Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Non-small Cell Lung Cancer (NSCLC) With Brain Metastases”

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 0 results

Testing effectiveness (Phase 2)Active Not RecruitingNCT05256290
What this trial is testing

Phase 1/2 Study of Silevertinib (BDTX-1535) in Patients With Glioblastoma or Non-Small Cell Lung Cancer With EGFR Mutations

Who this might be right for
Non-Small Cell Lung CancerAdvanced Non-Small Cell Squamous Lung CancerMetastatic Lung Non-Small Cell Carcinoma+7 more
Black Diamond Therapeutics, Inc. 200
Not applicableUnknownNCT05737589
What this trial is testing

Circulating Tumor DNA and T Cell Repertoire Predict Radiotherapeutic Outcomes in NSCLC Patients With Brain Metastasis

Who this might be right for
Carcinoma, Non-Small-Cell LungBrain Metastases
Xiaorong Dong 50
Testing effectiveness (Phase 2)Looking for participantsNCT07206498
What this trial is testing

Evaluate Safety and Efficacy of WSD0922-FU Combo With Osimertinib for NSCLC

Who this might be right for
Non Small Cell Lung Cancer (NSCLC)
Wayshine Biopharm, Inc. 48
Testing effectiveness (Phase 2)Ended earlyNCT01518621
What this trial is testing

Whole Brain Radiation With or Without Erlotinib for Brain Metastases From Non-Small Cell Lung Cancer

Who this might be right for
Cancer
Oslo University Hospital 25
Not applicableUnknownNCT04787185
What this trial is testing

Stereotactic Radiotherapy in Association With Immunotherapy for the Treatment of NSCLC Brain Metastases

Who this might be right for
Brain Metastases From NSCLC
Azienda Ospedaliero-Universitaria Careggi 50
Testing effectiveness (Phase 2)Study completedNCT03520842
What this trial is testing

Regorafenib and Methotrexate in Treating Participants With Recurrent or Metastatic KRAS Mutated Non-Small Cell Lung Cancer

Who this might be right for
KRAS Gene MutationMetastatic Malignant Neoplasm in the BrainRecurrent Non-Small Cell Lung Carcinoma+1 more
Stanford University 22
Large-scale testing (Phase 3)Study completedNCT05807893
What this trial is testing

Study to Evaluate the Safety and Efficacy of Serplulimab Plus Bevacizumab and Chemotherapy in NSCLC Patients With Brain Metastases

Who this might be right for
Non-small Cell Lung Cancer Stage IIBevacizumabImmunotherapy+1 more
Sun Yat-sen University 40
Early research (Phase 1)Looking for participantsNCT07361562
What this trial is testing

A Selective ERBB2 Inhibitor (CGT4255), in Patients With Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor, AdultERBB2 Altered Breast CancerERBB2 Gene Amplification+3 more
Cogent Biosciences, Inc. 100
Large-scale testing (Phase 3)UnknownNCT02714010
What this trial is testing

EGFR-TKI Concurrent With/Without WBRT in Brain Metastasis From NSCLC

Who this might be right for
Non-Small Cell Lung Cancer
Sun Yat-sen University 601
Not applicableActive Not RecruitingNCT05703269
What this trial is testing

Comparing Single vs Multiple Dose Radiation for Cancer Patients With Brain Metastasis and Receiving Immunotherapy

Who this might be right for
NSCLCRenal Cell CarcinomaBreast Carcinoma+5 more
Wake Forest University Health Sciences 58
Early research (Phase 1)UnknownNCT03638765
What this trial is testing

Dendritic Cell Therapy for Brain Metastases From Breast- or Lung Cancer

Who this might be right for
Brain MetastasesLung Cancer MetastaticBreast Cancer Metastatic
Northwest Biotherapeutics 24
Testing effectiveness (Phase 2)Looking for participantsNCT06401824
What this trial is testing

Sacituzumab Govitecan and Bevacizumab for NSCLC Brain Metastases

Who this might be right for
NSCLC Stage IVBrain Metastases, Adult
Maastricht University Medical Center 25
Testing effectiveness (Phase 2)Ended earlyNCT00280748
What this trial is testing

Whole-Brain Radiation Therapy and Pemetrexed in Treating Patients With Brain Metastases From Non-Small Cell Lung Cancer

Who this might be right for
Lung CancerMetastatic Cancer
UNC Lineberger Comprehensive Cancer Center 10
Large-scale testing (Phase 3)Active Not RecruitingNCT06500455
What this trial is testing

Testing Longer Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With Cancer That Has Spread to the Brain

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8Metastatic Breast CarcinomaMetastatic Digestive System Carcinoma+7 more
NRG Oncology 274
Testing effectiveness (Phase 2)Looking for participantsNCT05692635
What this trial is testing

Reducing the Incidence of Symptomatic Brain Metastases With MRI Surveillance

Who this might be right for
Brain MetastasesNonsmall Cell Lung Cancer Stage III
Wake Forest University Health Sciences 60
Testing effectiveness (Phase 2)Ended earlyNCT00554775
What this trial is testing

WBRT & Erlotinib in Advanced NSCLC and Brain Metastases

Who this might be right for
Lung CancerMetastatic Cancer
University College, London 80
Large-scale testing (Phase 3)UnknownNCT00955695
What this trial is testing

Radiation Therapy to the Brain or Observation in Preventing Brain Metastases in Patients With Advanced Non-Small Cell Lung Cancer

Who this might be right for
Lung Cancer
National Cancer Center, Korea 242
Testing effectiveness (Phase 2)Study completedNCT00800202
What this trial is testing

Avastin (Bevacizumab) in Patients With Non-Squamous Non-Small Cell Lung Cancer With Asymptomatic Untreated Brain Metastasis

Who this might be right for
Non-Small Cell Lung Cancer
Hoffmann-La Roche 91
Large-scale testing (Phase 3)Study completedNCT00538850
What this trial is testing

Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain

Who this might be right for
Cancer
INSYS Therapeutics Inc 130
Testing effectiveness (Phase 2)Ended earlyNCT04789668
What this trial is testing

Bintrafusp Alfa and Pimasertib for the Treatment of Patients With Brain Metastases

Who this might be right for
Anatomic Stage IV Breast Cancer AJCC v8Clinical Stage IV Cutaneous Melanoma AJCC v8Hematopoietic and Lymphoid Cell Neoplasm+11 more
M.D. Anderson Cancer Center 8
Next Page