Testing effectiveness (Phase 2)Study completedNCT04109118What this trial is testingBenzodiazepine Discontinuation in Opioid Agonist TherapyWho this might be right forSubstance Use Disorders Boston Medical Center 4
Testing effectiveness (Phase 2)Study completedNCT00000352What this trial is testingEffects of Dextromethorphan on Opioid Tolerance in Methadone Patients - 1Who this might be right forOpioid-Related DisordersSubstance-Related Disorders National Institute on Drug Abuse (NIDA)
Not applicableLooking for participantsNCT06488768What this trial is testingDuration of Peripheral Nerve Blocks in Opioid Tolerant Individuals - A Volunteer Blinded Matched Case-control StudyWho this might be right forNerve BlockOpioid Tolerance Charlotte Runge 40
Not applicableStudy completedNCT00275249What this trial is testingEvolution of Analgesic Tolerance With OpioidsWho this might be right forChronic Pain University of California, San Francisco 60
Post-approval studies (Phase 4)Study completedNCT01325493What this trial is testingLow Dose Ketamine Study on Opioid Tolerance and HyperalgesiaWho this might be right forIdiopathic ScoliosisSpondylolisthesis Julia Finkel 54
Testing effectiveness (Phase 2)Study completedNCT00000255What this trial is testingDifferential Acute Tolerance Development to Effects of Nitrous Oxide - 7Who this might be right forOpioid-Related DisordersSubstance-Related Disorders University of Chicago 10
Large-scale testing (Phase 3)Study completedNCT01556087What this trial is testingDistress Tolerance and BuprenorphineWho this might be right forOpioid Dependence Butler Hospital 59
Large-scale testing (Phase 3)Study completedNCT00737997What this trial is testingEffect of Early Morphine Administration on the Development of Acute Opioid Tolerance During Pediatric Scoliosis SurgeryWho this might be right forScoliosis The Hospital for Sick Children 40
Testing effectiveness (Phase 2)Study completedNCT00522587What this trial is testingSevoflurane-Remifentanil Interaction: Multiple Response Surfaces, Validation of Calibration Stimuli, Validation of the Intraoperative Isobole Concept and Investigating Remifentanil Induced Opioid ToleranceWho this might be right forAnesthesia University Hospital, Ghent 40
Early research (Phase 1)Ended earlyNCT00618397What this trial is testingPharmacokinetics of Low Dose Ketamine InfusionWho this might be right forSedationOpioid Tolerance University of Texas Southwestern Medical Center 5
Post-approval studies (Phase 4)Ended earlyNCT01103193What this trial is testingNitrous Oxide - Sevoflurane-Remifentanil InteractionWho this might be right forASA Class I/II Patients Scheduled for Surgery Under General Anesthesia University Hospital, Ghent 4
Large-scale testing (Phase 3)UnknownNCT01718496What this trial is testingMorphine, Dyspnea, Exercise and COPDWho this might be right forChronic Obstructive Pulmonary Disease McGill University Health Centre/Research Institute of the McGill University Health Centre 20
Not applicableEnded earlyNCT05250570What this trial is testingDistress Tolerance for Benzodiazepine DiscontinuationWho this might be right forSubstance Use Disorders University of Pittsburgh 1
Not applicableStudy completedNCT02602795What this trial is testingDistress Tolerance and HIV Prevention With XR-NTX Initiation in Opioid DependenceWho this might be right forOpiate DependenceSexually Transmitted DiseasesHIV Rhode Island Hospital 14
Not applicableStudy completedNCT05064592What this trial is testingRetrospective Study on Prolonged Sedation Effects With Inhaled Agents in PICUWho this might be right forMechanical Ventilation Assistance Publique - Hôpitaux de Paris 50
Post-approval studies (Phase 4)Ended earlyNCT01681264What this trial is testingEffect of Guanfacine on Opioid-induced Hyperalgesia (OIH) and ToleranceWho this might be right forChronic Pain Massachusetts General Hospital 200
Post-approval studies (Phase 4)Study completedNCT00246532What this trial is testingOpiate-Induced Tolerance & Hyperalgesia in Pain PatientsWho this might be right forChronic Low Back PainOpioid-induced Hyperalgesia National Institute of General Medical Sciences (NIGMS) 139
Testing effectiveness (Phase 2)UnknownNCT03824834What this trial is testingMorphine to Maximize the Benefits of Exercise Training in COPD or ILD and Persistent BreathlessnessWho this might be right forChronic Obstructive Pulmonary DiseaseInterstitial Lung Disease Dennis Jensen, Ph.D. 40
Not applicableUnknownNCT05276258What this trial is testingCryoablation of Intercostal Nerves for Post-Operative Pain Management in Opioid-Tolerant PatientsWho this might be right forPainPain, Postoperative The Methodist Hospital Research Institute 75
Testing effectiveness (Phase 2)Study completedNCT00000252What this trial is testingLack of Acute Tolerance Development to Effects of Nitrous Oxide - 4Who this might be right forOpioid-Related DisordersSubstance-Related Disorders University of Chicago 11