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Results for “Opioid Antagonist”

58 trials

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Showing 20 of 58 results

Early research (Phase 1)Study completedNCT04764630
What this trial is testing

Clinical Study to Investigate the Pharmacokinetics of Multiple Repeated Doses of Intranasal Naloxone

Who this might be right for
Healthy SubjectsOpioid AntagonistPharmacokinetics
Food and Drug Administration (FDA) 21
Not applicableStudy completedNCT02362256
What this trial is testing

The Comparison of Stress Response to Rapid Opioid Detoxification Applying Different Methods of Opioid Antagonism

Who this might be right for
Opiate Addiction
Vilnius University 60
Not applicableUnknownNCT01553435
What this trial is testing

Effect of N-methyl D-aspartate (NMDA) Receptor Antagonist Dextromethorphan on Opiods Analgesia and Tolerance in Pediatric Intensive Care Unit Patients

Who this might be right for
PainOpioid ToleranceAnalgesia Tolerance
King Abdullah International Medical Research Center 36
Large-scale testing (Phase 3)Ended earlyNCT01601704
What this trial is testing

Cardiovascular Outcomes Study of Naltrexone SR/Bupropion SR in Overweight and Obese Subjects With Cardiovascular Risk Factors (The Light Study)

Who this might be right for
ObesityOverweight
Orexigen Therapeutics, Inc 8,910
Large-scale testing (Phase 3)Ended earlyNCT00124839
What this trial is testing

Naltrexone in Borderline Personality Disorder

Who this might be right for
Borderline Personality Disorder
Central Institute of Mental Health, Mannheim 48
Early research (Phase 1)Ended earlyNCT01431586
What this trial is testing

First in Humans Study of JDTic

Who this might be right for
Cocaine Dependence
RTI International 24
Testing effectiveness (Phase 2)UnknownNCT03430180
What this trial is testing

Effects of Intranasal Naloxone on Gambling Urges and Craving in Gambling Disorder

Who this might be right for
Pathological GamblingGambling DisorderOpioid Antagonist+1 more
Finnish Institute for Health and Welfare 126
Not applicableStudy completedNCT04015115
What this trial is testing

Youth Opioid Recovery Support: Improving Care Systems

Who this might be right for
Opioid-Related Disorders
University of Maryland, Baltimore 44
Not applicableStudy completedNCT02669901
What this trial is testing

Naloxone Auto-injector as a Universal Precaution for Patients With Opioid Use Disorder

Who this might be right for
Opiate Antagonist OverdoseOpioid-Related Disorders
University of New Mexico 395
Early research (Phase 1)Study completedNCT00800319
What this trial is testing

ALK33-001: A Study of RDC-0313 Administered to Healthy Adults

Who this might be right for
Alcohol Dependence
Alkermes, Inc. 16
Testing effectiveness (Phase 2)Ended earlyNCT01913535
What this trial is testing

Proof-of-Concept Trial of CERC-501 Augmentation of Antidepressant Therapy in Treatment-Resistant Depression

Who this might be right for
Treatment Resistant Depression
Massachusetts General Hospital 8
Early research (Phase 1)Ended earlyNCT00618397
What this trial is testing

Pharmacokinetics of Low Dose Ketamine Infusion

Who this might be right for
SedationOpioid Tolerance
University of Texas Southwestern Medical Center 5
Testing effectiveness (Phase 2)Study completedNCT03223896
What this trial is testing

Treatment of Gambling Disorder With Fast Acting Opiate Antagonist, Naloxone Nasal Spray

Who this might be right for
GamblingOpioidNaloxone+1 more
Finnish Institute for Health and Welfare 20
Large-scale testing (Phase 3)Ended earlyNCT00269607
What this trial is testing

Naltrexone Implants as Relapse Prevention

Who this might be right for
Opioid Dependency
University of Oslo 12
Testing effectiveness (Phase 2)Study completedNCT02322047
What this trial is testing

Prazosin and Naltrexone (PaN) Study for Veterans With Alcohol Use Disorders

Who this might be right for
Alcohol Use DisorderPosttraumatic Stress Disorder (PTSD)
Seattle Institute for Biomedical and Clinical Research 31
Post-approval studies (Phase 4)Study completedNCT02403830
What this trial is testing

Effect of Methylnaltrexone on the PK/PD Profiles of Ticagrelor in Patients Treated With Morphine

Who this might be right for
Coronary Artery Disease
University of Florida 30
Testing effectiveness (Phase 2)Study completedNCT01207427
What this trial is testing

Evaluation of the Efficacy and Safety of ADL5945 for the Treatment of Opioid-induced Constipation in Adults Taking Opioid Therapy for Chronic Noncancer Pain

Who this might be right for
Opioid Induced Constipation
Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) 131
Testing effectiveness (Phase 2)UnknownNCT04219046
What this trial is testing

Evaluation of Naloxegol in the Prevention of POI After Cystectomy

Who this might be right for
Bladder CancerCystostomy; Complications
Institut Paoli-Calmettes 102
Testing effectiveness (Phase 2)WithdrawnNCT04325802
What this trial is testing

Treatment of Chronic Itch in Atopic Dermatitis With Opioid Antagonist Naltrexone

Who this might be right for
Atopic DermatitisPruritusPruritus Chronic+1 more
University of Minnesota
Early research (Phase 1)Study completedNCT01367561
What this trial is testing

Naloxone and Intravenous Methylnaltrexone Effects on Bladder Function

Who this might be right for
Healthy Males
Bausch Health Americas, Inc. 15
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