Early research (Phase 1)Study completedNCT03521037What this trial is testingRucaparib Hepatic Impairment Study in Patients With a Solid TumorWho this might be right forNeoplasms pharmaand GmbH 16
Testing effectiveness (Phase 2)Active Not RecruitingNCT03212742What this trial is testingPhase I/IIa Study of Concomitant Radiotherapy With Olaparib and Temozolomide in Unresectable High Grade Gliomas PatientsWho this might be right forMalignant GliomasRadiotherapyPARP Inhibitor Centre Francois Baclesse 91
Testing effectiveness (Phase 2)Study completedNCT02354586What this trial is testingNiraparib in Patients With Ovarian Cancer Who Have Received Three or Four Previous Chemotherapy RegimensWho this might be right forOvarian NeoplasmsOvarian Cancer Tesaro, Inc. 463
Early research (Phase 1)Looking for participantsNCT05101551What this trial is testingStudy of Talazoparib in Combination With Chemotherapy in Relapsed Pediatric AML to Determine Safety and EfficacyWho this might be right forAcute Myeloid Leukemia Norman J. Lacayo 34
Early research (Phase 1)Study completedNCT01123876What this trial is testingEvaluating the Safety and Tolerability of the Poly-ADP Ribose (PARP) Inhibitor With FOLFIRI in Subjects With Solid TumorWho this might be right forGastric Cancer AbbVie (prior sponsor, Abbott) 60
Testing effectiveness (Phase 2)Active Not RecruitingNCT03830918What this trial is testingNiraparib, Temozolomide and Atezolizumab in Treating Patients With Advanced Solid Tumors and Extensive-Stage Small Cell Lung Cancer With a Complete or Partial Response to Platinum-Based First-Line ChemotherapyWho this might be right forAdvanced Malignant Solid NeoplasmExtensive Stage Lung Small Cell CarcinomaStage III Lung Cancer AJCC v8+6 more Jonsson Comprehensive Cancer Center 59
Testing effectiveness (Phase 2)Study completedNCT04740190What this trial is testingTalazoparib - Carboplatin for Recurrent High-grade Glioma With DDRdWho this might be right forRecurrent GliomaRecurrent GlioblastomaPoly ADP Ribose Polymerase (PARP) Inhibitor+2 more The University of Hong Kong 33
Early research (Phase 1)Study completedNCT02044120What this trial is testingESP1/SARC025 Global Collaboration: A Phase I Study of a Combination of the PARP Inhibitor, Niraparib and Temozolomide and/or Irinotecan Patients With Previously Treated, Incurable Ewing SarcomaWho this might be right forEwing Sarcoma Sarcoma Alliance for Research through Collaboration 34
Testing effectiveness (Phase 2)WithdrawnNCT01661868What this trial is testingOlaparib for Patients With Recurrent BRCA Deficient Ovarian CancerWho this might be right forOvarian CancerPeritoneal CancerFallopian Tube Cancer Dana-Farber Cancer Institute
Testing effectiveness (Phase 2)Looking for participantsNCT05797168What this trial is testingPhase I/IIa Study of AZD5335 as Monotherapy and Combination Therapy in Participants With Solid TumorsWho this might be right forOvarian CancerLung AdenocarcinomaEndometrial Cancer+1 more AstraZeneca 602
Testing effectiveness (Phase 2)Looking for participantsNCT05257993What this trial is testingStudy to Assess the Safety, Tolerability of JPI-547 in Combination With Modified FOLFIRINOX or Gemcitabine-nab-paclitaxel in Patients With Locally Advanced and Metastatic Pancreatic CancerWho this might be right forPancreatic Ductal Adenocarcinoma Onconic Therapeutics Inc. 71
Testing effectiveness (Phase 2)UnknownNCT04566952What this trial is testingAnlotinib Combined With Dose-reduced Olaparib in Patients With Platinum-Sensitive Recurrent Ovarian CancerWho this might be right forOvarian CancerOvarian and Fallopian Tube Cysts and NeoplasmsNeoplasms by Site+16 more Xiaoxiang Chen 68
Early research (Phase 1)Study completedNCT00387608What this trial is testingABT-888 in Patients With Refractory Solid Tumors or Hematologic CancerWho this might be right forLeukemiaLymphomaUnspecified Adult Solid Tumor, Protocol Specific National Institutes of Health Clinical Center (CC) 23
Testing effectiveness (Phase 2)Study completedNCT01063517What this trial is testingEfficacy Study of Olaparib With Paclitaxel Versus Paclitaxel in Gastric Cancer PatientsWho this might be right forGastric Cancer AstraZeneca 124
Early research (Phase 1)Study completedNCT02944396What this trial is testingStudy of Veliparib in Combination With Nivolumab and Platinum Doublet Chemotherapy in Participants With Metastatic or Advanced Non-Small Cell Lung Cancer (NSCLC)Who this might be right forNon-Small Cell Lung Cancer AbbVie 25
Not applicableStudy completedNCT04525183What this trial is testingREVITALIZE: A Telehealth Intervention for Women With Advanced Ovarian Cancer and PARP Inhibitor-Related FatigueWho this might be right forOvarian CancerFatigueCoping Behavior+1 more Dana-Farber Cancer Institute 49
Testing effectiveness (Phase 2)Study completedNCT05494580What this trial is testingPamiparib Plus Surufatinib in Patients With Platinum-resistant Ovarian CancerWho this might be right forOvarian CancerOvarian CarcinomaPlatinum-resistant Ovarian Cancer+2 more Sun Yat-sen University 29
Testing effectiveness (Phase 2)Looking for participantsNCT05759546What this trial is testingPARP Inhibitor With CDK4/6 Inhibitor and Endocrine Therapy in HR+/ HER2-Advanced Breast CancerWho this might be right forBreast Cancer Metastatic Fudan University 200
Early research (Phase 1)Study completedNCT01399840What this trial is testingStudy of BMN 673, a PARP Inhibitor, in Patients With Advanced Hematological MalignanciesWho this might be right forAcute Myeloid LeukemiaMyelodysplastic SyndromeChronic Lymphocytic Leukemia+1 more Pfizer 33
Early research (Phase 1)Study completedNCT00649207What this trial is testingA Phase I Study of ABT-888 in Combination With Conventional Whole Brain Radiation Therapy (WBRT) in Cancer Patients With Brain MetastasesWho this might be right forBrain DiseasesBrain NeoplasmsCentral Nervous System Diseases+2 more AbbVie (prior sponsor, Abbott) 80