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Results for “Opioid Antagonist”

55 trials

Showing 20 of 55 results

Testing effectiveness (Phase 2)WithdrawnNCT04325802
What this trial is testing

Treatment of Chronic Itch in Atopic Dermatitis With Opioid Antagonist Naltrexone

Who this might be right for
Atopic DermatitisPruritusPruritus Chronic+1 more
University of Minnesota
Testing effectiveness (Phase 2)Study completedNCT00460239
What this trial is testing

Buprenorphine's Dose Response Curve

Who this might be right for
Opioid-related Disorders
Johns Hopkins University 12
Testing effectiveness (Phase 2)Study completedNCT05546515
What this trial is testing

Suvorexant for Opioid/Stimulant Co-use

Who this might be right for
Opioid Use DisorderStimulant Use Disorder
Johns Hopkins University 20
Early research (Phase 1)Study completedNCT02133820
What this trial is testing

Assess How the Body Processes a Strong Painkiller When it is Given Alongside a Drug That Counteracts the Side Effects of Strong Painkillers in a Fasted and Fed State.

Who this might be right for
Pain
Mundipharma Research Limited 16
Post-approval studies (Phase 4)Study completedNCT01673594
What this trial is testing

Prevention of Stimulant-Induced Euphoria With an Opioid Receptor Antagonist

Who this might be right for
ADHDStimulant-Induced Euphoria
Massachusetts General Hospital 37
Large-scale testing (Phase 3)Study completedNCT03518021
What this trial is testing

Naloxone Nasal Spray Compared With Naloxone Injection for Opioid Overdoses Outside the Hospital

Who this might be right for
OverdoseDrug Abuse
Norwegian University of Science and Technology 286
Not applicableStudy completedNCT01531439
What this trial is testing

Comparison of Two Naloxone Infusion Rates on the Postoperative Recovery of Patients Undergoing Spine Fusion Surgery

Who this might be right for
Pain, PostoperativePostoperative Nausea and VomitingScoliosis
Children's Mercy Hospital Kansas City 84
Early research (Phase 1)Ended earlyNCT01431586
What this trial is testing

First in Humans Study of JDTic

Who this might be right for
Cocaine Dependence
RTI International 24
Testing effectiveness (Phase 2)Ended earlyNCT00142727
What this trial is testing

Opioid Agonist and Antagonist Effects on Opioid Dependence

Who this might be right for
Opioid-Related Disorders
National Institute on Drug Abuse (NIDA) 16
Early research (Phase 1)Study completedNCT01889290
What this trial is testing

Methylnaltrexone Pharmacokinetics in Neurointensive Care Patients

Who this might be right for
Opioid Use, Unspecified With Other Opioid-induced Disorder
University of Zurich 9
Testing effectiveness (Phase 2)Study completedNCT02322047
What this trial is testing

Prazosin and Naltrexone (PaN) Study for Veterans With Alcohol Use Disorders

Who this might be right for
Alcohol Use DisorderPosttraumatic Stress Disorder (PTSD)
Seattle Institute for Biomedical and Clinical Research 31
Testing effectiveness (Phase 2)Ended earlyNCT04355169
What this trial is testing

Naldemedine in Participants Undergoing Surgeries That Include a Bowel Resection or Bowel Transection

Who this might be right for
Postoperative Gastrointestinal Dysfunction
Shionogi 2
Testing effectiveness (Phase 2)Study completedNCT01207427
What this trial is testing

Evaluation of the Efficacy and Safety of ADL5945 for the Treatment of Opioid-induced Constipation in Adults Taking Opioid Therapy for Chronic Noncancer Pain

Who this might be right for
Opioid Induced Constipation
Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) 131
Large-scale testing (Phase 3)Ended earlyNCT00269607
What this trial is testing

Naltrexone Implants as Relapse Prevention

Who this might be right for
Opioid Dependency
University of Oslo 12
Not applicableActive Not RecruitingNCT03337009
What this trial is testing

The Impact of a Web-Based Naloxone Intervention Under Standing Orders to Patients Prescribed Chronic Opioid Therapy

Who this might be right for
OverdoseRisk Behavior
Kaiser Permanente 1,004
Early research (Phase 1)Study completedNCT00800319
What this trial is testing

ALK33-001: A Study of RDC-0313 Administered to Healthy Adults

Who this might be right for
Alcohol Dependence
Alkermes, Inc. 16
Large-scale testing (Phase 3)Study completedNCT04743570
What this trial is testing

Effects of Peripherally Acting µ-opioid Receptor Antagonists on Acute Pancreatitis

Who this might be right for
Acute Pancreatitis
Asbjørn Mohr Drewes 105
Not applicableStudy completedNCT00999544
What this trial is testing

Aprepitant Effects on Oxycodone Response

Who this might be right for
Narcotic Abuse
Sharon Walsh 9
Testing effectiveness (Phase 2)Ended earlyNCT03087708
What this trial is testing

Naloxegol in Treating Patients With Stage IIIB-IV Non-small Cell Lung Cancer

Who this might be right for
Stage IIIB Non-Small Cell Lung CancerStage IV Non-small Cell Lung Cancer
Alliance for Clinical Trials in Oncology 50
Testing effectiveness (Phase 2)Study completedNCT04052139
What this trial is testing

St. PETERsburg Pain and Alcohol Intervention With Naltrexone and Gabapentin

Who this might be right for
Chronic PainAlcohol Use, UnspecifiedHIV Infections
Boston Medical Center 45
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