Large-scale testing (Phase 3)UnknownNCT03316859What this trial is testingNaloxegol and Opioid-induced ConstipationWho this might be right forConstipationConstipation Drug Induced TriHealth Inc. 280
Testing effectiveness (Phase 2)Study completedNCT01367574What this trial is testingMethylnaltrexone in Patients With Opioid-Induced Bowel DysfunctionWho this might be right forBowel Dysfunction Bausch Health Americas, Inc. 39
Large-scale testing (Phase 3)Study completedNCT00401362What this trial is testingA a Single Dose Efficacy Study in Inducing Laxation in Advance Illness PatientsWho this might be right forAdvanced Illness Patients With Opioid Induced Constipation Bausch Health Americas, Inc. 154
Testing effectiveness (Phase 2)Study completedNCT01122030What this trial is testingStudy to Evaluate the Safety and Efficacy of Naldemedine (S-297995) for the Treatment of Opioid-Induced Bowel Dysfunction in Subjects With Chronic PainWho this might be right forOpioid Induced Bowel Dysfunction Shionogi 72
Not applicableStudy completedNCT01812733What this trial is testingNon-interventional Study Comparing Targiniq and Oxycodone/LaxativesWho this might be right forPainOpioid Induced Constipation Mundipharma AB 37
Large-scale testing (Phase 3)Study completedNCT00804141What this trial is testingStudy Evaluating Long-Term Safety of MOA-728 in Participants With Opioid-Induced ConstipationWho this might be right forConstipation Bausch Health Americas, Inc. 1,040
Not applicableStudy completedNCT04350112What this trial is testingStudy of Opioid-Induced Constipation 1 ProjectWho this might be right forOpioid-induced ConstipationCancerCancer Pain Royal Surrey County Hospital NHS Foundation Trust 1,007
Testing effectiveness (Phase 2)Study completedNCT01040637What this trial is testingA Multiple Dose Study of TD-1211 in Healthy Volunteers and Patients With Opioid-Induced ConstipationWho this might be right forHealthyOpioid-induced Constipation Theravance Biopharma 102
Post-approval studies (Phase 4)Study completedNCT00672139What this trial is testingSafety of Subcutaneous Methylnaltrexone for Opioid-Induced Constipation in Patients With Advanced IllnessWho this might be right forOpioid-Induced Constipation Bausch Health Americas, Inc. 156
Large-scale testing (Phase 3)Ended earlyNCT01901341What this trial is testingThe Efficacy and Safety Study of CB-5945 for the Treatment of Opioid-Induced ConstipationWho this might be right forOpioid-Induced Constipation Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) 44
Large-scale testing (Phase 3)Ended earlyNCT01384292What this trial is testingAssessment of Efficacy and Safety in Relieving Opioid-induced Constipation in Patients With Cancer-related PainWho this might be right forOpioid-Induced Constipation AstraZeneca 14
Testing effectiveness (Phase 2)Ended earlyNCT02745353What this trial is testingNaloxegol in Cancer Opioid-Induced ConstipationWho this might be right forConstipation Joseph Ma 7
Not applicableStudy completedNCT03355807What this trial is testingUse of MgSO4 for Pain After Bariatric SurgeryWho this might be right forTherapeutic Opioid Induced Constipation (Disorder) Yeditepe University Hospital 80
Testing effectiveness (Phase 2)Study completedNCT00101998What this trial is testingStudy Of Alvimopan Drug For Treatment Of Constipation Due To Prescription Pain MedicationWho this might be right forConstipationBowel Dysfunction Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) 233
Testing effectiveness (Phase 2)Study completedNCT02137213What this trial is testingFeasibility Study of Oral Naloxone for Treatment of Methadone-induced ConstipationWho this might be right forConstipation Centre for Addiction and Mental Health 20
Testing effectiveness (Phase 2)Study completedNCT00547586What this trial is testingStudy Evaluating Oral MOA-728 For The Treatment Of OIBD In Subjects With Chronic Non-Malignant PainWho this might be right forConstipation Bausch Health Americas, Inc. 122
Post-approval studies (Phase 4)Ended earlyNCT02839889What this trial is testingTolerability, Safety, and Feasibility of Naloxegol in Patients With Cancer and OIC (Opioid Induced Constipation)Who this might be right forCancerConstipationPain Hospice of Henderson County, Inc. 12
Large-scale testing (Phase 3)Study completedNCT01965652What this trial is testingLong Term Safety of NaldemedineWho this might be right forOpioid-induced Constipation Shionogi 1,246
Post-approval studies (Phase 4)Study completedNCT02573922What this trial is testingOpioid Induced Bowel Dysfunction in Patients Undergoing Spinal SurgeryWho this might be right forConstipation Kuopio University Hospital 180
Testing effectiveness (Phase 2)Study completedNCT01983306What this trial is testingDose-ranging Study to Assess Safety and Efficacy of SP-333 for the Treatment of Opioid-induced Constipation (OIC)Who this might be right forConstipation Bausch Health Americas, Inc. 292