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Results for “Neuromyelitis Optica Spectrum Disorder Relapse”

20 trials

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Showing 20 of 20 results

Testing effectiveness (Phase 2)WithdrawnNCT05909943
What this trial is testing

Efficacy and Safety of Ruxolitinib in Neuromyelitis Optica Spectrum Disorders

Who this might be right for
Neuromyelitis Optica Spectrum Disorder Relapse
Tianjin Medical University General Hospital
Early research (Phase 1)Looking for participantsNCT06869278
What this trial is testing

LCAR-AIO CAR-T Cells for Treating Relapsed/Refractory Neurological Autoimmune Diseases

Who this might be right for
Multiple Sclerosis (MS)Neuromyelitis Optica Spectrum Disease (NMOSD)Anti-Myelin Oligodendrocyte Glycoprotein-IgG Associated Disorders (MOGAD)+1 more
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 37
Early research (Phase 1)WithdrawnNCT03605238
What this trial is testing

Treatment of Relapsed and/or Refractory AQP4-IgG Seropositive NMOSD by Tandem CAR T Cells Targeting CD19 and CD20

Who this might be right for
Neuromyelitis Optica Spectrum Disorder
Chinese PLA General Hospital
Large-scale testing (Phase 3)Ended earlyNCT04155424
What this trial is testing

The Safety and Activity of Eculizumab in Pediatric Participants With Relapsing Neuromyelitis Optica Spectrum Disorder

Who this might be right for
Neuromyelitis OpticaNeuromyelitis Optica Spectrum Disorder
Alexion Pharmaceuticals, Inc. 5
Post-approval studies (Phase 4)UnknownNCT02021825
What this trial is testing

Efficacy and Safety of Mitoxantrone in Patients With Refractory Neuromyelitis Optica and Spectrum Disorders

Who this might be right for
Neuromyelitis OpticaNeuromyelitis Optica Spectrum Disorders
Xuanwu Hospital, Beijing 50
Large-scale testing (Phase 3)Ended earlyNCT01892345
What this trial is testing

Controlled Trial of Eculizumab in AQP4 Antibody-positive Participants With NMO (PREVENT Study)

Who this might be right for
Neuromyelitis OpticaNeuromyelitis Optica Spectrum Disorder
Alexion Pharmaceuticals, Inc. 143
Not applicableLooking for participantsNCT05204459
What this trial is testing

MS-ResearchBiomarkerS

Who this might be right for
Multiple SclerosisMultiple Sclerosis, Relapsing-RemittingMultiple Sclerosis, Primary Progressive+8 more
Cedars-Sinai Medical Center 1,000
Post-approval studies (Phase 4)Not Yet RecruitingNCT07010302
What this trial is testing

Rituximab Versus Ravulizumab, Inebilizumab, Satralizumab, and Eculizumab in NMOSD

Who this might be right for
NMOSD
Massachusetts General Hospital 160
Large-scale testing (Phase 3)Study completedNCT02003144
What this trial is testing

An Open Label Extension Trial of Eculizumab in Relapsing NMO Patients

Who this might be right for
Neuromyelitis OpticaNeuromyelitis Optica Spectrum Disorder
Alexion Pharmaceuticals, Inc. 119
Testing effectiveness (Phase 2)Study completedNCT02893111
What this trial is testing

Efficacy and Safety of Bortezomib as add-on Treatment in Relapsing Neuromyelitis Optica Spectrum Disorder

Who this might be right for
Neuromyelitis Optica Spectrum Disorder
Tianjin Medical University General Hospital 5
Not applicableEnded earlyNCT04131764
What this trial is testing

Diagnosis of ON With or Without MS or NMOSD

Who this might be right for
Multiple SclerosisNeuromyelitis Optica Spectrum Disorder AttackNeuromyelitis Optica Spectrum Disorder Relapse+2 more
Jagannadha R Avasarala 112
Large-scale testing (Phase 3)Not Yet RecruitingNCT07132398
What this trial is testing

Slow vs. Rapid Glucocorticoids Tapering With Inebilizumab in NMOSD

Who this might be right for
Neuromyelitis Optica (NMO)Neuromyelitis Optica Spectrum Disorders (NMOSD)
Tianjin Medical University General Hospital 170
Large-scale testing (Phase 3)Looking for participantsNCT05349006
What this trial is testing

Azathioprine in MOGAD

Who this might be right for
Central Nervous System InflammationMOG-IgG Associated Disease
Hospices Civils de Lyon 126
Very early researchNot Yet RecruitingNCT07392528
What this trial is testing

Universal Chimeric Antigen Receptor T-Cell （UCAR T-cell） Therapy Targeting CD19/ BCMA（QT-019C） in Patients With r/ r Neurological Autoimmune Diseases

Who this might be right for
Neuromyelitis Optica Spectrum DisordersMultiple SclerosisMyasthenia Gravis
Tianjin Huanhu Hospital 15
Large-scale testing (Phase 3)Study completedNCT04201262
What this trial is testing

An Efficacy and Safety Study of Ravulizumab in Adult Participants With NMOSD

Who this might be right for
Neuromyelitis OpticaNeuromyelitis Optica Spectrum Disorder
Alexion Pharmaceuticals, Inc. 58
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06561009
What this trial is testing

Safety and Efficacy of BAFFR CART for Relapsed/ Refractory Neuromyelitis Optica Spectrum Disorder

Who this might be right for
Neuromyelitis Optica Spectrum Disorder
Tianjin Medical University General Hospital 20
Very early researchLooking for participantsNCT06939166
What this trial is testing

Universal Chimeric Antigen Receptor T-Cell （UCAR T-cell） Therapy Targeting CD19/B Cell Maturation Antigen （CD19/BCMA） in Patients With r/r Neurological Autoimmune Diseases

Who this might be right for
Neuromyelitis Optica Spectrum DisordersMyasthenia GravisMultiple Sclerosis+2 more
Tianjin Huanhu Hospital 12
Large-scale testing (Phase 3)Study completedNCT03002038
What this trial is testing

Comparison of Clinical Effects of Azathioprine and Rituximab NMO-SD Patients

Who this might be right for
Neuromyelitis Optica Spectrum Disorder
Isfahan University of Medical Sciences 86
Very early researchLooking for participantsNCT04561557
What this trial is testing

Safety and Efficacy of CT103A Cells for Relapsed/Refractory Antibody-associated Inflammatory Diseases of the Nervous System

Who this might be right for
Autoimmune DiseasesAutoimmune Diseases of the Nervous SystemNeuromyelitis Optica Spectrum Disorder+7 more
Tongji Hospital 36
Early research (Phase 1)Study completedNCT02276963
What this trial is testing

Ublituximab for Acute Neuromyelitis Optica (NMO) Relapses

Who this might be right for
Neuromyelitis OpticaNeuromyelitis Optica Spectrum Disorder
Johns Hopkins University 6