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Results for “P-glycoprotein”

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Showing 20 of 0 results

Early research (Phase 1)Study completedNCT06194214
What this trial is testing

A Drug Drug Interaction (DDI) Study of Pirtobrutinib (LOXO-305) and Digoxin (P-Glycoprotein Substrate) in Healthy Participants

Who this might be right for
Healthy
Eli Lilly and Company 16
Early research (Phase 1)Study completedNCT03089918
What this trial is testing

Investigate the Regional Brain Kinetics of Brain Drug Transporters Using P-glycoprotein and Breast Cancer Resistance Protein Substrates and by Using the Positron Emission Tomography Ligand 11C-JNJ-63779586 in the Human Brain

Who this might be right for
Alzheimer Disease
Janssen Research & Development, LLC 11
Not applicableStudy completedNCT00677885
What this trial is testing

P-glycoprotein Function in Brain Diseases

Who this might be right for
Alzheimer DiseaseParkinson DiseaseFrontotemporal Lobar Degeneration
National Institute of Mental Health (NIMH) 20
Early research (Phase 1)Study completedNCT03492437
What this trial is testing

Effect of Tepotinib on the PK of the P-gp Substrate Dabigatran Etexilate

Who this might be right for
Healthy
Merck KGaA, Darmstadt, Germany 20
Early research (Phase 1)Study completedNCT03782662
What this trial is testing

Learn About the Drug-drug Interactions of Sisunatovir in Healthy Adult Participants

Who this might be right for
Respiratory Syncytial Virus Infections
Pfizer 82
Early research (Phase 1)Study completedNCT00001302
What this trial is testing

A Phase I Study of Infusional Chemotherapy With the P-Glycoprotein Antagonist PSC 833

Who this might be right for
Breast CancerKidney NeoplasmLymphoma+2 more
National Cancer Institute (NCI) 80
Not applicableUnknownNCT02438072
What this trial is testing

Drug Metabolism and Antidepressant

Who this might be right for
Depression
University Hospital, Geneva 100
Early research (Phase 1)Looking for participantsNCT07744802
What this trial is testing

Evaluate the Effect of Vimseltinib on P-glycoprotein (P-gp) Inhibition in Healthy Male Participants

Who this might be right for
Healthy Male Participants
Deciphera Pharmaceuticals, LLC 20
Not applicableUnknownNCT05715658
What this trial is testing

Pharmacokinetic Study to Evaluate Dabigatran Etexilate in Elderly Subjects

Who this might be right for
Nonvalvular Atrial FibrillationHealth, Subjective
Dongyang Liu 36
Early research (Phase 1)Study completedNCT06677957
What this trial is testing

A Clinical Trial to Investigate the Clinical Drug-Drug Interaction of Divarasib With Probe Substrates of P-Glycoprotein and Breast Cancer Resistance Protein in Healthy Participants

Who this might be right for
Healthy Participants
Genentech, Inc. 19
Early research (Phase 1)Study completedNCT02182336
What this trial is testing

Effects of BI 201335 NA on Cytochrome P450 and P-glycoprotein Activity Using a Probe Drug Cocktail in Healthy Volunteers

Who this might be right for
Healthy
Boehringer Ingelheim 23
Testing effectiveness (Phase 2)Study completedNCT00071058
What this trial is testing

Surgery Plus Chemotherapy (Doxorubicin, Vincristine and Etoposide), Mitotane, and Tariquidar to Treat Adrenocortical Cancer

Who this might be right for
Adrenal Cortex Neoplasms
National Cancer Institute (NCI) 50
Early research (Phase 1)Study completedNCT03043248
What this trial is testing

TRK-700 Drug-Drug Interaction Study With Digoxin and Midazolam

Who this might be right for
Healthy
Toray Industries, Inc 48
Post-approval studies (Phase 4)Study completedNCT01112670
What this trial is testing

The Role of P-glycoprotein in Sitagliptin Clinical Pharmacology

Who this might be right for
Healthy
University of Colorado, Denver 33
Not applicableStudy completedNCT04383288
What this trial is testing

ABCB1/P-glycoprotein Expression Influence on Non-metastatic Osteosarcoma of the Extremities

Who this might be right for
Osteosarcoma
Grupo Espanol de Investigacion en Sarcomas 115
Post-approval studies (Phase 4)Study completedNCT00629122
What this trial is testing

Pharmacokinetics of Sublingual Versus Oral Tacrolimus in Patients Awaiting Kidney Transplantation

Who this might be right for
Kidney Failure, Chronic
Weill Medical College of Cornell University 5
Early research (Phase 1)Study completedNCT03011463
What this trial is testing

Pharmacokinetic Interaction Between Trospium With an Inhibitor of OCT1 and of P-gp in Subjects Genotyped for OCT1

Who this might be right for
PharmacokineticsInhibition EnzymeDrug Interaction Potentiation
Dr. R. Pfleger Chemische Fabrik GmbH 24
Early research (Phase 1)Study completedNCT02157558
What this trial is testing

An Open-Label Drug-Drug Interaction Study of Telotristat Etiprate and Fexofenadine in Healthy Subjects

Who this might be right for
Drug Interactions
Lexicon Pharmaceuticals 24
Not applicableUnknownNCT05532644
What this trial is testing

Correlation of P-glycoprotein Polymorphisms With Microbial Metabolites in Patients With Alzheimer's Disease on Medication

Who this might be right for
Alzheimer Disease
Aristotle University Of Thessaloniki 135
Testing effectiveness (Phase 2)Looking for participantsNCT05905887
What this trial is testing

Rivoceranib Plus Paclitaxel in Patients With Gastrointestinal Stromal Tumor

Who this might be right for
Gastrointestinal Stromal Tumors
Asan Medical Center 48
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