Not applicableEnrolling By InvitationNCT07703020What this trial is testingPrevalence and Determinants of Obesity in PKU PatientsWho this might be right forPhenylketonuria (PKU) Christel Tran 100
Post-approval studies (Phase 4)Study completedNCT01617070What this trial is testingEffects of Kuvan on Melatonin SecretionWho this might be right forPhenylketonuria (PKU) University of Southern California 10
Not applicableStudy completedNCT00909012What this trial is testingQuantitative Requirements of Docosahexaenoic Acid for Neural Function in Children With PhenylketonuriaWho this might be right forPhenylketonuria Ludwig-Maximilians - University of Munich 114
Not applicableStudy completedNCT04898829What this trial is testingEvaluation of PKU Explore FranceWho this might be right forPhenylketonurias Vitaflo International, Ltd 7
Very early researchStudy completedNCT05948020What this trial is testingEfficacy and Safety of Orally Administered Engineered Probiotics (CBT102-A) for the Treatment of Children With PhenylketonuriaWho this might be right forPhenylketonuria Children's Hospital of Fudan University 15
Testing effectiveness (Phase 2)Study completedNCT00924703What this trial is testingLong-Term Extension of Previous rAvPAL-PEG Protocols in Subjects With PKU (PAL-003)Who this might be right forPhenylketonuria BioMarin Pharmaceutical 68
Large-scale testing (Phase 3)Looking for participantsNCT06302348What this trial is testingSepiapterin in Participants With Phenylketonuria (PKU)Who this might be right forPhenylketonuria PTC Therapeutics 56
Not applicableStudy completedNCT03419819What this trial is testingEvaluation of PKU SphereWho this might be right forPhenylketonurias Vitaflo International, Ltd 28
Testing effectiveness (Phase 2)Study completedNCT00532844What this trial is testingA Phase 2, Pharmacokinetic (PK) Study of 6R-BH4 Alone or 6R-BH4 With Vitamin C in Subjects With Endothelial DysfunctionWho this might be right forEndothelial Dysfunction BioMarin Pharmaceutical 52
Not applicableStudy completedNCT05356377What this trial is testingPreliminary Study of Brain Effects of Palynziq-Related Changes in Phenylalanine in Individuals With PKUWho this might be right forPhenylketonurias University of Missouri-Columbia 6
Large-scale testing (Phase 3)Study completedNCT01732471What this trial is testingPhase 3 Open-label Study to Evaluate the Response and Safety of Kuvan® in Subjects With PhenylketonuriaWho this might be right forPhenylketonuria Merck KGaA, Darmstadt, Germany 90
Early research (Phase 1)WithdrawnNCT04014712What this trial is testingO2 Transport and Utilization in Health and Lung DiseaseWho this might be right forCOPDTetrahydrobiopterin DeficiencyOxidative Stress University of Massachusetts, Amherst
Post-approval studies (Phase 4)Study completedNCT01965912What this trial is testingKuvan®'s Effect on the Cognition of Children With PhenylketonuriaWho this might be right forPhenylketonuria BioMarin Pharmaceutical 34
Testing effectiveness (Phase 2)Study completedNCT01560286What this trial is testingEvaluate Subcutaneously Administered rAvPAL-PEG in Patients With Phenylketonuria for 24 WeeksWho this might be right forPhenylketonuria BioMarin Pharmaceutical 24
Large-scale testing (Phase 3)Active Not RecruitingNCT05270837What this trial is testingStudy to Evaluate the Safety and Efficacy of Pegvaliase in Adolescents (Ages 12-17) With PhenylketonuriaWho this might be right forPhenylketonuria (PKU) BioMarin Pharmaceutical 55
Not applicableEnded earlyNCT01904708What this trial is testingModerate Intensity Exercise and PhenylketonuriaWho this might be right forPhenylketonuriaPKU Oregon Health and Science University 2
Not applicableStudy completedNCT04943393What this trial is testingRemote Neurocognitive and Psychological Assessment in PKUWho this might be right forPhenylketonurias University of Missouri-Columbia 84
Post-approval studies (Phase 4)Active Not RecruitingNCT06780332What this trial is testingRapid Drug Desensitization Study in Adults Experiencing Hypersensitivity Reactions to PalynziqWho this might be right forPhenylketonuriaPKU BioMarin Pharmaceutical 9
Testing effectiveness (Phase 2)Study completedNCT03516487What this trial is testingSafety and Tolerability of SYNB1618 in Healthy Adult Volunteers and Adult Subjects With PhenylketonuriaWho this might be right forPhenylketonuriaHealthy Synlogic 70
Not applicableStudy completedNCT01847352What this trial is testingIron Status and Hypoxic Pulmonary Vascular ResponsesWho this might be right forLung HypoxiaPulmonary Arterial HypertensionIron Deficiency University of Oxford 31