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Results for “Neurotrophic Keratitis”

46 trials

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Showing 20 of 46 results

Testing effectiveness (Phase 2)Study completedNCT04957758
What this trial is testing

Phase 2 Clinical Trial to Evaluate OC-01 Nasal Spray in Subjects With Neurotrophic Keratopathy

Who this might be right for
Neurotrophic Keratopathy
Oyster Point Pharma, Inc. 113
Testing effectiveness (Phase 2)Looking for participantsNCT07568730
What this trial is testing

A Multicenter, Randomized, Vehicle-Controlled, Double-Masked to Open-Label Study to Evaluate the Safety and Efficacy of Lacripep in Subjects With Neurotrophic Keratitis

Who this might be right for
Neurotrophic Keratitis
TearSolutions, Inc. 54
Not applicableUnknownNCT04573647
What this trial is testing

OCT Evaluation of Neurotrophic Ulcer Following Treatment With Oxervate

Who this might be right for
Neurotrophic UlcerNeurotrophic KeratitisNeurotrophic Corneal Ulcer+1 more
Sight Medical Doctors PLLC 10
Testing effectiveness (Phase 2)Study completedNCT04276558
What this trial is testing

REC 0/0559 Eye Drops for Treatment of Moderate and Severe Neurotrophic Keratitis in Adult Patients

Who this might be right for
Neurotrophic Keratitis
RECORDATI GROUP 108
Large-scale testing (Phase 3)Looking for participantsNCT05555589
What this trial is testing

Assessment of the Safety and Efficacy of 0.1% RGN-259 Ophthalmic Solution for the Treatment of NK: SEER-2

Who this might be right for
Neurotrophic Keratopathy
ReGenTree, LLC 70
Not applicableLooking for participantsNCT04700657
What this trial is testing

The Prevalence of Hypoesthesia Related Keratitis in Ocular Graft Vs. Host Disease (GVHD) Patients

Who this might be right for
Ocular GVHD
Indiana University 30
Not applicableUnknownNCT06412718
What this trial is testing

Validation of Human Drugs Target of Repurposed Drugs and Novel Therapies

Who this might be right for
Rare DiseasesAniridiaNeurotrophic Keratopathy+5 more
IRCCS Ospedale San Raffaele 274
Not applicableTemporarily pausedNCT05758753
What this trial is testing

QST for Corneal Nerve Function

Who this might be right for
Corneal DiseaseNeuropathyDry Eye Disease+1 more
Tufts Medical Center 108
Post-approval studies (Phase 4)WithdrawnNCT06411145
What this trial is testing

Open-label Trial to Evaluate Efficacy and Safety of rhNGF on Corneal Thickness Via AS-OCT in Neurotrophic Keratitis

Who this might be right for
Neurotrophic KeratitisNeurotrophic KeratopathyCorneal Ulcer
Dompé Farmaceutici S.p.A
Not applicableEnded earlyNCT05809245
What this trial is testing

Corneal Neurotization as a Treatment for Neurotrophic Keratopathy

Who this might be right for
Neurotrophic Corneal UlcerNeurotrophic KeratitisCranial Nerve V Diseases
Stanford University 4
Not applicableNot Yet RecruitingNCT07073729
What this trial is testing

Corneal Neurotization vs. Cenergermin for Neurotrophic Keratitis: A Pilot Study

Who this might be right for
Neurotrophic Keratitis
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's 10
Testing effectiveness (Phase 2)Study completedNCT02592330
What this trial is testing

Limbal Stem Cell Deficiency (LSCD) Treatment With Cultivated Stem Cell (CALEC) Graft

Who this might be right for
Limbal Stem Cell Deficiency
Massachusetts Eye and Ear Infirmary 23
Testing effectiveness (Phase 2)Study completedNCT04909450
What this trial is testing

Study to Evaluate the Safety and Efficacy of CSB-001 Ophthalmic Solution 0.1% in Neurotrophic Keratitis Subjects

Who this might be right for
Neurotrophic Keratitis
Claris Biotherapeutics, Inc. 131
Not applicableStudy completedNCT05552261
What this trial is testing

DEFENDO Long Term Follow-up Study in Stage 1 NK Patients

Who this might be right for
Neurotrophic Keratitis
Dompé Farmaceutici S.p.A 24
Not applicableEnded earlyNCT06364657
What this trial is testing

Differences in Corneal Structure and Function in Patients With Sjogrens vs. Non-Sjogrens Dry Eye

Who this might be right for
Sjogren's SyndromeDry EyeNeurotrophic Keratitis
Johns Hopkins University 13
Testing effectiveness (Phase 2)Looking for participantsNCT06975748
What this trial is testing

A Phase II Study of STSP-0902 Ophthalmic Solution in Patients With Neurotrophic Keratitis

Who this might be right for
Neurotrophic Keratitis
Staidson (Beijing) Biopharmaceuticals Co., Ltd 48
Testing effectiveness (Phase 2)Study completedNCT07120308
What this trial is testing

To Evaluate the Efficacy and Safety of ZKY001 Eye Drops in the Treatment of Corneal Epithelial Defects Caused by Neurotrophic Keratitis

Who this might be right for
Corneal Epithelial Defect
Zhaoke (Guangzhou) Ophthalmology Pharmaceutical Ltd. 28
Not applicableUnknownNCT05566717
What this trial is testing

An Investigator-Initiated Study to Assess the Association of Diabetic Retinopathy Severity Scale (DRSS) With Level of Decreased Corneal Sensitivity

Who this might be right for
Diabetic RetinopathyNeurotrophic Keratitis
Medical Center Ophthalmology Associates 50
Not applicableNot Yet RecruitingNCT07694817
What this trial is testing

Clinical Predictors of Visual Outcome in Patients Affected With Ocular Surface Diseases

Who this might be right for
Neurotrophic KeratopathyExposure KeratopathyLimbal Stem Cell Deficiency (LSCD)+3 more
IRCCS San Raffaele 1,000
Testing effectiveness (Phase 2)Looking for participantsNCT06999733
What this trial is testing

A Study Comparing KB801 Verse Placebo in Patients With Stage 2 or 3 Neurotrophic Keratitis

Who this might be right for
Neurotrophic Keratitis
Krystal Biotech, Inc. 60
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