Crick
HomeTrialsGenesDrugs23andMeGraphBlogContact
  • Home
  • Trials
  • Genes
  • Drugs
  • 23andMe
  • Graph
  • Blog
  • Contact
Crick

An open-source clinical intelligence platform. Explore clinical trials, gene networks, and molecular structures using public data sources.

Data Sources

  • ClinicalTrials.gov
  • OpenTargets
  • ClinVar
  • PubChem

Links

  • Contact
  • About
  • Privacy

© 2026 Crick. All rights reserved.

Crick is for educational purposes only. Not medical advice.

Results for “Osteosarcoma, Recurrent, Refractory”

106 trials

Filters

Phase
Early Phase 1
Phase 1
Phase 2
Phase 3
Phase 4
Status
Recruiting
Active, Not Recruiting
Not Yet Recruiting
Completed
Enrolling by Invitation

Showing 20 of 106 results

Testing effectiveness (Phase 2)Study completedNCT02470091
What this trial is testing

Denosumab in Treating Patients With Recurrent or Refractory Osteosarcoma

Who this might be right for
Metastatic OsteosarcomaRecurrent OsteosarcomaRefractory Osteosarcoma+3 more
Children's Oncology Group 56
Testing effectiveness (Phase 2)Active Not RecruitingNCT03213652
What this trial is testing

Ensartinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With ALK or ROS1 Genomic Alterations (A Pediatric MATCH Treatment Trial)

Who this might be right for
Advanced Malignant Solid NeoplasmMalignant Solid NeoplasmRecurrent Ependymoma+30 more
National Cancer Institute (NCI) 13
Early research (Phase 1)Study completedNCT04661852
What this trial is testing

Cabozantinib With Topotecan-Cyclophosphamide

Who this might be right for
Relapsed Ewing SarcomaRefractory Ewing SarcomaRelapsed Osteosarcoma+1 more
Dana-Farber Cancer Institute 12
Testing effectiveness (Phase 2)Study completedNCT01614795
What this trial is testing

Cixutumumab and Temsirolimus in Treating Younger Patients With Recurrent or Refractory Sarcoma

Who this might be right for
Childhood Alveolar Soft Part SarcomaChildhood AngiosarcomaChildhood Epithelioid Sarcoma+12 more
National Cancer Institute (NCI) 46
Testing effectiveness (Phase 2)Study completedNCT00004078
What this trial is testing

Irinotecan in Treating Children With Refractory Solid Tumors

Who this might be right for
Childhood Central Nervous System Germ Cell TumorChildhood Choroid Plexus TumorChildhood Craniopharyngioma+18 more
Children's Oncology Group 181
Testing effectiveness (Phase 2)WithdrawnNCT02011126
What this trial is testing

Imetelstat Sodium in Treating Younger Patients With Relapsed or Refractory Solid Tumors

Who this might be right for
HepatoblastomaPreviously Treated Childhood RhabdomyosarcomaRecurrent Childhood Liver Cancer+5 more
Children's Oncology Group
Early research (Phase 1)Study completedNCT00119301
What this trial is testing

Methotrexate, Trimetrexate Glucuronate, and Leucovorin in Treating Patients With Refractory or Recurrent Osteosarcoma

Who this might be right for
Sarcoma
Memorial Sloan Kettering Cancer Center 18
Early research (Phase 1)Study completedNCT02644460
What this trial is testing

Abemaciclib in Children With DIPG or Recurrent/Refractory Solid Tumors

Who this might be right for
Diffuse Intrinsic Pontine GliomaBrain Tumor, RecurrentSolid Tumor, Recurrent+5 more
Emory University 53
Large-scale testing (Phase 3)Ended earlyNCT01987596
What this trial is testing

Study of Fixed vs. Flexible Filgrastim to Accelerate Bone Marrow Recovery After Chemotherapy in Children With Cancer

