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Results for “Non-small Cell Lung Cancer With STK11/LKB1 Mutation”

9 trials

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Showing 9 of 9 results

Testing effectiveness (Phase 2)Ended earlyNCT05469178
What this trial is testing

A Clinical Study of Bemcentinib With Standard of Care Chemoimmunotherapy in Untreated Advanced/Metastatic Non-small Cell Lung Cancer Patients With a Mutation in the STK11 Gene

Who this might be right for
Carcinoma, Non-Small-Cell Lung
BerGenBio ASA 26
Testing effectiveness (Phase 2)Study completedNCT05807048
What this trial is testing

Daratumumab in STK11 Mutated NSCLC

Who this might be right for
Non-small Cell Lung Cancer With STK11/LKB1 Mutation
NYU Langone Health 8
Testing effectiveness (Phase 2)Ended earlyNCT04265534
What this trial is testing

KEAPSAKE: A Study of Telaglenastat (CB-839) With Standard-of-Care Chemoimmunotherapy in 1L KEAP1/NRF2-Mutated, Nonsquamous NSCLC

Who this might be right for
Non-Small Cell Lung CancerNon-squamous Non-small-cell Lung CancerNon-Squamous Non-Small Cell Neoplasm of Lung+3 more
Calithera Biosciences, Inc 40
Not applicableEnded earlyNCT04698681
What this trial is testing

NGS Screening Protocol to Detect Mutation of KEAP1 or NRF2/NFE2L2 Genes for the KEAPSAKE (CX-839-014) Trial

Who this might be right for
Non-Small Cell Lung CancerNon-squamous Non-small-cell Lung CancerNon-Squamous Non-Small Cell Neoplasm of Lung+3 more
Calithera Biosciences, Inc 20
Testing effectiveness (Phase 2)Study completedNCT05054725
What this trial is testing

Combination Study of RMC-4630 and Sotorasib for NSCLC Subjects With KRASG12C Mutation After Failure of Prior Standard Therapies

Who this might be right for
Non-Small Cell Lung Cancer
Revolution Medicines, Inc. 47
Early research (Phase 1)Active Not RecruitingNCT05462717
What this trial is testing

Dose Escalation and Dose Expansion Study of RMC-6291 Monotherapy in Subjects With Advanced KRASG12C Mutant Solid Tumors

Who this might be right for
Non-Small Cell Lung Cancer (NSCLC)Colorectal Cancer (CRC)Pancreatic Ductal Adenocarcinoma+1 more
Revolution Medicines, Inc. 222
Testing effectiveness (Phase 2)Looking for participantsNCT05887492
What this trial is testing

Study of TNG260 and an Anti-PD Antibody in STK11 Mutated Solid Tumors

Who this might be right for
Non Small Cell Lung CancerSolid Tumors, AdultLung Cancer+1 more
Tango Therapeutics, Inc. 126
Testing effectiveness (Phase 2)Looking for participantsNCT06128551
What this trial is testing

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

Who this might be right for
Non-Small Cell Lung Cancer (NSCLC)Colorectal CancerPancreatic Ductal Adenocarcinoma
Revolution Medicines, Inc. 534
Testing effectiveness (Phase 2)Study completedNCT04173507
What this trial is testing

Combination Treatment (Talazoparib Plus Avelumab) for Stage IV or Recurrent Non-Squamous Non-Small Cell Lung Cancer With STK11 Gene Mutation (A LUNG-MAP Treatment Trial)

Who this might be right for
Advanced Lung Non-Squamous Non-Small Cell CarcinomaRecurrent Lung Non-Squamous Non-Small Cell CarcinomaStage IV Lung Cancer AJCC v8+2 more
SWOG Cancer Research Network 47