Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Non-Langerhans-Cell Histiocytosis”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 0 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT03155620
What this trial is testing

Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmAnn Arbor Stage III Non-Hodgkin LymphomaAnn Arbor Stage IV Non-Hodgkin Lymphoma+42 more
National Cancer Institute (NCI) 1,377
Not applicableUnknownNCT06587191
What this trial is testing

Emapalumab Efficacy in Children With Primary Hemophagocytic Lymphohistiocytosis

Who this might be right for
Primary Hemophagocytic Lymphohistiocytosis
Federal Research Institute of Pediatric Hematology, Oncology and Immunology 7
Testing effectiveness (Phase 2)Active Not RecruitingNCT03213652
What this trial is testing

Ensartinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With ALK or ROS1 Genomic Alterations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmMalignant Solid NeoplasmRecurrent Ependymoma+30 more
National Cancer Institute (NCI) 13
Not applicableLooking for participantsNCT06192576
What this trial is testing

A Real-world Long-term Safety and Immunogenicity Study of Olipudase Alfa Therapy in Pediatric Patients Less Than 2 Years of Age With Acid Sphingomyelinase Deficiency (ASMD)

Who this might be right for
Niemann-Pick DiseasesAcid Sphingomyelinase Deficiency
Sanofi 10
Large-scale testing (Phase 3)UnknownNCT06038422
What this trial is testing

GTP Regimen in the Treatment of Refractory/Recurrent HLH

Who this might be right for
RefractoryRecurrenceHemophagocytic Lymphohistiocytosis
Beijing Friendship Hospital 15
Early research (Phase 1)Active Not RecruitingNCT00710892
What this trial is testing

CASPALLO: Allodepleted T Cells Transduced With Inducible Caspase 9 Suicide Gene

Who this might be right for
Acute Lymphoblastic LeukemiaNon-Hodgkin's LymphomaMyelodysplastic Syndrome+1 more
Baylor College of Medicine 10
Testing effectiveness (Phase 2)Active Not RecruitingNCT02523040
What this trial is testing

Lenalidomide for Adult Histiocyte Disorders

Who this might be right for
Langerhans Cell Histiocytosis (LCH)Histiocytoses Erdheim-chester DiseaseHistiocytic Sarcoma (HS)
Dana-Farber Cancer Institute 12
Testing effectiveness (Phase 2)Study completedNCT02385110
What this trial is testing

Alemtuzumab or Tocilizumab in Combination With Etoposide and Dexamethasone for the Treatment of Adult Patients With Hemophagocytic Lymphohistiocytosis

Who this might be right for
Leukemia
M.D. Anderson Cancer Center 18
Not applicableLooking for participantsNCT05992532
What this trial is testing

GammaGA: Prevalence of Acid Sphingomyelinase Deficiency Disease (ASMD) and Gaucher Disease in Patients With Monoclonal Gammopathies and/or Multiple Myeloma

Who this might be right for
Gaucher DiseaseAcid SphingoMyelinase Deficiency
Fundación Española de Hematología y Hemoterapía 210
Testing effectiveness (Phase 2)Study completedNCT03471143
What this trial is testing

Study of IV VTS-270 for Infantile Liver Disease Associated With Niemann-Pick Disease, Type C

Who this might be right for
Niemann-Pick Disease, Type C
Washington University School of Medicine 4
Testing effectiveness (Phase 2)UnknownNCT03795909
What this trial is testing

Ruxolitinib Combined With Dexamethasone for HLH

Who this might be right for
Hemophagocytic Lymphohistiocytosis
Capital Research Institute of Pediatrics 50
Testing effectiveness (Phase 2)Ended earlyNCT01727206
What this trial is testing

Pilot Study of Tocilizumab in Patients With Erdheim-Chester Disease

Who this might be right for
Erdheim-Chester Disease
Ospedale San Raffaele 3
Large-scale testing (Phase 3)Looking for participantsNCT07054515
What this trial is testing

Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease, GM1 Gangliosidosis or GM2 Gangliosidosis

Who this might be right for
Niemann-Pick Type C DiseaseGM1 GangliosidosisGM2 Gangliosidosis
Azafaros B.V. 147
Not applicableLooking for participantsNCT06339177
What this trial is testing

Hemophagocytic Lymphohistiocytosis (HLH) Evaluation and Research of Clinical, ImmUnoLogic and TranscriptomE Study

Who this might be right for
Lymphohistiocytosis, HemophagocyticSecondary Hemophagocytic LymphohistiocytosisMacrophage Activation Syndrome+1 more
National Institute of Allergy and Infectious Diseases (NIAID) 300
Not applicableLooking for participantsNCT03329274
What this trial is testing

Registry for Patients With Erdheim-Chester Disease and Other Histiocytoses

Who this might be right for
Erdheim-Chester Disease
Memorial Sloan Kettering Cancer Center 500
Not applicableNot Yet RecruitingNCT06869499
What this trial is testing

Study of the Prevalence of Acid Sphingomyelinase Deficiency/Niemann Pick AB and B Disease in Patients With Diffuse Interstitial Lung Disease

Who this might be right for
SplenomegalySplenectomyThrombopenia+2 more
Wladimir MAUHIN, Dr 200
Testing effectiveness (Phase 2)Study completedNCT06949358
What this trial is testing

Evaluate Safety and Tolerability of Olipudase Alfa in Pediatric and Adult Participants With Acid Sphingomyelinase Deficiency (ASMD) Who Completed the DFI12712 or the LTS13632 Study in France

Who this might be right for
Acid Sphingomyelinase Deficiency
Sanofi 3
Not applicableWithdrawnNCT04189601
What this trial is testing

Complement Activation in the Lysosomal Storage Disorders

Who this might be right for
Fabry DiseaseGaucher DiseaseNiemann-Pick Disease, Type C+1 more
Melbourne Health
Testing effectiveness (Phase 2)Study completedNCT02912793
What this trial is testing

Safety and Efficacy of Intravenous Trappsol Cyclo (HPBCD) in Niemann-Pick Type C Patients

Who this might be right for
Niemann-Pick Disease, Type C1
Cyclo Therapeutics, Inc. 12
Testing effectiveness (Phase 2)Study completedNCT02472054
What this trial is testing

Treatment of Familiar Lymphohistiocytosis

Who this might be right for
Hemophagocytic Lymphohistiocytosis (HLH)
Assistance Publique - Hôpitaux de Paris 29
Next Page