center, Cincinnati 5
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