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Results for “Optic Atrophy, Hereditary, Leber”

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Showing 20 of 0 results

Not applicableActive Not RecruitingNCT03655223
What this trial is testing

Early Check: Expanded Screening in Newborns

Who this might be right for
Spinal Muscular AtrophyFragile X SyndromeFragile X - Premutation+182 more
RTI International 30,000
Not applicableLooking for participantsNCT01793168
What this trial is testing

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

Who this might be right for
Rare DisordersUndiagnosed DisordersDisorders of Unknown Prevalence+340 more
Sanford Health 20,000
Testing effectiveness (Phase 2)UnknownNCT02176733
What this trial is testing

Trial of Cyclosporine in the Acute Phase of Leber Hereditary Optic Neuropathy

Who this might be right for
Leber Hereditary Optic Neuropathy
University Hospital, Angers 12
Large-scale testing (Phase 3)Looking for participantsNCT04912843
What this trial is testing

Gene Therapy Clinical Trial for the Treatment Of Leber's HereDitary Optic Neuropathy

Who this might be right for
Leber's Hereditary Optic Neuropathy (LHON)
Wuhan Neurophth Biotechnology Limited Company 102
Not applicableStudy completedNCT02796274
What this trial is testing

Historical Case Record Survey of Visual Acuity Data From Patients With Leber's Hereditary Optic Neuropathy (LHON)

Who this might be right for
Leber's Hereditary Optic Neuropathy (LHON)
Santhera Pharmaceuticals 219
Large-scale testing (Phase 3)Looking for participantsNCT06891443
What this trial is testing

Study to Evaluate Sepofarsen in Subjects With Leber Congenital Amaurosis (LCA) Type 10 (HYPERION)

Who this might be right for
Leber Congenital Amaurosis 10BlindnessLeber Congenital Amaurosis+7 more
Laboratoires Thea 32
Large-scale testing (Phase 3)Active Not RecruitingNCT07406854
What this trial is testing

A Phase 3, Multicenter, Randomized, Double-Masked, Sham-Controlled Clinical Trial for Leber's Hereditary Optic Neuropathy (LHON) Associated With ND4 Mutation

Who this might be right for
Leber Hereditary Optic Neuropathy (LHON)
Wuhan Neurophth Biotechnology Limited Company 95
Not applicableStudy completedNCT03295071
What this trial is testing

REALITY LHON Registry

Who this might be right for
Leber Hereditary Optic Neuropathy
GenSight Biologics 44
Testing effectiveness (Phase 2)Ended earlyNCT02473445
What this trial is testing

A Long-term Extension of Study RP103-MITO-001 (NCT02023866) to Assess Cysteamine Bitartrate Delayed-release Capsules (RP103) in Children With Inherited Mitochondrial Disease

Who this might be right for
Mitochondrial Diseases
Amgen 22
Large-scale testing (Phase 3)UnknownNCT03153293
What this trial is testing

A Single Intravitreal Injection of rAAV2-ND4 for the Treatment of Leber's Hereditary Optic Neuropathy

Who this might be right for
Leber Hereditary Optic Neuropathy
Huazhong University of Science and Technology 159
Not applicableLooking for participantsNCT03011541
What this trial is testing

Stem Cell Ophthalmology Treatment Study II

Who this might be right for
Retinal DiseaseAge-Related Macular DegenerationRetinitis Pigmentosa+15 more
MD Stem Cells 500
Not applicableNo Longer AvailableNCT04381091
What this trial is testing

Expanded Access Program for Idebenone in Patients With Leber's Hereditary Optic Neuropathy Who Completed the LEROS Study

Who this might be right for
Leber's Hereditary Optic Neuropathy
Santhera Pharmaceuticals
Early research (Phase 1)Not Yet RecruitingNCT07258667
What this trial is testing

Pilot Study of the Efficacy of Nicotinamide (Vitamin B3) in Leber's Hereditary Optic Neuropathy

Who this might be right for
Leber Hereditary Optic Neuropathy (LHON)Leber's Hereditary Optic Neuropathy (LHON)Mitochondrial Disease+1 more
University Hospital, Angers 13
Testing effectiveness (Phase 2)Active Not RecruitingNCT05293626
What this trial is testing

Gene Therapy Clinical Trial for the Treatment of Leber's Hereditary Optic Neuropathy Associated With ND4 Mutations

Who this might be right for
Leber Hereditary Optic Neuropathy (LHON)
Neurophth Therapeutics Inc 12
Post-approval studies (Phase 4)Study completedNCT02774005
What this trial is testing

Study to Assess the Efficacy and Safety of Raxone in LHON Patients

Who this might be right for
Leber's Hereditary Optic Neuropathy (LHON)
Santhera Pharmaceuticals 199
Testing effectiveness (Phase 2)Study completedNCT03140969
What this trial is testing

Study to Evaluate QR-110 in Leber's Congenital Amaurosis (LCA) Due to the c.2991+1655A>G Mutation (p.Cys998X) in the CEP290 Gene

Who this might be right for
Leber's Congenital Amaurosis
Laboratoires Thea 11
Not applicableNo Longer AvailableNCT03672968
What this trial is testing

EAP_GS010_single Patient

Who this might be right for
Leber Hereditary Optic Neuropathy (Optic, Atrophy, Hereditary, Leber)
GenSight Biologics
Testing effectiveness (Phase 2)Study completedNCT02023866
What this trial is testing

Open-Label, Dose-Escalating Study Assessing Safety, Tolerability, Efficacy, of RP103 in Mitochondrial Disease

Who this might be right for
Inherited Mitochondrial Disease, Including Leigh Syndrome
Amgen 36
Large-scale testing (Phase 3)WithdrawnNCT01495715
What this trial is testing

Study With Idebenone in Patients With Chronic Vision Loss Due to Leber's Hereditary Optic Neuropathy (LHON)

Who this might be right for
Leber's Hereditary Optic Neuropathy
Santhera Pharmaceuticals
Large-scale testing (Phase 3)Study completedNCT04561466
What this trial is testing

Trial of Befizal® 200 mg for the Treatment of Leber Hereditary Optic Neuropathy

Who this might be right for
Safety IssuesEfficacy, Self
Hôpital Necker-Enfants Malades 14
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