Not applicableUnknownNCT02505412What this trial is testingSubtle Myocardial Deformation Abnormalities in Asymptomatic Nf-1 PatientsWho this might be right forNeurofibromatosis Type 1 Tel-Aviv Sourasky Medical Center 50
Not applicableStudy completedNCT05377008What this trial is testingIntervention Effectiveness on the Neurocognitive Functioning of Children and Adolescents With Neurofibromatosis Type 1Who this might be right forNeurocognitive DeficitMental Health ImpairmentNeurofibromatosis 1 Virginia Commonwealth University 38
Not applicableStudy completedNCT03310996What this trial is testingNon-invasive Stimulation in Neurofibromatosis Type 1Who this might be right forNeurofibromatosis 1 University of Manchester 16
Not applicableWithdrawnNCT03332030What this trial is testingStem Cells in NF1 Patients With Tumors of the Central Nervous SystemWho this might be right forNeurofibromatosis Type 1Tumors of the Central Nervous System Roger Packer
Early research (Phase 1)Study completedNCT03649165What this trial is testingEvaluate Bioavailability and Food Effect of Selumetinib (AZD6244) in Healthy Male ParticipantsWho this might be right forNeurofibromatosis Type 1 (NF1)-Related Plexiform Neurofibromas (PNs)Healthy Participants AstraZeneca 24
Not applicableStudy completedNCT01058330What this trial is testingEffects of Physical Training on Bone and Muscle Quality, Muscle Strength, and Motor Coordination in Children With NF1Who this might be right forNeurofibromatosis Type 1 Shriners Hospitals for Children 36
Not applicableStudy completedNCT07327164What this trial is testingPrecision Medicine for Neurocutaneous Syndromes in Western ChinaWho this might be right forNeurocutaneous SyndromesNeurofibromatosis Type 1 (NF1)Tuberous Sclerosis Complex (TSC)+2 more West China Hospital 1,200
Not applicableTemporarily pausedNCT06934928What this trial is testingAssessing the Efficacy of Repeat, Monthly Treatments of Alexandrite Laser for NF1-associated Cutaneous Neurofibromas (cNFs)Who this might be right forNeurofibromatosis 1 (NF1)Neurofibromatosis Type I Massachusetts General Hospital 10
Testing effectiveness (Phase 2)Study completedNCT04435665What this trial is testingNFX-179 Topical Gel Treatment in Adults With Neurofibromatosis 1 (NF1) and Cutaneous Neurofibromas (cNF)Who this might be right forNeurofibromatosis 1Cutaneous Neurofibroma NFlection Therapeutics, Inc. 48
Not applicableLooking for participantsNCT06507748What this trial is testingEvaluate the Feasibility of a Physiologic Biomarker to Assess Pain and Other Sensory Problems Using Pupillometry in Participants With Neurofibromatosis Type 1 (NF1)Who this might be right forNeurofibromatosis Type 1 National Cancer Institute (NCI) 70
Not applicableStudy completedNCT03298438What this trial is testingStudy About Annoucement of the Diagnosis of Neurofibromatosis 1 in de Novo FormsWho this might be right forNeurofibromatosis 1Diagnoses DiseasePost Traumatic Stress Disorder University Hospital, Brest 31
Testing effectiveness (Phase 2)Looking for participantsNCT05331105What this trial is testingHL-085 in Adults With Neurofibromatosis Type 1 (NF1) and Inoperable Plexiform NeurofibromasWho this might be right forNeurofibromatosis 1Plexiform Neurofibromas Shanghai Kechow Pharma, Inc. 70
Not applicableUnknownNCT06379230What this trial is testingA Retrospective Study on Epidemiological Characteristics of Chinese NF1 Patients in Real World (PROMISE)Who this might be right forNeurofibromatosis 1Plexiform Neurofibroma Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University 2,000
Not applicableUnknownNCT02436746What this trial is testingThe Cognitive Variability in NF1 and TSC Monozygotic TwinsWho this might be right forNeurofibromatosis Type ITuberous Sclerosis Complex Erasmus Medical Center 116
Not applicableStudy completedNCT02298270What this trial is testingResiliency Training for Patients With Neurofibromatosis Via Videoconferencing With SkypeWho this might be right forNeurofibromatosisNeurofibromatosis INeurofibromatosis 2+1 more Massachusetts General Hospital 65
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07743554What this trial is testingCombination of Avutometinib and Defactinib for Treatment of Relapsed, Refractory, Metastatic, or Unresectable Malignant Peripheral Nerve Sheath TumorWho this might be right forMPNST (Malignant Peripheral Nerve Sheath Tumor) Girish Dhall, MD 23
Not applicableStudy completedNCT00844129What this trial is testingSpinal Abnormalities in Neurofibromatosis Type 1 (NF1)Who this might be right forNeurofibromatosis Type 1 University of Utah 112
Not applicableActive Not RecruitingNCT05388370What this trial is testingPASS of Paediatric Patients Initiating SelumetinibWho this might be right forNeurofibromatosis Type 1 AstraZeneca 124
Testing effectiveness (Phase 2)Active Not RecruitingNCT01089101What this trial is testingSelumetinib in Treating Young Patients With Recurrent or Refractory Low Grade GliomaWho this might be right forLow Grade GliomaRecurrent Childhood Pilocytic AstrocytomaRecurrent Neurofibromatosis Type 1+3 more National Cancer Institute (NCI) 217
Testing effectiveness (Phase 2)Study completedNCT02096471What this trial is testingMEK Inhibitor PD-0325901 Trial in Adolescents and Adults With NF1Who this might be right forNeurofibromatosis Type 1 and Growing or Symptomatic, Inoperable PN University of Alabama at Birmingham 19