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Results for “Neurotrophic Keratopathy”

46 trials

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Showing 20 of 46 results

Large-scale testing (Phase 3)Study completedNCT01794312
What this trial is testing

Efficacy and Safety Assessment of T4020 Versus Vehicule in Patients With Chronic Neurotrophic Keratitis or Corneal Ulcer

Who this might be right for
KeratitisCorneal Ulcer
Laboratoires Thea 152
Not applicableNot Yet RecruitingNCT07073729
What this trial is testing

Corneal Neurotization vs. Cenergermin for Neurotrophic Keratitis: A Pilot Study

Who this might be right for
Neurotrophic Keratitis
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's 10
Not applicableStudy completedNCT04820010
What this trial is testing

Topical Insulin - Utility and Results in Neurotrophic Keratopathy in Stages 2 and 3

Who this might be right for
Corneal UlcerCorneal PerforationCorneal Epithelium Defect+1 more
Centro Hospitalar de Vila Nova de Gaia/Espinho, E.P.E. 20
Post-approval studies (Phase 4)WithdrawnNCT06411145
What this trial is testing

Open-label Trial to Evaluate Efficacy and Safety of rhNGF on Corneal Thickness Via AS-OCT in Neurotrophic Keratitis

Who this might be right for
Neurotrophic KeratitisNeurotrophic KeratopathyCorneal Ulcer
Dompé Farmaceutici S.p.A
Large-scale testing (Phase 3)WithdrawnNCT05321251
What this trial is testing

Topical Insulin Drops for the Treatment of Neurotrophic Keratopathy.

Who this might be right for
Neurotrophic Keratitis
University of Alberta
Post-approval studies (Phase 4)Looking for participantsNCT06964269
What this trial is testing

Use of Acthar Gel Single-Dose Pre-Filled SelfJectTM Injector in Patients With Moderate-Severe Keratitis and Autoimmune Disease

Who this might be right for
Autoimmune DiseasesDry EyeNeurotrophic Keratitis
Toyos Clinic 20
Testing effectiveness (Phase 2)Study completedNCT01756456
What this trial is testing

Evaluation of Safety and Efficacy of rhNGF in Patients With Stage 2 and 3 Neurotrophic Keratitis.

Who this might be right for
Neurotrophic KeratitisKeratitisCorneal Ulcer
Dompé Farmaceutici S.p.A 174
Not applicableLooking for participantsNCT04700657
What this trial is testing

The Prevalence of Hypoesthesia Related Keratitis in Ocular Graft Vs. Host Disease (GVHD) Patients

Who this might be right for
Ocular GVHD
Indiana University 30
Not applicableEnded earlyNCT05809245
What this trial is testing

Corneal Neurotization as a Treatment for Neurotrophic Keratopathy

Who this might be right for
Neurotrophic Corneal UlcerNeurotrophic KeratitisCranial Nerve V Diseases
Stanford University 4
Testing effectiveness (Phase 2)Study completedNCT04276558
What this trial is testing

REC 0/0559 Eye Drops for Treatment of Moderate and Severe Neurotrophic Keratitis in Adult Patients

Who this might be right for
Neurotrophic Keratitis
RECORDATI GROUP 108
Post-approval studies (Phase 4)Looking for participantsNCT07502378
What this trial is testing

Effect of Acoltremon Ophthalmic Solution 0.003% on Signs and Symptoms of Ocular Surface Disease in Stage I Neurotrophic Keratopathy Patients With Tear Deficiency

Who this might be right for
Ocular Surface DiseaseNeurotrophic Keratopathy Stage 1
University of South Florida 50
Early research (Phase 1)Study completedNCT06597422
What this trial is testing

STSP-0902 Ophthalmic Solution in Healthy Subjects

Who this might be right for
Neurotrophic Keratitis
Staidson (Beijing) Biopharmaceuticals Co., Ltd 82
Testing effectiveness (Phase 2)Looking for participantsNCT06975748
What this trial is testing

A Phase II Study of STSP-0902 Ophthalmic Solution in Patients With Neurotrophic Keratitis

Who this might be right for
Neurotrophic Keratitis
Staidson (Beijing) Biopharmaceuticals Co., Ltd 48
Not applicableUnknownNCT05566717
What this trial is testing

An Investigator-Initiated Study to Assess the Association of Diabetic Retinopathy Severity Scale (DRSS) With Level of Decreased Corneal Sensitivity

Who this might be right for
Diabetic RetinopathyNeurotrophic Keratitis
Medical Center Ophthalmology Associates 50
Testing effectiveness (Phase 2)Looking for participantsNCT07568730
What this trial is testing

A Multicenter, Randomized, Vehicle-Controlled, Double-Masked to Open-Label Study to Evaluate the Safety and Efficacy of Lacripep in Subjects With Neurotrophic Keratitis

Who this might be right for
Neurotrophic Keratitis
TearSolutions, Inc. 54
Not applicableUnknownNCT05940376
What this trial is testing

Topical Insulin in Neurotrophic Keratopathy After Diabetic Vitrectomy

Who this might be right for
Corneal UlcerNeurotrophic Corneal UlcerDiabetes Mellitus
Benha University 30
Testing effectiveness (Phase 2)Looking for participantsNCT06919081
What this trial is testing

Efficacy of Topical Mesenchymal Stromal Cell Secretome for Ocular Surface Disease

Who this might be right for
Persistent Corneal Epithelial DefectCorneal Epithelial Disorders
University of Illinois at Chicago 24
Large-scale testing (Phase 3)Ended earlyNCT02600429
What this trial is testing

Assessment of the Safety and Efficacy Study of RGN-259 Ophthalmic Solutions for Neurotrophic Keratopathy : SEER-1

Who this might be right for
Neurotrophic Keratopathy
ReGenTree, LLC 18
Not applicableStudy completedNCT04293549
What this trial is testing

An 8-week Follow-up to Evaluate the Renewal of Corneal Nerves Structure and Function in Patients With Neurotrophic Keratopathy Treated With Recombinant Human Nerve Growth Factor (rhNGF) Eyedrops

Who this might be right for
Neurotrophic Keratopathy
G. d'Annunzio University 18
Post-approval studies (Phase 4)UnknownNCT06331910
What this trial is testing

Efficacy and Safety of Topical Insulin for Neurotrophic Corneal Ulcers

Who this might be right for
Neurotrophic Keratopathy
Assiut University 14
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