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Results for “Niraparib”

196 trials

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Showing 20 of 196 results

Early research (Phase 1)Study completedNCT01294735
What this trial is testing

Study of the Safety and Efficacy of MK-4827 Given With Temozolomide in Participants With Advanced Cancer (MK-4827-014 AM1)

Who this might be right for
Recurrence of Solid TumorGlioblastoma MultiformeMelanoma
Merck Sharp & Dohme LLC 19
Testing effectiveness (Phase 2)UnknownNCT05461690
What this trial is testing

Phase II Study of Niraparib in Metastatic TNBC Patients With Homologous Recombination Deficiency

Who this might be right for
Homologous Recombination DeficiencyTriple Negative Breast Cancer
Zhejiang Cancer Hospital 50
Testing effectiveness (Phase 2)Ended earlyNCT05169437
What this trial is testing

Niraparib in the Treatment of Patients With Advanced PALB2 Mutated Tumors

Who this might be right for
Solid TumorBreast TumorColon Tumor, Malignant+9 more
Tempus AI 22
Testing effectiveness (Phase 2)Ended earlyNCT05689021
What this trial is testing

CJNJ-67652000 and Prednisone for Treatment of Metastatic Castration-Resistant Prostate Cancer and SPOP Gene Mutations

Who this might be right for
Castration-Resistant Prostate CarcinomaMetastatic Prostate AdenocarcinomaStage IVB Prostate Cancer AJCC v8
Mayo Clinic 8
Testing effectiveness (Phase 2)Study completedNCT04288687
What this trial is testing

A Trial of Niraparib in Platinum-Sensitive Castration-Resistant Prostate Cancer With DNA Repair Defects

Who this might be right for
Prostate Adenocarcinoma
Abramson Cancer Center at Penn Medicine 11
Testing effectiveness (Phase 2)Active Not RecruitingNCT05870761
What this trial is testing

Combination Niraparib and Dostarlimab Therapy for Recurrent or Persistent Uterine Serous Carcinoma

Who this might be right for
Recurrent Endometrial Serous Adenocarcinoma
Casey Cosgrove 8
Testing effectiveness (Phase 2)Looking for participantsNCT04716686
What this trial is testing

Niraparib Monotherapy as Maintain and Recurrent Treatment of Endometrial Serous Carcinoma

Who this might be right for
Endometrial CarcinomaSerous Carcinoma
Shandong University 83
Early research (Phase 1)Ended earlyNCT02500901
What this trial is testing

Enzalutamide and Niraparib in the Treatment of Metastatic Castrate-Resistant Prostate Cancer (CRPC)

Who this might be right for
Metastatic Prostate Cancer
Paul Mathew, MD 2
Testing effectiveness (Phase 2)Active Not RecruitingNCT04592237
What this trial is testing

Cabazitaxel, Carboplatin, and Cetrelimab Followed by Niraparib With or Without Cetrelimab for the Treatment of Aggressive Variant Metastatic Prostate Cancer

Who this might be right for
Aggressive Variant Prostate CarcinomaCastration-Resistant Prostate CarcinomaMetastatic Prostate Carcinoma+3 more
M.D. Anderson Cancer Center 120
Early research (Phase 1)Active Not RecruitingNCT04577833
What this trial is testing

Comparative Formulations of Niraparib and Abiraterone Acetate (AA) in Men With Prostate Cancer

Who this might be right for
Prostatic Neoplasms
Janssen Research & Development, LLC 136
Testing effectiveness (Phase 2)Study completedNCT04080284
What this trial is testing

Trial of Maintenance With Niraparib- Uterine Serous Carcinoma

Who this might be right for
Endometrial CancerPapillary Serous Endometrial CarcinomaUterine Serous Carcinoma+2 more
Northwell Health 22
Testing effectiveness (Phase 2)Study completedNCT03207347
What this trial is testing

A Trial of Niraparib in BAP1 and Other DNA Damage Response (DDR) Deficient Neoplasms (UF-STO-ETI-001)

Who this might be right for
MesotheliomaUveal MelanomaRenal Cell Carcinoma+1 more
University of Florida 37
Testing effectiveness (Phase 2)WithdrawnNCT04895046
What this trial is testing

Maintenance Niraparib and Dostarlimab in Advanced Cholangiocarcinoma

Who this might be right for
HRDCholangiocarcinomaMetastatic Cancer
Walid Shaib, MD
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06258018
What this trial is testing

Niraparib and Temozolomide in Patients Glioblastoma

Who this might be right for
Glioma, Malignant
Armando Santoro, MD 86
Large-scale testing (Phase 3)UnknownNCT03705156
What this trial is testing

Clinical Trial Evaluating the Efficacy and Safety of ZL-2306 (Niraparib) in Ovarian Cancer Patient

Who this might be right for
Platinum-sensitive Relapsed Ovarian Cancer
Zai Lab (Shanghai) Co., Ltd. 265
Early research (Phase 1)Study completedNCT03586661
What this trial is testing

Niraparib and Copanlisib in Treating Patients With Recurrent Endometrial, Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

Who this might be right for
Deleterious BRCA1 Gene MutationDeleterious BRCA2 Gene MutationEndometrial Adenocarcinoma+8 more
M.D. Anderson Cancer Center 31
Early research (Phase 1)Study completedNCT03329001
What this trial is testing

Crossover Study to Assess the Relative Bioavailability and Bioequivalence of Niraparib Tablet Compared to Niraparib Capsule

Who this might be right for
Neoplasms
Tesaro, Inc. 236
Testing effectiveness (Phase 2)Active Not RecruitingNCT04701307
What this trial is testing

Niraparib and Dostarlimab for the Treatment of Small Cell Lung Cancer and Other High-Grade Neuroendocrine Carcinomas

Who this might be right for
Lung Small Cell CarcinomaNeuroendocrine CarcinomaStage III Lung Cancer AJCC v8+3 more
M.D. Anderson Cancer Center 48
Testing effectiveness (Phase 2)UnknownNCT04395612
What this trial is testing

Niraparib Combined With Brivanib or Toripalimab in Patients With Cervical Cancer

Who this might be right for
Cervical Cancer
Chongqing University Cancer Hospital 38
Not applicableStudy completedNCT04589039
What this trial is testing

Post-Marketing Surveillance of Niraparib in the Treatment of Adult Participants for Approved Indications in South Korea

Who this might be right for
Ovarian Neoplasms
Takeda 662
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