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Results for “Newly Diagnosed Pediatric Pontine Glioma”

19 trials

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Showing 19 of 19 results

Early research (Phase 1)Ended earlyNCT03396575
What this trial is testing

Brain Stem Gliomas Treated With Adoptive Cellular Therapy During Focal Radiotherapy Recovery Alone or With Dose-intensified Temozolomide (Phase I)

Who this might be right for
Diffuse Intrinsic Pontine Glioma (DIPG)Brain Stem Glioma
University of Florida 11
Testing effectiveness (Phase 2)Looking for participantsNCT05843253
What this trial is testing

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

Who this might be right for
High Grade GliomaDiffuse Intrinsic Pontine GliomaAnaplastic Astrocytoma+7 more
Nationwide Children's Hospital 120
Early research (Phase 1)Active Not RecruitingNCT03389802
What this trial is testing

Phase I Study of APX005M in Pediatric Central Nervous System Tumors

Who this might be right for
Glioblastoma MultiformeHigh-grade Astrocytoma Not Otherwise Specified (NOS)CNS Primary Tumor, Not Otherwise Specified (NOS)+3 more
Pediatric Brain Tumor Consortium 32
Early research (Phase 1)Looking for participantsNCT06894979
What this trial is testing

Testing the Addition of an Anti-Cancer Drug, AZD1390, During Radiation Therapy for Newly Diagnosed High Grade Glioma, Diffuse Midline Glioma, or Diffuse Intrinsic Pontine Glioma

Who this might be right for
Childhood AstrocytomaChildhood Diffuse Intrinsic Pontine GliomaChildhood Diffuse Midline Glioma+2 more
Children's Oncology Group 54
Testing effectiveness (Phase 2)Active Not RecruitingNCT06521567
What this trial is testing

Cobolimab Plus Dostarlimab in Pediatric and Young Adult Participants With Cancer

Who this might be right for
MelanomaHodgkin LymphomaHigh and Low Grade Glioma+9 more
GlaxoSmithKline 83
Testing effectiveness (Phase 2)Looking for participantsNCT05099003
What this trial is testing

The Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG)

Who this might be right for
Malignant Glioma
National Cancer Institute (NCI) 132
Early research (Phase 1)Study completedNCT01130077
What this trial is testing

A Pilot Study of Glioma Associated Antigen Vaccines in Conjunction with Poly-ICLC in Pediatric Gliomas

Who this might be right for
Newly Diagnosed Pediatric Pontine GliomaNewly Diagnosed Pediatric High Grade GliomaRecurrent Pediatric High Grade Glioma+1 more
James Felker 60
Testing effectiveness (Phase 2)Looking for participantsNCT05096481
What this trial is testing

PEP-CMV Vaccine Targeting CMV Antigen to Treat Newly Diagnosed Pediatric HGG and DIPG and Recurrent Medulloblastoma

Who this might be right for
High Grade GliomaDiffuse Intrinsic Pontine GliomaRecurrent Medulloblastoma
Nationwide Children's Hospital 120
Early research (Phase 1)Study completedNCT03696355
What this trial is testing

Study of GDC-0084 in Pediatric Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma or Diffuse Midline Gliomas

Who this might be right for
Brain and Central Nervous System Tumors
St. Jude Children's Research Hospital 27
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07206849
What this trial is testing

Study of Tovorafenib in High-Grade Glioma and Diffuse Intrinsic Pontine Glioma (DIPG)

Who this might be right for
High Grade Glioma (HGG) of the Brain With BRAF AberrationHigh Grade Glioma (III or IV)Diffuse Intrinsic Pontine Glioma+4 more
Nationwide Children's Hospital 79
Testing effectiveness (Phase 2)Ended earlyNCT03690869
What this trial is testing

REGN2810 in Pediatric Patients With Relapsed, Refractory Solid, or Central Nervous System (CNS) Tumors and Safety and Efficacy of REGN2810 in Combination With Radiotherapy in Pediatric Patients With Newly Diagnosed or Recurrent Glioma

Who this might be right for
Relapsed Solid TumorRefractory Solid TumorRelapsed Central Nervous System Tumor+3 more
Regeneron Pharmaceuticals 57
Early research (Phase 1)Study completedNCT01393912
What this trial is testing

PDGFR Inhibitor Crenolanib in Children/Young Adults With Diffuse Intrinsic Pontine Glioma or Recurrent High-Grade Glioma

Who this might be right for
Diffuse Intrinsic Pontine GliomaProgressive or Refractory High-Grade Glioma
St. Jude Children's Research Hospital 55
Not applicableLooking for participantsNCT05839379
What this trial is testing

Targeted Pediatric High-Grade Glioma Therapy

Who this might be right for
High Grade GliomaDiffuse Intrinsic Pontine GliomaAnaplastic Astrocytoma+6 more
Nationwide Children's Hospital 350
Early research (Phase 1)Study completedNCT03178032
What this trial is testing

Oncolytic Adenovirus, DNX-2401, for Naive Diffuse Intrinsic Pontine Gliomas

Who this might be right for
Brainstem GliomaNeoadjuvant Therapy
Clinica Universidad de Navarra, Universidad de Navarra 12
Early research (Phase 1)Active Not RecruitingNCT04978727
What this trial is testing

A Pilot Study of SurVaxM in Children Progressive or Relapsed Medulloblastoma, High Grade Glioma, Ependymoma and Newly Diagnosed Diffuse Intrinsic Pontine Glioma

Who this might be right for
MedulloblastomaGlioblastoma MultiformeAnaplastic Astrocytoma+5 more
Children's Oncology Group 35
Testing effectiveness (Phase 2)Active Not RecruitingNCT04049669
What this trial is testing

Pediatric Trial of Indoximod With Chemotherapy and Radiation for Relapsed Brain Tumors or Newly Diagnosed DIPG

Who this might be right for
GlioblastomaMedulloblastomaEpendymoma+1 more
Theodore S. Johnson 130
Early research (Phase 1)Not Yet RecruitingNCT07076498
What this trial is testing

Engineered HSV-1 M032 for the Treatment of Children and Adults With Newly Diagnosed Diffuse Midline Glioma After Standard of Care Radiation

Who this might be right for
Glioma
M.D. Anderson Cancer Center 20
Early research (Phase 1)Ended earlyNCT03416530
What this trial is testing

ONC201 in Pediatric H3 K27M Gliomas

Who this might be right for
Diffuse Intrinsic Pontine GliomaGlioma, Malignant
Jazz Pharmaceuticals 134
Testing effectiveness (Phase 2)Looking for participantsNCT06161974
What this trial is testing

Study of Olutasidenib and Temozolomide in HGG

Who this might be right for
High Grade GliomaAstrocytomaAstrocytoma, Grade III+16 more
Rigel Pharmaceuticals 60