Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Newly Diagnosed High Grade Glioma (HGG)”

22 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 22 results

Testing effectiveness (Phase 2)Looking for participantsNCT05099003
What this trial is testing

The Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)

Who this might be right for
Malignant Glioma
National Cancer Institute (NCI) 132
Testing effectiveness (Phase 2)Active Not RecruitingNCT03581292
What this trial is testing

Veliparib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Malignant Glioma Without H3 K27M or BRAFV600 Mutations

Who this might be right for
Anaplastic AstrocytomaGlioblastomaMalignant Glioma
National Cancer Institute (NCI) 38
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07439172
What this trial is testing

Pre-Radiation Chemotherapy for Newly Diagnosed High-Grade Glioma.

Who this might be right for
High Grade GliomasGlioblastomaAstrocytoma+1 more
The Cooper Health System 70
Testing effectiveness (Phase 2)Looking for participantsNCT06161974
What this trial is testing

Study of Olutasidenib and Temozolomide in HGG

Who this might be right for
High Grade GliomaAstrocytomaAstrocytoma, Grade III+16 more
Rigel Pharmaceuticals 60
Early research (Phase 1)WithdrawnNCT02598011
What this trial is testing

The Safety of Toca 511, a Retroviral Replicating Vector, Combined With Toca FC in Subjects With Newly Diagnosed High Grade Glioma Receiving Standard of Care

Who this might be right for
Newly Diagnosed High Grade Glioma (HGG)
Tocagen Inc.
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07206849
What this trial is testing

Study of Tovorafenib in High-Grade Glioma and Diffuse Intrinsic Pontine Glioma (DIPG)

Who this might be right for
High Grade Glioma (HGG) of the Brain With BRAF AberrationHigh Grade Glioma (III or IV)Diffuse Intrinsic Pontine Glioma+4 more
Nationwide Children's Hospital 79
Early research (Phase 1)Looking for participantsNCT06305910
What this trial is testing

CD200AR-L and Allogeneic Tumor Lysate Vaccine Immunotherapy for Recurrent HGG and Newly Diagnosed DMG/DIPG in Children and Young Adults

Who this might be right for
Diffuse Midline Glioma, H3 K27M-MutantRecurrent High Grade Glioma
OX2 Therapeutics 24
Testing effectiveness (Phase 2)Looking for participantsNCT05096481
What this trial is testing

PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma

Who this might be right for
High Grade GliomaDiffuse Intrinsic Pontine GliomaRecurrent Medulloblastoma
Nationwide Children's Hospital 120
Very early researchLooking for participantsNCT06072586
What this trial is testing

BDTX-1535 in Recurrent High-Grade Glioma (rHGG) and Newly Diagnosed Glioblastoma (nGBM) Participants With EGFR Alterations or Fusions

Who this might be right for
High Grade GliomaGlioblastoma
St. Joseph's Hospital and Medical Center, Phoenix 82
Not applicableEnded earlyNCT02039778
What this trial is testing

Stem Cell Radiotherapy and Temozolomide for Newly Diagnosed High-grade Glioma

Who this might be right for
GlioblastomaMalignant GliomaBrain Tumors+1 more
Beth Israel Medical Center 4
Not applicableStudy completedNCT02082119
What this trial is testing

Hypofractionated IMRT With Temozolomide for HGG

Who this might be right for
Glioma
Istituto Clinico Humanitas 82
Testing effectiveness (Phase 2)Study completedNCT04497142
What this trial is testing

Effect of Perampanel on Peritumoral Hyperexcitability in HGG

Who this might be right for
Glioma, MalignantSurgerySeizures
Dana-Farber Cancer Institute 12
Testing effectiveness (Phase 2)Study completedNCT02099487
What this trial is testing

Hypofractionated Imrt (Vmat-Ra) For Elderly Patients With Newly Diagnosed High Grade Glioma

Who this might be right for
Glioma
Istituto Clinico Humanitas 20
Testing effectiveness (Phase 2)Looking for participantsNCT05843253
What this trial is testing

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

Who this might be right for
High Grade GliomaDiffuse Intrinsic Pontine GliomaAnaplastic Astrocytoma+7 more
Nationwide Children's Hospital 120
Very early researchActive Not RecruitingNCT03893487
What this trial is testing

Fimepinostat in Treating Brain Tumors in Children and Young Adults

Who this might be right for
Diffuse Intrinsic Pontine GliomaRecurrent Anaplastic AstrocytomaRecurrent Glioblastoma+2 more
Sabine Mueller, MD, PhD 30
Not applicableUnknownNCT02239952
What this trial is testing

HGG-TCP (High Grade Glioma - Tumor Concentrations of Protein Kinase Inhibitors)

Who this might be right for
CancerHigh-grade Glioma
Amsterdam UMC, location VUmc 15
Testing effectiveness (Phase 2)Active Not RecruitingNCT03919071
What this trial is testing

Dabrafenib Combined With Trametinib After Radiation Therapy in Treating Patients With Newly-Diagnosed High-Grade Glioma

Who this might be right for
Anaplastic AstrocytomaAnaplastic Astrocytoma, Not Otherwise SpecifiedAnaplastic Ganglioglioma+5 more
National Cancer Institute (NCI) 58
Testing effectiveness (Phase 2)Ended earlyNCT02607124
What this trial is testing

A Phase I/II Study of Ribociclib,a CDK4/6 Inhibitor, Following Radiation Therapy

Who this might be right for
High Grade GliomaDiffuse Intrinsic Pontine GliomaBithalamic High Grade Glioma
Children's Hospital Medical Center, Cincinnati 11
Early research (Phase 1)Study completedNCT03355794
What this trial is testing

Ribociclib and Everolimus Following Radiation Therapy in Children With Newly Diagnosed Non-biopsied Diffuse Pontine Gliomas (DIPG) and RB+ Biopsied DIPG and High Grade Gliomas (HGG)

Who this might be right for
Diffuse Intrinsic Pontine GliomaMalignant Glioma of BrainHigh Grade Glioma+4 more
Children's Hospital Medical Center, Cincinnati 19
Early research (Phase 1)Study completedNCT06665724
What this trial is testing

Clinical Trial Evaluating Safety of 5-Aminolevulinic Acid (5-ALA) Combined With CV01 Delivery of Ultrasound for Sonodynamic Therapy (SDT) in Patients With Newly Diagnosed High-Grade Glioma (HGG) Prior to Resection and Standard Adjuvant Therapy (ALA SDT GLIOMA 401)

Who this might be right for
Anaplastic Astrocytoma (AA)Anaplastic Oligodendroglioma (AO)Glioblastoma (GBM)
Universität Münster 16
Load More Results