Early research (Phase 1)Ended earlyNCT00224965What this trial is testingEarly Tobacco Abstinence - 5Who this might be right forTobacco Use National Institute on Drug Abuse (NIDA) 140
Not applicableStudy completedNCT01036711What this trial is testingEffects of Nicotine on Cognitive Task Performance and Brain Activity as Measured by fMRIWho this might be right forNicotine DependenceDrug Abuse National Institute on Drug Abuse (NIDA) 249
Not applicableStudy completedNCT05658471What this trial is testingPharmacokinetics and Pharmacodynamics of Nicotine With Use of Standardized Research Electronic Cigarette (SREC)Who this might be right forNicotine DependenceTobacco ToxicityCardiovascular Risk Factors University of California, San Francisco 32
Not applicableStudy completedNCT01393301What this trial is testingIntegrated Treatment for Smoking Cessation & Anxiety in People With HIVWho this might be right forNicotine DependenceSymptoms of AnxietyHIV Massachusetts General Hospital 72
Not applicableStudy completedNCT02139930What this trial is testingProject 2: Strategies for Reducing Nicotine Content in CigarettesWho this might be right forNicotine DependenceTobacco Smoking Wake Forest University Health Sciences 1,250
Post-approval studies (Phase 4)Looking for participantsNCT06534047What this trial is testingTranscranial Magnetic Stimulation for Nicotine Dependence: An Effectiveness-Implementation TrialWho this might be right forTobacco Use DisorderPsychiatric DisorderNicotine Dependence Centre for Addiction and Mental Health 40
Large-scale testing (Phase 3)Study completedNCT01188018What this trial is testingTesting Counseling Styles to Motivate Smokers to QuitWho this might be right forSmokingTobacco UseNicotine Dependence University of Missouri, Kansas City 255
Not applicableLooking for participantsNCT04163081What this trial is testingThe INITIATE Study: Initiating Nicotine Dependence Treatment for Smokers Admitted to Emergency DepartmentsWho this might be right forNicotine Dependence, CigarettesNicotine Withdrawal Ottawa Heart Institute Research Corporation 1,208
Not applicableStudy completedNCT01505725What this trial is testingNicotine Reinforcement and Smoking-Cue Reactivity: Association With Genetic PolymorphismsWho this might be right forNicotine Dependence National Institute on Drug Abuse (NIDA) 92
Not applicableStudy completedNCT05897242What this trial is testingA Smartphone Application (ACT on Vaping) for Vaping Cessation in Young AdultsWho this might be right forNicotine DependenceNicotine AddictionNicotine Use Disorder+2 more Fred Hutchinson Cancer Center 61
Not applicableStudy completedNCT00973622What this trial is testingChanging Thought and Action in Tobacco Dependence With Transcranial Magnetic StimulationWho this might be right forTobacco Dependence University of Arkansas 66
Not applicableActive Not RecruitingNCT06910566What this trial is testingFactors Sustaining Tobacco Abstinence in Cancer Patients Treated With Radio-chemotherapy or RadiotherapyWho this might be right forSmoking CessationNicotine AddictionNicotine Dependence+2 more Centre Oscar Lambret 100
Not applicableLooking for participantsNCT06506162What this trial is testingAbuse Liability and Appeal of Oral Nicotine ProductsWho this might be right forNicotine Dependence University of Southern California 320
Testing effectiveness (Phase 2)Study completedNCT04696380What this trial is testingDo Flavors Increase the Addiction Potential of Nicotine?Who this might be right forNicotine Dependence University of Vermont 19
Not applicableStudy completedNCT05477342What this trial is testingReducing Nicotine Addiction in Adolescent SmokersWho this might be right forNicotine Dependence, CigarettesCessation, TobaccoCessation, Smoking+1 more Ministry of National Education, Turkey 103
Very early researchStudy completedNCT04535362What this trial is testingNicotine's Potential Abuse With MentholWho this might be right forNicotine Dependence Yale University 16
Not applicableStudy completedNCT01093599What this trial is testingTrial on the Effectiveness of Mindfulness Training for SmokersWho this might be right forNicotine Dependence University of Wisconsin, Madison 196
Not applicableStudy completedNCT03463837What this trial is testingIdentify Biomarkers of Tobacco Exposure and Nicotine Uptake From JUUL 5% in Adult SmokersWho this might be right forNicotine Dependence, Other Tobacco ProductTobacco UseSmoking, Tobacco Juul Labs, Inc. 90
Early research (Phase 1)WithdrawnNCT01784653What this trial is testingTrial of Computerized MET for Adolescent Substance UseWho this might be right forDrug AbuseAlcohol AbuseNicotine Dependence Boston Children's Hospital
Not applicableStudy completedNCT02102100What this trial is testingThe Effects of Menthol as Delivered by an Electronic Cigarette on the Desirability of Nicotine in Tobacco UsersWho this might be right forNicotine Dependence Yale University 57