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Results for “Ovarian Function Suppression”

26 trials

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Showing 20 of 26 results

Large-scale testing (Phase 3)Ended earlyNCT02532400
What this trial is testing

Neoadjuvant Aromatase Inhibitor(AI) With Ovarian Suppression Versus Chemotherapy in Premenopausal Breast Cancer Patients

Who this might be right for
Breast Cancer
Ruijin Hospital 21
Testing effectiveness (Phase 2)Looking for participantsNCT07158021
What this trial is testing

Leuprolide and Goserelin for Ovarian Function Suppression in Pre- or Peri-menopausal Women With Breast Cancer, OFS Trial

Who this might be right for
Anatomic Stage I Breast Cancer AJCC v8Anatomic Stage II Breast Cancer AJCC v8Anatomic Stage III Breast Cancer AJCC v8+2 more
University of Michigan Rogel Cancer Center 75
Large-scale testing (Phase 3)Study completedNCT00066690
What this trial is testing

Suppression of Ovarian Function With Either Tamoxifen or Exemestane Compared With Tamoxifen Alone in Treating Premenopausal Women With Hormone-Responsive Breast Cancer

Who this might be right for
Estrogen Receptor Positive Breast CancerProgesterone Receptor Positive TumorRecurrent Breast Carcinoma+5 more
ETOP IBCSG Partners Foundation 3,066
Large-scale testing (Phase 3)Looking for participantsNCT05879926
What this trial is testing

Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

Who this might be right for
Breast Cancer
NRG Oncology 3,960
Not applicableUnknownNCT05801705
What this trial is testing

Comparative Evaluation of Efficacy and Safety of Toremifene, Tamoxifen, and Aromatase Inhibitor Plus Ovarian Function Suppression in Hormone Receptor-Positive Early Breast Cancer Among Non-Low-Risk Premenopausal Women: A Real-World Study

Who this might be right for
Hormone-receptor-positive Breast CancerPremenopausal Breast CancerBreast Cancer Patients at Intermediate to High Risk+1 more
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University 700
Not applicableStudy completedNCT00128726
What this trial is testing

The Effects of Continuous Administration of a Monophasic Oral Contraceptive on Bleeding Days and Endometrial and Ovarian Function

Who this might be right for
Menstrual CycleHealthy
Milton S. Hershey Medical Center 62
Testing effectiveness (Phase 2)Looking for participantsNCT07159451
What this trial is testing

A Short-term Preoperative, Evaluating Activity and Safety of Elacestrant Monotherapy as Compared to Elacestrant + Ovarian Function Suppression (LHRH Agonist) in Premenopausal Patients With Stage I-II ER+/HER2- Breast Cancer

Who this might be right for
Breast Cancer
Gustave Roussy, Cancer Campus, Grand Paris 140
Not applicableNot Yet RecruitingNCT07311122
What this trial is testing

Endocrine Therapy Base on 21-gene RS

Who this might be right for
Breast Cancer
Gangnam Severance Hospital 4,000
Not applicableStudy completedNCT05122377
What this trial is testing

RWE About QOL and Compliance of Patients With OFS in China

Who this might be right for
Breast CancerQuality of LifeHormone Receptor-positive Breast Cancer
Fudan University 562
Post-approval studies (Phase 4)Looking for participantsNCT05333328
What this trial is testing

OFS in Premenopausal Node+ Breast Cancer With Low Genomic Risk

Who this might be right for
Breast CancerEstrogen Receptor Positive TumorHER2-negative Breast Cancer+2 more
Gangnam Severance Hospital 418
Large-scale testing (Phase 3)Study completedNCT00659373
What this trial is testing

Brain Function in Premenopausal Women Receiving Tamoxifen With or Without Ovarian Function Suppression for Early-Stage Breast Cancer on Clinical Trial IBCSG 24-02

Who this might be right for
Breast CancerFatigueSleep Disorders
ETOP IBCSG Partners Foundation 86
Testing effectiveness (Phase 2)Study completedNCT00429494
What this trial is testing

GnRH Analogue for Ovarian Function Preservation in Hematopoietic Stem Cell Transplantation Patients

Who this might be right for
AmenorrheaPremature Ovarian FailureOvarian Function Insufficiency
M.D. Anderson Cancer Center 60
Large-scale testing (Phase 3)UnknownNCT02132390
What this trial is testing

Adjuvant Toremifene With or Without Goserrelin in Premenopausal Women With Stage I-IIIA, Hormonal Receptor Positive Breast Cancer Accompanied With or Without Chemotherapy Induced Amenorrhoea

Who this might be right for
Breast CancerChemotherapy Induced AmenorrheaOvarian Function Suppression
Peking Union Medical College Hospital 300
Not applicableStudy completedNCT03112226
What this trial is testing

Effects of Ovarian Hormone Suppression on Vascular and Cognitive Function

Who this might be right for
Cognitive ImpairmentEstrogen DeficiencyMenopause+2 more
University of Colorado, Denver 19
Large-scale testing (Phase 3)UnknownNCT03664895
What this trial is testing

Density Lowering Effect of "OFS Add on to TMX"(DELFINO Trial)

Who this might be right for
Breast Cancer Invasive
Seoul National University Hospital 224
Not applicableStudy completedNCT03571841
What this trial is testing

Sexual Health and Rehabilitation After Ovarian Suppression Treatment

Who this might be right for
Breast Cancer SurvivorsSexual Function DisturbancesOvarian Suppression Treatment
Dana-Farber Cancer Institute 20
Not applicableLooking for participantsNCT06606535
What this trial is testing

ENDO-BRAIN: Effects of Endocrine Adjuvant Therapy with Aromatase Inhibitors on the Cognitive Function of Breast Cancer Patients

Who this might be right for
Cognitive Side Effects of Cancer TherapyHypoestrogenism
Ospedale Policlinico San Martino 60
Large-scale testing (Phase 3)UnknownNCT03137368
What this trial is testing

Evaluate Exemestane Tablets Combined With Ovarian Function Suppression/Ablation in Treatment of Premenopausal Breast Cancer Patients With CYP2D6*10 Mutations （STEP）

Who this might be right for
CYP2D6 Polymorphism
Cancer Institute and Hospital, Chinese Academy of Medical Sciences 300
Testing effectiveness (Phase 2)Study completedNCT02440230
What this trial is testing

Safety of OFS Combined With AI Endocrine Therapy in Chinese Premenopausal Breast Cancer Patients

Who this might be right for
Breast Cancer
Shanghai Jiao Tong University School of Medicine 110
Testing effectiveness (Phase 2)Looking for participantsNCT07460752
What this trial is testing

Evaluation of Alternative Site Goserelin Acetate Injection for Ovarian Function Suppression (OFS) in Local and Locally Advanced Premenopausal Hormone Receptor Positive Breast Cancer Patients

Who this might be right for
Anatomic Stage I Breast Cancer AJCC v8Anatomic Stage II Breast Cancer AJCC v8Anatomic Stage III Breast Cancer AJCC v8+1 more
Mayo Clinic 98
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