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Results for “PCSK1 Deficiency Obesity”

6 trials

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Showing 6 of 6 results

Not applicableStudy completedNCT03621007
What this trial is testing

An Observational,Prospective Natural History Study of Early-Onset Extreme Obesity Due to Bi-Allelic Loss-of-Function Mutations in the POMC, PCSK1 or LEPR Genes

Who this might be right for
POMC Deficiency ObesityPCSK1 Deficiency ObesityLEPR Deficiency Obesity
Rhythm Pharmaceuticals, Inc. 8
Large-scale testing (Phase 3)Study completedNCT02896192
What this trial is testing

Setmelanotide for the Treatment of Early-Onset Pro-Opiomelanocortin (POMC) Deficiency Obesity

Who this might be right for
Pro-opiomelanocortin (POMC) Deficiency Obesity
Rhythm Pharmaceuticals, Inc. 15
Large-scale testing (Phase 3)Study completedNCT04966741
What this trial is testing

Setmelanotide in Pediatric Participants With Rare Genetic Diseases of Obesity

Who this might be right for
Bardet-Biedl SyndromePOMC Deficiency ObesityPCSK1 Deficiency Obesity+1 more
Rhythm Pharmaceuticals, Inc. 12
Testing effectiveness (Phase 2)UnknownNCT05532020
What this trial is testing

An Open-Label Study of Diazoxide Choline in Patients With Genetic Obesities

Who this might be right for
SH2B1 Deficiency ObesityObesity Associated With PCSK1 Mutation (rs6232 Variant)SIM1 Deficiency Obesity
Soleno Therapeutics, Inc. 30
Not applicableActive Not RecruitingNCT06239064
What this trial is testing

Early Genetic Identification of Obesity

Who this might be right for
Obesity, ChildhoodHyperphagiaRetinopathy+5 more
Rolfs Consulting und Verwaltungs-GmbH (RCV) 1,000
Testing effectiveness (Phase 2)UnknownNCT06041841
What this trial is testing

Assess Efficacy and Safety of LB54640 in Patients With Genetic Obesity

Who this might be right for
POMC Deficiency ObesityPCSK1 Deficiency ObesityLEPR Deficiency Obesity
LG Chem 4