Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Obstructive Hypertrophic Cardiomyopathy (oHCM)”

30 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 30 results

Not applicableLooking for participantsNCT06023186
What this trial is testing

Effect of Mavacamten Treatment on Coronary Flow Reserve in oHCM

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy
Michael Ayers 20
Not applicableStudy completedNCT06609382
What this trial is testing

Left Ventricular Mass Index Predicts Clinical Outcomes in Patients with Obstructive Hypertrophic Cardiomyopathy Undergoing Septal Myectomy

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy (oHCM)
Changrong Nie 490
Not applicableNot Yet RecruitingNCT07439952
What this trial is testing

Biological Collection for the Purpose of Exploring Genetic and Clinical-biological Factors Associated With Variability in Response to Mavacamten in the Treatment of Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy (oHCM)
Assistance Publique - Hôpitaux de Paris 300
Not applicableLooking for participantsNCT07383025
What this trial is testing

Mavacamten Post-marketing Surveillance in Patients With Obstructive Hypertrophic Cardiomyopathy in Japan

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy (oHCM)
Bristol-Myers Squibb 200
Post-approval studies (Phase 4)Active Not RecruitingNCT06112743
What this trial is testing

Evaluate Mavacamten Impact on Myocardial Structure in Participants With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Cardiomyopathy, Hypertrophic
Bristol-Myers Squibb 63
Not applicableStudy completedNCT06338202
What this trial is testing

Real-World Effectiveness of Mavacamten in Canada

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy (oHCM)
Bristol-Myers Squibb 115
Not applicableActive Not RecruitingNCT07695272
What this trial is testing

Radiomics Analysis of CMR Imaging for Arrhythmic Risk Prediction in Hypertrophic Cardiomyopathy, With Longitudinal Risk Reassessment After Mavacamten Therapy in Obstructive Patients

Who this might be right for
Hypertrophic Cardiomyopathy (HCM)Cardiac Myosin Inhibitors
Centro Cardiologico Monzino 2,000
Not applicableActive Not RecruitingNCT07107373
What this trial is testing

Assess the Treatment of Obstructive Hypertrophic Cardiomyopathy (oHCM) With Mavacamten in the US

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy (oHCM)
Bristol-Myers Squibb 150
Large-scale testing (Phase 3)Study completedNCT06116968
What this trial is testing

An Open-Label Study of Aficamten for Chinese Patients With Symptomatic oHCM

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy
Corxel Pharmaceuticals 40
Early research (Phase 1)Study completedNCT03767855
What this trial is testing

A Single and Multiple Ascending Dose Study of CK-3773274 in Healthy Adult Subjects

Who this might be right for
Symptomatic Obstructive Hypertrophic CardiomyopathyHealthy Subjects
Cytokinetics 114
Not applicableLooking for participantsNCT06146660
What this trial is testing

Assess the Safety of Mavacamten in Korean Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy
Bristol-Myers Squibb 600
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07675668
What this trial is testing

Aom0304 in Adult Patients With Symptomatic Hypertrophic Cardiomyopathy

Who this might be right for
Hypertrophic Cardiomyopathy (HCM)Obstructive HCM (oHCM)Non-obstructive HCM (nHCM)
Amckaus PTY LTD. 56
Large-scale testing (Phase 3)Study completedNCT05767346
What this trial is testing

Phase 3 Trial to Evaluate the Efficacy and Safety of Aficamten Compared to Metoprolol Succinate in Adults With Symptomatic oHCM

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy (oHCM)
Cytokinetics 175
Large-scale testing (Phase 3)Enrolling By InvitationNCT04848506
What this trial is testing

Open-label Extension Study to Evaluate the Long-term Safety and Tolerability of Aficamten in Adults With HCM

Who this might be right for
Symptomatic Hypertrophic Cardiomyopathy (HCM)
Cytokinetics 900
Testing effectiveness (Phase 2)Study completedNCT04219826
What this trial is testing

Dose-finding Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of CK-3773274 in Adults With Hypertrophic Cardiomyopathy

Who this might be right for
Hypertrophic Cardiomyopathy (HCM)
Cytokinetics 96
Large-scale testing (Phase 3)Active Not RecruitingNCT06253221
What this trial is testing

Evaluate Mavacamten in Adolescents With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Cardiomyopathy, Hypertrophic
Bristol-Myers Squibb 44
Not applicableLooking for participantsNCT07557498
What this trial is testing

Mavacamten Outcomes in Hypertrophic Cardiomyopathy (HCM) and the Associated Patient and Physician Experiences in the US

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy (oHCM)
Bristol-Myers Squibb 362
Not applicableStudy completedNCT07168655
What this trial is testing

Mavacamten in Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Obstructive Hypertrophic Cardiomyopathy (oHCM)
Bristol-Myers Squibb 163
Early research (Phase 1)Study completedNCT04783766
What this trial is testing

Safety, Tolerability and Pharmacokinetics Study of CK-3773274

Who this might be right for
Obstructive Hypertrophic CardiomyopathyHealthy Adult Subjects
Corxel Pharmaceuticals 28
Large-scale testing (Phase 3)Not Yet RecruitingNCT07755904
What this trial is testing

BHB-1893 Versus Metoprolol for Symptomatic Obstructive Hypertrophic Cardiomyopathy

Who this might be right for
Cardiomyopathy, Hypertrophic Obstructive
Braveheart Bio, Inc. 210
Next Page