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Results for “Non-clinical Participants”

168 trials

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Showing 20 of 168 results

Large-scale testing (Phase 3)Study completedNCT03293485
What this trial is testing

Efficacy and Safety of Imipenem+Cilastatin/Relebactam (MK-7655A) in Japanese Participants With Complicated Intra-abdominal Infection or Complicated Urinary Tract Infection (MK-7655A-017)

Who this might be right for
Complicated Intra-abdominal InfectionComplicated Urinary Tract Infection
Merck Sharp & Dohme LLC 83
Testing effectiveness (Phase 2)Looking for participantsNCT06892548
What this trial is testing

A Clinical Study to Investigate the Efficacy and Safety of an Investigational Combination Therapy With BNT324 and BNT327 in Patients With Advanced Lung Cancer

Who this might be right for
Advanced Lung Cancer
BioNTech SE 594
Early research (Phase 1)Looking for participantsNCT06665646
What this trial is testing

Clinical Trial to Evaluate the Safety and Immunogenicity of Hiltonol, Poly-ICLC-adjuvanted CD40.HIVRI.Env (VRIPRO) in Adult Participants Who Previously Participated in HVTN 706

Who this might be right for
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID) 40
Early research (Phase 1)Looking for participantsNCT06253520
What this trial is testing

Autologous T-cells Genetically Engineered to Express Receptors Reactive Against KRAS Mutations in Conjunction With a Vaccine Directed Against These Antigens in Participants With Metastatic Cancer

Who this might be right for
Metastatic Solid CancersColorectal CancerBreast Cancer+4 more
National Cancer Institute (NCI) 210
Not applicableActive Not RecruitingNCT05954910
What this trial is testing

Evaluate the Effectiveness and Safety of Polatuzumab in Real World Clinical Practice Among Adult Chinese Participants With Diffuse Large B-Cell Lymphoma

Who this might be right for
Diffuse Large B-Cell Lymphoma
Hoffmann-La Roche 1,000
Testing effectiveness (Phase 2)Study completedNCT02629822
What this trial is testing

Safety and Efficacy of Doravirine, Tenofovir, Lamivudine (MK-1439A) in Participants Infected With Treatment-Naïve Human Immunodeficiency Virus (HIV) -1 With Transmitted Resistance (MK-1439A-030)

Who this might be right for
HIV-1 Infection
Merck Sharp & Dohme LLC 10
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07249905
What this trial is testing

This Study is Designed to Characterize the Safety, Tolerability, and Anti-tumor Activity of MDX2003 in Patients With Different Types of Lymphoma

Who this might be right for
LymphomaWaldenström Macroglobulinemia (WM)DLBCL - Diffuse Large B Cell Lymphoma+5 more
ModeX Therapeutics, An OPKO Health Company 180
Testing effectiveness (Phase 2)Looking for participantsNCT06833073
What this trial is testing

A Clinical Study of Intismeran Autogene (V940) and BCG in People With Bladder Cancer (V940-011/INTerpath-011)

Who this might be right for
Urinary Bladder NeoplasmsNon-Muscle Invasive Bladder NeoplasmsCarcinoma in Situ
Merck Sharp & Dohme LLC 308
Early research (Phase 1)Ended earlyNCT01353898
What this trial is testing

Study of MK-1972 in Human Immunodeficiency Virus (HIV)-1 Infected Participants Who Have Not Previously Received Antiretroviral Therapy (MK-1972-003)

Who this might be right for
HIV-1 Infection
Merck Sharp & Dohme LLC 12
Large-scale testing (Phase 3)Active Not RecruitingNCT05722015
What this trial is testing

Subcutaneous (SC) Pembrolizumab Coformulated With Berahyaluronidase Alfa (MK-3475A) vs Intravenous Pembrolizumab in Adult Participants With Metastatic Non-small Cell Lung Cancer (NSCLC) (MK-3475A-D77)

Who this might be right for
Metastatic Non-small Cell Lung Cancer
Merck Sharp & Dohme LLC 377
Testing effectiveness (Phase 2)Study completedNCT03379675
What this trial is testing

Explore the Antiviral Activity, Clinical Outcomes, Safety, Tolerability, and Pharmacokinetics of JNJ-53718678 at Two Dose Levels in Non-Hospitalized Adult Participants Infected With Respiratory Syncytial Virus

Who this might be right for
Respiratory Syncytial Virus Infections
Janssen Research & Development, LLC 72
Not applicableStudy completedNCT02508090
What this trial is testing

Long-Term Extension Study of Miravirsen Among Participants With Genotype 1 Chronic Hepatitis C (CHC) Who Have Not Responded to Pegylated-Interferon Alpha Plus Ribavirin

Who this might be right for
Chronic Hepatitis C
Hoffmann-La Roche 10
Not applicableStudy completedNCT02234960
What this trial is testing

Local, Non-Interventional Study of RoActemra (Tocilizumab) in Poland (ACT-POL): First-Line Treatment in Routine Clinical Practice of Participants With Rheumatoid Arthritis (RA)

Who this might be right for
Rheumatoid Arthritis
Hoffmann-La Roche 102
Testing effectiveness (Phase 2)Looking for participantsNCT06914128
What this trial is testing

A First-in-human Study to Learn How Safe BAY 3713372 is and How it Works in Participants With MTAP-deleted Solid Tumors

Who this might be right for
MTAP-deleted Solid Tumors
Bayer 370
Not applicableActive Not RecruitingNCT05841537
What this trial is testing

An Observational Study to Assess Change in Disease Activity and Adverse Events In Adult Participants With Moderate to Severe Active Crohn's Disease (CD)

Who this might be right for
Crohn's Disease
AbbVie 1,019
Testing effectiveness (Phase 2)UnknownNCT04370405
What this trial is testing

YY-20394 in Participants With Relapsed/Refractory Follicular Non-Hodgkin's Lymphoma

Who this might be right for
Lymphoma, Follicular
Shanghai YingLi Pharmaceutical Co. Ltd. 123
Early research (Phase 1)Study completedNCT04317066
What this trial is testing

Pembrolizumab (MK-3475) in Participants With Relapsed or Refractory Primary Mediastinal Large B-cell Lymphoma (rrPMBCL) (MK-3475-A33/KEYNOTE-A33)

Who this might be right for
Lymphoma, B-Cell
Merck Sharp & Dohme LLC 7
Post-approval studies (Phase 4)Active Not RecruitingNCT06372496
What this trial is testing

Pragmatic Open - Label Randomized Clinical Trial of FF/UMEC/VI vs Non-ellipta Usual Care ICS-LABA for Adult Participants With Uncontrolled Asthma

Who this might be right for
Asthma
GlaxoSmithKline 1,357
Early research (Phase 1)Looking for participantsNCT03666000
What this trial is testing

Dose-escalation and Dose-expansion Study of Safety of Azer-cel (PBCAR0191) in Participants With Relapsed/Refractory (r/r) Non-Hodgkin Lymphoma (NHL) and r/r B-cell Acute Lymphoblastic Leukemia (B-ALL)

Who this might be right for
Non-Hodgkin LymphomaB-cell Acute Lymphoblastic LeukemiaChronic Lymphocytic Leukemia+1 more
Imugene Limited 135
Large-scale testing (Phase 3)Active Not RecruitingNCT03711032
What this trial is testing

Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Bacillus Calmette-Guerin (BCG) in High-Risk Non-Muscle Invasive Bladder Cancer (HR NMIBC) (MK-3475-676/KEYNOTE-676)

Who this might be right for
High-risk Non-muscle Invasive Bladder Cancer
Merck Sharp & Dohme LLC 1,397
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