Who this might be right for
Childhood Choroid Plexus TumorChildhood MedulloblastomaChildhood Pineoblastoma+8 more
Barbara Ann Karmanos Cancer Institute 23
Not applicableWithdrawnNCT00378781
What this trial is testing

Heparin or M-EDTA in Preventing Catheter-Related Infections and Blockages in Patients at High Risk for a Catheter-Related Infection

Who this might be right for
Cancer
M.D. Anderson Cancer Center
Early research (Phase 1)Study completedNCT02085148
What this trial is testing

A Phase I Dose Finding Study in Children With Solid Tumors Recurrent or Refractory to Standard Therapy

Who this might be right for
Pediatric Oncology
Bayer 62
Testing effectiveness (Phase 2)WithdrawnNCT04791228
What this trial is testing

A Pilot Study of Thermodox and MR-HIFU for Treatment of Relapsed Solid Tumors

Who this might be right for
Solid TumorsSoft Tissue SarcomaEwing Sarcoma+6 more
Children's National Research Institute
Testing effectiveness (Phase 2)Looking for participantsNCT04851119
What this trial is testing

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

Who this might be right for
Colorectal CarcinomaEndometrial CarcinomaMelanoma+19 more
Children's Oncology Group 147
Testing effectiveness (Phase 2)Looking for participantsNCT04901702
What this trial is testing

Study of Onivyde With Talazoparib or Temozolomide in Children With Recurrent Solid Tumors and Ewing Sarcoma

Who this might be right for
Recurrent Solid TumorRecurrent Ewing SarcomaRecurrent Hepatoblastoma+19 more
St. Jude Children's Research Hospital 90
Testing effectiveness (Phase 2)Study completedNCT01962103
What this trial is testing

Study to Find a Safe Dose and Show Early Clinical Activity of Weekly Nab-paclitaxel in Pediatric Patients With Recurrent/ Refractory Solid Tumors

Who this might be right for
NeuroblastomaRhabdomyosarcomaEwing's Sarcoma+20 more
Celgene 107
Testing effectiveness (Phase 2)Study completedNCT03320330
What this trial is testing

Pepinemab in Treating Younger Patients With Recurrent, Relapsed, or Refractory Solid Tumors

Who this might be right for
Recurrent Malignant Solid NeoplasmRecurrent OsteosarcomaRefractory Malignant Solid Neoplasm+1 more
Children's Oncology Group 26
Testing effectiveness (Phase 2)Study completedNCT00070109
What this trial is testing

Trabectedin in Treating Young Patients With Recurrent or Refractory Soft Tissue Sarcoma or Ewing's Family of Tumors

Who this might be right for
Previously Treated Childhood RhabdomyosarcomaRecurrent Childhood RhabdomyosarcomaRecurrent Childhood Soft Tissue Sarcoma+2 more
Children's Oncology Group 50
Early research (Phase 1)Not Yet RecruitingNCT07211737
What this trial is testing

NKG2D.Zeta-NK Cell Conditioning With C7R.GD2.CAR-T Cells for Patients With Relapsed or Refractory Osteosarcoma or Neuroblastoma

Who this might be right for
Relapsed NeuroblastomaRefractory NeuroblastomaRelapsed Osteosarcoma+1 more
Baylor College of Medicine 27
Testing effectiveness (Phase 2)Study completedNCT00831844
What this trial is testing

Cixutumumab in Treating Patients With Relapsed or Refractory Solid Tumors

Who this might be right for
Adult RhabdomyosarcomaAdult Synovial SarcomaChildhood Hepatoblastoma+13 more
National Cancer Institute (NCI) 116
Testing effectiveness (Phase 2)Study completedNCT00030667
What this trial is testing

Imatinib Mesylate in Treating Patients With Relapsed or Refractory Solid Tumors of Childhood

Who this might be right for
Childhood Desmoplastic Small Round Cell TumorChildhood Synovial SarcomaGastrointestinal Stromal Tumor+5 more
National Cancer Institute (NCI) 100
Load More Results