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Results for “Oropharyngeal HPV-Positive Squamous Cell Carcinoma”

116 trials

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Showing 20 of 116 results

Testing effectiveness (Phase 2)Looking for participantsNCT06323460
What this trial is testing

Adaptive De-intensified Radiotherapy Using Circulating Tumor DNA in HPV- Associated Oropharyngeal Cancer

Who this might be right for
Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Oropharyngeal Squamous Cell Carcinoma
Ohio State University Comprehensive Cancer Center 45
Early research (Phase 1)Ended earlyNCT04301011
What this trial is testing

Study of TBio-6517 Given Alone or in Combination With Pembrolizumab in Solid Tumors

Who this might be right for
Solid TumorMicrosatellite Stable Colorectal CancerHPV Positive Oropharyngeal Squamous Cell Carcinoma+6 more
Turnstone Biologics, Corp. 27
Early research (Phase 1)Active Not RecruitingNCT04576091
What this trial is testing

Testing the Addition of an Anti-cancer Drug, BAY 1895344, With Radiation Therapy to the Usual Pembrolizumab Treatment for Recurrent Head and Neck Cancer

Who this might be right for
Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Recurrent Head and Neck Cutaneous Squamous Cell Carcinoma+29 more
National Cancer Institute (NCI)
Not applicableActive Not RecruitingNCT05814549
What this trial is testing

A Study Using Human Papillomavirus (HPV) DNA Testing to Detect HPV-Related Oropharyngeal Cancer (OPC)

Who this might be right for
Oropharyngeal CancerHPV-Related CarcinomaHPV Positive Oropharyngeal Squamous Cell Carcinoma
Memorial Sloan Kettering Cancer Center 9
Large-scale testing (Phase 3)Active Not RecruitingNCT05721755
What this trial is testing

Combining Radiation Therapy With Immunotherapy for the Treatment of Metastatic Squamous Cell Carcinoma of the Head and Neck

Who this might be right for
Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Metastatic Head and Neck Squamous Cell CarcinomaMetastatic Hypopharyngeal Squamous Cell Carcinoma+8 more
ECOG-ACRIN Cancer Research Group
Testing effectiveness (Phase 2)Study completedNCT04541355
What this trial is testing

Sodium Thiosulfate in Preventing Ototoxicity for Squamous Cell Cancer Patients Undergoing Chemoradiation With Cisplatin

Who this might be right for
Clinical Stage III Human Papillomavirus (HPV)-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Locally Advanced Head and Neck Squamous Cell Carcinoma+26 more
Hyunseok Kang, MD
Early research (Phase 1)Study completedNCT02113878
What this trial is testing

Phase Ib Study of BKM120 With Cisplatin and XRT in High Risk Locally Advanced Squamous Cell Cancer of Head and Neck

Who this might be right for
Carcinoma, Squamous Cell of Head and NeckHPV Positive Oropharyngeal Squamous Cell CarcinomaHypopharyngeal Cancer+3 more
Dana-Farber Cancer Institute 23
Early research (Phase 1)Looking for participantsNCT07156227
What this trial is testing

Testing the Addition of an Anti-Cancer Drug, Camonsertib, to Radiation Therapy for Recurrent Head and Neck Squamous Cell Carcinoma

Who this might be right for
Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Recurrent Head and Neck Squamous Cell CarcinomaRecurrent Hypopharyngeal Squamous Cell Carcinoma+27 more
National Cancer Institute (NCI)
Testing effectiveness (Phase 2)Looking for participantsNCT04900623
What this trial is testing

Risk-adapted Therapy in HPV+ Oropharyngeal Cancer Using Circulating Tumor (ct)HPV DNA Profile - The ReACT Study

Who this might be right for
HPV-Associated Oropharyngeal Squamous Cell CarcinomaHPV Positive Oropharyngeal Squamous Cell CarcinomaHPV-Mediated (P16-Positive) Oropharyngeal Carcinoma by AJCC V8 Stage+9 more
Jonathan Schoenfeld, MD, MPH 145
Large-scale testing (Phase 3)Active Not RecruitingNCT05063552
What this trial is testing

Testing the Use of Investigational Drugs Atezolizumab and/or Bevacizumab With or Without Standard Chemotherapy in the Second-Line Treatment of Advanced-Stage Head and Neck Cancers

Who this might be right for
Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Metastatic Head and Neck Squamous Cell CarcinomaMetastatic Hypopharyngeal Squamous Cell Carcinoma+20 more
National Cancer Institute (NCI)
Large-scale testing (Phase 3)Active Not RecruitingNCT04255849
What this trial is testing

Nine-valent HPV Vaccine to Prevent Persistent Oral HPV Infection in Men Living With HIV

Who this might be right for
HPV Positive Oropharyngeal Squamous Cell CarcinomaHIV-1-infectionHPV Infection
Weill Medical College of Cornell University 700
Not applicableStudy completedNCT01984359
What this trial is testing

HPV Serum DNA Levels Predicting Outcome in p16+ Squamous Cell Head and Neck Cancer

Who this might be right for
Subjects With p16 Positive/HPV Positive Squamous Cell Carcinomas of the Oropharynx
Abramson Cancer Center at Penn Medicine 80
Testing effectiveness (Phase 2)Looking for participantsNCT07172256
What this trial is testing

CUE-101with Pembrolizumab for Locally Advanced HPV+HNSCCs

Who this might be right for
Head and Neck Squamous Cell CarcinomaHPV Positive Oropharyngeal Squamous Cell CarcinomaNew Diagnosis Tumor+1 more
Yale University 30
Testing effectiveness (Phase 2)Looking for participantsNCT06532279
What this trial is testing

Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer

Who this might be right for
Clinical Stage I HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage II HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8+38 more
NRG Oncology
Not applicableStudy completedNCT01663259
What this trial is testing

Reduced-intensity Therapy for Oropharyngeal Cancer in Non-smoking HPV-16 Positive Patients

Who this might be right for
Squamous Cell Carcinoma of the OropharynxHPV
University of Michigan Rogel Cancer Center 43
Testing effectiveness (Phase 2)Active Not RecruitingNCT05714657
What this trial is testing

Shortened Course Adjuvant Radiotherapy Following TORS

Who this might be right for
HPV-Associated Oropharyngeal Squamous Cell Carcinoma
Abramson Cancer Center at Penn Medicine 104
Testing effectiveness (Phase 2)Study completedNCT04180215
What this trial is testing

A Phase 1/2 Study in Patients With HPV16+ Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma and Other Cancers

Who this might be right for
HPV-Related Squamous Cell Carcinoma
Hookipa Biotech GmbH 198
Testing effectiveness (Phase 2)Not Yet RecruitingNCT06759155
What this trial is testing

Phase II Clinical Trial of De-Intensified Therapy in Human Papilloma Virus (HPV) Associated Oropharyngeal Squamous Cell Carcinoma

Who this might be right for
OPSCCOropharyngeal Squamous Cell Carcinoma (SCC)HPV Associated Cancers
University of Vermont Medical Center 20
Early research (Phase 1)Study completedNCT02178072
What this trial is testing

Window Trial 5-aza in HNSCC, T-tare

Who this might be right for
Head and Neck Squamous Cell Carcinoma
Yale University 18
Not applicableLooking for participantsNCT06356272
What this trial is testing

Oropharynx (OPX) Biomarker Trial

Who this might be right for
Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8Metastatic Oropharyngeal Squamous Cell Carcinoma+8 more
Mayo Clinic 560
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