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Results for “PARP”

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Showing 20 of 0 results

Early research (Phase 1)Study completedNCT02338622
What this trial is testing

Trial of Olaparib in Combination With AZD5363 (ComPAKT)

Who this might be right for
Advanced Cancer
Royal Marsden NHS Foundation Trust 60
Testing effectiveness (Phase 2)Active Not RecruitingNCT01638546
What this trial is testing

Temozolomide With or Without Veliparib in Treating Patients With Relapsed or Refractory Small Cell Lung Cancer

Who this might be right for
Recurrent Lung Small Cell Carcinoma
National Cancer Institute (NCI) 97
Testing effectiveness (Phase 2)Study completedNCT04826341
What this trial is testing

A Phase I/II Study of Sacituzumab Govitecan Plus Berzosertib in Small Cell Lung Cancer, Extra-Pulmonary Small Cell Neuroendocrine Cancer and Homologous Recombination-Deficient Cancers Resistant to PARP Inhibitors

Who this might be right for
HRD CancerSCLCAdvanced Solid Tumors
National Cancer Institute (NCI) 35
Testing effectiveness (Phase 2)Active Not RecruitingNCT03880019
What this trial is testing

A Phase II Clinical Trial Evaluating the Combination of Olaparib and Temozolomide for the Treatment of Advanced Uterine Leiomyosarcoma

Who this might be right for
Stage III Uterine Corpus Leiomyosarcoma AJCC v8Stage IV Uterine Corpus Leiomyosarcoma AJCC v8Uterine Corpus Leiomyosarcoma
National Cancer Institute (NCI) 23
Testing effectiveness (Phase 2)Looking for participantsNCT04716686
What this trial is testing

Niraparib Monotherapy as Maintain and Recurrent Treatment of Endometrial Serous Carcinoma

Who this might be right for
Endometrial CarcinomaSerous Carcinoma
Shandong University 83
Testing effectiveness (Phase 2)Ended earlyNCT02412371
What this trial is testing

A Study Evaluating the Efficacy and Tolerability of Veliparib in Combination With Paclitaxel/Carboplatin-Based Chemoradiotherapy Followed by Veliparib and Paclitaxel/Carboplatin Consolidation in Adults With Stage III Non-Small Cell Lung Cancer (NSCLC)

Who this might be right for
Non-small Cell Lung Cancer Stage III
AbbVie 48
Testing effectiveness (Phase 2)Study completedNCT05751629
What this trial is testing

Study to Evaluate the Safety and Efficacy of TSR-042, Bevacizumab, and Niraparib in Participants With Recurrent Ovarian Cancer

Who this might be right for
Ovarian Neoplasm
Tesaro, Inc. 41
Early research (Phase 1)Study completedNCT03057145
What this trial is testing

Combination Study of Prexasertib and Olaparib in Patients With Advanced Solid Tumors

Who this might be right for
Solid Tumor
Geoffrey Shapiro, MD, PhD 29
Testing effectiveness (Phase 2)Study completedNCT01583543
What this trial is testing

Olaparib in Adults With Recurrent/Metastatic Ewing's Sarcoma

Who this might be right for
Ewing's Sarcoma
Massachusetts General Hospital 12
Testing effectiveness (Phase 2)Looking for participantsNCT05704621
What this trial is testing

Secondary Cytoreductive Surgery (CRS) in Patients With Relapsed Ovarian Cancer Who Have Progressed on PARP Inhibitor Maintenance

Who this might be right for
Ovarian CancerDrug Related Neoplasm/Cancer
Korea University Guro Hospital 124
Testing effectiveness (Phase 2)Study completedNCT04174716
What this trial is testing

Basket Trial of IDX-1197, a PARP Inhibitor, in Patients With HRR Mutated Solid Tumors (VASTUS)

Who this might be right for
Solid TumorsHomologous Recombination Repair Gene MutationHomologous Recombination Deficiency
Idience Co., Ltd. 108
Large-scale testing (Phase 3)Study completedNCT02855944
What this trial is testing

ARIEL4: A Study of Rucaparib Versus Chemotherapy BRCA Mutant Ovarian, Fallopian Tube, or Primary Peritoneal Cancer Patients

Who this might be right for
Ovarian CancerEpithelial Ovarian CancerFallopian Tube Cancer+1 more
pharmaand GmbH 349
Testing effectiveness (Phase 2)WithdrawnNCT06365970
What this trial is testing

Niraparib and Dostarlimab for Patients With MMR-D/MSI-H Colorectal Cancers

Who this might be right for
MMR-D/MSI-H Colorectal Cancers
Ibrahim Halil Sahin
Not applicableLooking for participantsNCT06588322
What this trial is testing

Detection of Homologous Recombination Pathway Gene Mutations in Circulating Tumour DNA From BRCA-mutated Ovarian Cancer Patients Receiving First-line PARP Inhibitor Maintenance Therapy

Who this might be right for
Ovarian Cancer
Institut Claudius Regaud 130
Early research (Phase 1)Study completedNCT00994071
What this trial is testing

A Phase I Study of ABT-888, an Oral Inhibitor of Poly(ADP-ribose) Polymerase and Temozolomide in Children With Recurrent/Refractory CNS Tumors

Who this might be right for
MedulloblastomaPontine GliomaEpendymoma+2 more
National Cancer Institute (NCI) 9
Early research (Phase 1)Study completedNCT01589419
What this trial is testing

A Clinical Study Conducted in Multiple Centers Evaluating Escalating Doses of Veliparib in Combination With Capecitabine and Radiation in Patients With Locally Advanced Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer
AbbVie (prior sponsor, Abbott) 32
Testing effectiveness (Phase 2)Looking for participantsNCT06582628
What this trial is testing

Talazoparib Plus Enzalutamide After Progression to Abiraterone in Metastatic Prostate Cancer: (TEAM PC)

Who this might be right for
Metastatic Prostate Cancer
Fundacion Oncosur 78
Large-scale testing (Phase 3)Study completedNCT02000622
What this trial is testing

Assessment of the Efficacy and Safety of Olaparib Monotherapy Versus Physicians Choice Chemotherapy in the Treatment of Metastatic Breast Cancer Patients With Germline BRCA1/2 Mutations.

Who this might be right for
Breast Cancer MetastaticBRCA 1 Gene MutationBRCA 2 Gene Mutation
AstraZeneca 302
Not applicableUnknownNCT05310370
What this trial is testing

HRD and Resistance to PAPPi in EOC Patients

Who this might be right for
Epithelial Ovarian CancerHomologous Recombination DeficiencyHomologous Recombination Repair Gene Mutation+4 more
Lei Li 400
Testing effectiveness (Phase 2)Ended earlyNCT04972110
What this trial is testing

Study of RP-3500 (Camonsertib) With Niraparib or Olaparib in Advanced Solid Tumors

Who this might be right for
Advanced Solid Tumor, Adult
Repare Therapeutics 156
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