Early research (Phase 1)Study completedNCT00728689What this trial is testingPhase I Trial of an Investigational Small Pox MedicationWho this might be right forOrthopoxviral DiseaseSmallpoxMonkey Pox SIGA Technologies 12
Testing effectiveness (Phase 2)Study completedNCT00053482What this trial is testingDose Study of ACAM2000 Smallpox Vaccine in Previously Vaccinated AdultsWho this might be right forSmallpox Emergent BioSolutions 357
Not applicableStudy completedNCT00325975What this trial is testingImmune Responses to Smallpox VaccinationWho this might be right forSmallpox Vaccine National Institute of Allergy and Infectious Diseases (NIAID) 69
Large-scale testing (Phase 3)Study completedNCT05846243What this trial is testingStudy on Immunogenicity, Reactogenicity and Safety of the VACΔ6 Vaccine in Volunteers Aged 18-60 YearsWho this might be right forSmallpoxMonkeypoxCowpox+1 more Federal Budgetary Research Institution State Research Center of Virology and Biotechnology "Vector" 334
Early research (Phase 1)WithdrawnNCT00303225What this trial is testingSIGA-246 to Treat SmallpoxWho this might be right forVaccinia National Institute of Allergy and Infectious Diseases (NIAID)
Large-scale testing (Phase 3)Study completedNCT02474589What this trial is testingA Trial to Assess the Safety, Tolerability, and Pharmacokinetics of the Anti-Orthopoxvirus Compound TecovirimatWho this might be right forSmallpox SIGA Technologies 449
Large-scale testing (Phase 3)Study completedNCT02977715What this trial is testingJYNNEOS Smallpox Vaccine in Adult Healthcare Personnel at Risk for Mpox in the Democratic Republic of the CongoWho this might be right forMonkeypox Virus Infection Centers for Disease Control and Prevention 1,600
Early research (Phase 1)WithdrawnNCT00006630What this trial is testingVaccinia Immune Globulin in Treating or Preventing Vaccinal InfectionWho this might be right forHealthyCommunicable Diseases National Institute of Allergy and Infectious Diseases (NIAID)
Early research (Phase 1)Study completedNCT05762523What this trial is testingSafety and Tolerability Study of the VAC∆6 Vaccine in Volunteers Aged 18-40 YearsWho this might be right forSmallpoxMonkeypoxCowpox+1 more Federal Budgetary Research Institution State Research Center of Virology and Biotechnology "Vector" 60
Testing effectiveness (Phase 2)Study completedNCT00258947What this trial is testingEvaluation of Take and Safety of a Smallpox Vaccine in Healthy Young AdultsWho this might be right forSmallpoxPoxvirus Infection Sanofi 230
Testing effectiveness (Phase 2)Study completedNCT00907803What this trial is testingSafety, Tolerability, Pharmacokinetics (PK) of the Anti-Orthopox Drug, ST-246Who this might be right forOrthopoxviral Disease SIGA Technologies 107
Testing effectiveness (Phase 2)Looking for participantsNCT07379580What this trial is testingClinical Trial Investigating the Safety, Reactogenicity, and Immunogenicity After Immunization With an mRNA-based Mpox Vaccine Candidate in AfricaWho this might be right forMpox (Monkeypox)SmallpoxOrthopoxvirus Infection BioNTech SE 310
Testing effectiveness (Phase 2)Active Not RecruitingNCT06549530What this trial is testingOpen-label, Multicenter Immunogenicity and Safety Study of MVA-BN Vaccine in Children From 2 Years to Less Than 12 Years of Age Compared to Adults for the Prevention of Smallpox, Mpox, and Related Orthopoxvirus InfectionsWho this might be right forMonkeypox (Mpox) Bavarian Nordic 460