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Results for “Niraparib”

195 trials

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Showing 20 of 195 results

Not applicableUnknownNCT05598788
What this trial is testing

Microsampling Approach for Monitoring of Kinase Inhibitor Targeted Therapies

Who this might be right for
Blood Concentrations of Nine Anti-cancer Drugs : Axitinib, Olaparib, regorafénib, Cabozantinib, Niraparib, Talazoparib, Palbociclib, Abemaciclib, Tucatinib
Rennes University Hospital 360
Early research (Phase 1)Study completedNCT02044120
What this trial is testing

ESP1/SARC025 Global Collaboration: A Phase I Study of a Combination of the PARP Inhibitor, Niraparib and Temozolomide and/or Irinotecan Patients With Previously Treated, Incurable Ewing Sarcoma

Who this might be right for
Ewing Sarcoma
Sarcoma Alliance for Research through Collaboration 34
Testing effectiveness (Phase 2)UnknownNCT05311579
What this trial is testing

Niraparib Plus Anlotinib for Recurrent Ovarian Cancer

Who this might be right for
Ovarian CarcinomaSurvival OutcomesAdverse Events+6 more
Lei Li 36
Not applicableStudy completedNCT04546373
What this trial is testing

Niraparib as Maintenance Therapy in Patients With Platinum Sensitive Recurrent Ovarian Cancer

Who this might be right for
Epithelial Ovarian CancerFallopian Tube CancerPrimary Peritoneal Cancer
Grupo Español de Investigación en Cáncer de Ovario 316
Testing effectiveness (Phase 2)Looking for participantsNCT05460000
What this trial is testing

A Phase II Randomized, Open Label Non-inferiority Study of NiraParib Maintenance After 3 vs. 6 Cycles of Platinum-based Chemotherapy in completeLy debUlked Advanced HRDpositive High-grade Ovarian Cancer patientS in First Line Therapy

Who this might be right for
Ovarian CancerFallopian Tube CancerPrimary Peritoneal Carcinoma+1 more
North Eastern German Society of Gynaecological Oncology 640
Early research (Phase 1)Study completedNCT03076203
What this trial is testing

Phase IB Trial of Radium-223 and Niraparib in Patients With Castrate Resistant Prostate Cancer (NiraRad)

Who this might be right for
Prostate Carcinoma Metastatic to the BoneStage IV Prostate AdenocarcinomaHormone-refractory Prostate Cancer
Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University 14
Testing effectiveness (Phase 2)Active Not RecruitingNCT04030559
What this trial is testing

Niraparib Before Surgery in Treating Patients With High Risk Localized Prostate Cancer and DNA Damage Response Defects

Who this might be right for
ATM Gene MutationBRCA1 Gene MutationBRCA2 Gene Mutation+14 more
Marc Dall'Era, MD 11
Testing effectiveness (Phase 2)Study completedNCT04080284
What this trial is testing

Trial of Maintenance With Niraparib- Uterine Serous Carcinoma

Who this might be right for
Endometrial CancerPapillary Serous Endometrial CarcinomaUterine Serous Carcinoma+2 more
Northwell Health 22
Large-scale testing (Phase 3)Active Not RecruitingNCT02655016
What this trial is testing

Niraparib (GSK3985771) Maintenance Treatment in Participants With Advanced Ovarian Cancer Following Response on Front-Line Platinum-Based Chemotherapy

Who this might be right for
Ovarian Neoplasms
Tesaro, Inc. 733
Early research (Phase 1)Study completedNCT02476552
What this trial is testing

Absorption, Metabolism, Excretion, and the Determination of Absolute Bioavailability of Niraparib in Subjects With Cancer

Who this might be right for
Cancer
Tesaro, Inc. 12
Early research (Phase 1)Study completedNCT03307785
What this trial is testing

Study of Niraparib, TSR-022, Bevacizumab, and Platinum-Based Doublet Chemotherapy in Combination With TSR-042

Who this might be right for
NeoplasmsMetastatic CancerAdvanced Cancer+4 more
Tesaro, Inc. 60
Testing effectiveness (Phase 2)Looking for participantsNCT04947254
What this trial is testing

Androgen Ablation Therapy With or Without Niraparib After Radiation Therapy for the Treatment of High-Risk Localized or Locally Advanced Prostate Cancer

Who this might be right for
Prostate CarcinomaStage IIC Prostate Cancer AJCC v8Stage III Prostate Cancer AJCC v8+4 more
M.D. Anderson Cancer Center 200
Testing effectiveness (Phase 2)Study completedNCT04284852
What this trial is testing

Niraparib Maintenance in Patients With Advanced Ovarian Cancer at Neoadjuvant Setting

Who this might be right for
Ovarian Cancer
The University of Hong Kong 20
Large-scale testing (Phase 3)UnknownNCT04679064
What this trial is testing

Trial on NIraparib-TSR-042 (Dostarlimab) vs Physician's Choice CHEmotherapy in Recurrent, Ovarian, Fallopian Tube or Primary Peritoneal Cancer Patients Not Candidate for Platinum Retreatment

Who this might be right for
Ovarian Cancer
Fondazione Policlinico Universitario Agostino Gemelli IRCCS 427
Testing effectiveness (Phase 2)Study completedNCT02354131
What this trial is testing

Niraparib Versus Niraparib-bevacizumab Combination in Women With Platinum-sensitive Epithelial Ovarian Cancer

Who this might be right for
Ovarian Cancer
Nordic Society of Gynaecological Oncology - Clinical Trials Unit 108
Testing effectiveness (Phase 2)UnknownNCT04395612
What this trial is testing

Niraparib Combined With Brivanib or Toripalimab in Patients With Cervical Cancer

Who this might be right for
Cervical Cancer
Chongqing University Cancer Hospital 38
Early research (Phase 1)Ended earlyNCT03944902
What this trial is testing

CB-839 in Combination With Niraparib in Platinum Resistant BRCA -Wild-type Ovarian Cancer Patients

Who this might be right for
Ovarian CancerResistant BRCA Wild-Type Ovarian Cancer
University of Alabama at Birmingham 1
Testing effectiveness (Phase 2)Looking for participantsNCT06747845
What this trial is testing

Maintenance Niraparib Plus Ipilimumab in Patients With Metastatic Pancreatic Adenocarcinoma Whose Disease Has Not Progressed on Platinum-Based Chemotherapy

Who this might be right for
Pancreatic Adenocarcinoma Metastatic
Abramson Cancer Center at Penn Medicine 68
Testing effectiveness (Phase 2)Study completedNCT03404960
What this trial is testing

Niraparib + Ipilimumab or Nivolumab in Progression Free Pancreatic Adenocarcinoma After Platinum-Based Chemotherapy

Who this might be right for
Pancreatic Adenocarcinoma
University of Pennsylvania 104
Testing effectiveness (Phase 2)Looking for participantsNCT05784012
What this trial is testing

Two-cohort Study of Niraparib and Dostarlimab Plus (Chemo)RadIotherapy in Locally-Advanced Head and Neck Squamous Cell Carcinoma

Who this might be right for
Head and Neck Squamous Cell Carcinoma
Grupo Español de Tratamiento de Tumores de Cabeza y Cuello 34
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