Not applicableEnded earlyNCT01955213What this trial is testingMethylnaltrexone for Opioid Induced ConstipationWho this might be right forConstipation Amsterdam UMC, location VUmc 7
Large-scale testing (Phase 3)Study completedNCT01993940What this trial is testingEfficacy and Safety of Naldemedine in Treating Opioid-induced ConstipationWho this might be right forOpioid-induced Constipation Shionogi 553
Large-scale testing (Phase 3)Ended earlyNCT01901341What this trial is testingThe Efficacy and Safety Study of CB-5945 for the Treatment of Opioid-Induced ConstipationWho this might be right forOpioid-Induced Constipation Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) 44
Large-scale testing (Phase 3)Study completedNCT01309841What this trial is testingAssessment of Efficacy and Safety in Patients With Non-cancer-related Pain and Opioid-induced ConstipationWho this might be right forOpioid-Induced Constipation (OIC) AstraZeneca 652
Post-approval studies (Phase 4)Looking for participantsNCT07038551What this trial is testingProphylactic Use of Naldemedine on Opioid-induced Nausea and Vomiting in Patients With Cancer: POSEIDON StudyWho this might be right forOpioid-Induced Constipation (OIC) International University of Health and Welfare 120
Large-scale testing (Phase 3)Study completedNCT00804141What this trial is testingStudy Evaluating Long-Term Safety of MOA-728 in Participants With Opioid-Induced ConstipationWho this might be right forConstipation Bausch Health Americas, Inc. 1,040
Testing effectiveness (Phase 2)Study completedNCT02270983What this trial is testingPhase 2 Randomized, Double-Blind, Placebo-Controlled, Parallel Group Trial of Linaclotide Administered to Patients With Opioid-Induced Constipation Receiving Chronic Opioid Treatment for Non-Cancer PainWho this might be right forOpioid-Induced Constipation Forest Laboratories 254
Testing effectiveness (Phase 2)Study completedNCT01367574What this trial is testingMethylnaltrexone in Patients With Opioid-Induced Bowel DysfunctionWho this might be right forBowel Dysfunction Bausch Health Americas, Inc. 39
Large-scale testing (Phase 3)Study completedNCT00936884What this trial is testingStudy Evaluating the Efficacy and Safety of Subcutaneous Methylnaltrexone (MOA-728) for the Treatment of Opioid-Induced-ConstipationWho this might be right forConstipation Bausch Health Americas, Inc. 50
Testing effectiveness (Phase 2)Study completedNCT00600119What this trial is testingA Phase 2, Double-Blind, Multiple-Dose Escalation Study to Evaluate NKTR-118 (Oral PEG-Naloxol) in Patients With Opioid-Induced Constipation (OIC)Who this might be right forOpioid Induced Constipation (OIC) AstraZeneca 207
Not applicableStudy completedNCT00662363What this trial is testingLubiprostone (Amitiza®) Vs. Standard Care in Opioid-induced Constipation After Surgery in Inpatient RehabilitationWho this might be right forConstipation Shirley Ryan AbilityLab 64
Testing effectiveness (Phase 2)Study completedNCT01004393What this trial is testingMethylnaltrexone for Opioid-induced Constipation in Cancer PatientsWho this might be right forNeoplasmsConstipationOpioid-Related Disorders University of Vermont 12
Early research (Phase 1)Study completedNCT01655771What this trial is testingTD-1211 Single-Dose Study in Elderly and Young Healthy SubjectsWho this might be right forConstipation Theravance Biopharma 47
Testing effectiveness (Phase 2)Study completedNCT05133076What this trial is testingSafety and Preliminary Efficacy of BGP345A in Constipation Due to Opioid-based MedicationsWho this might be right forOpioid-Induced Constipation BioGaia Pharma AB 14
Not applicableStudy completedNCT04350112What this trial is testingStudy of Opioid-Induced Constipation 1 ProjectWho this might be right forOpioid-induced ConstipationCancerCancer Pain Royal Surrey County Hospital NHS Foundation Trust 1,007
Large-scale testing (Phase 3)Study completedNCT00529087What this trial is testingStudy Evaluating Subcutaneous MOA-728 for the Treatment of Opioid-Induced Constipation (OIC) in Subjects With Chronic Non-Malignant PainWho this might be right forConstipation Bausch Health Americas, Inc. 460
Testing effectiveness (Phase 2)Study completedNCT01100151What this trial is testingALK37-003: A Study of RDC-1036 (ALKS 37) in Adults With Opioid-induced Constipation (OIC)Who this might be right forOpioid-induced Constipation Alkermes, Inc. 60
Post-approval studies (Phase 4)Study completedNCT05770960What this trial is testingColonic Motor Patterns in Healthy VolunteersWho this might be right forOpioid-Induced Constipation Universitaire Ziekenhuizen KU Leuven 15
Not applicableStudy completedNCT02813148What this trial is testingNaloxegol Drug Utilization Post Authorisation Safety StudyWho this might be right forOpioid Induced Constipation Kyowa Kirin Pharmaceutical Development Ltd 17,254
Large-scale testing (Phase 3)Study completedNCT04433390What this trial is testingEffect of Naloxegol on Postoperative Ileus in Patients Undergoing Cardiac SurgeryWho this might be right forPostoperative Ileus (Post Cardiac Surgery Constipation) CMC Ambroise Paré 305