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Results for “PCSK9”

209 trials

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Showing 20 of 209 results

Large-scale testing (Phase 3)Study completedNCT01516879
What this trial is testing

Durable Effect of PCSK9 Antibody CompARed wiTh placEbo Study

Who this might be right for
Hypercholesterolemia
Amgen 905
Large-scale testing (Phase 3)Study completedNCT04031742
What this trial is testing

Evaluate Safety and Efficacy of IBI306, a PCSK9 Monoclonal Antibody in Chinese Subjects With Homozygous Familial Hypercholesterolemia

Who this might be right for
Homozygous Familial Hypercholesterolemia
Innovent Biologics (Suzhou) Co. Ltd. 18
Early research (Phase 1)Ended earlyNCT01350960
What this trial is testing

Multiple Ascending Dose Study of SPC5001 in Treatment of Healthy Subjects and Subjects With FH

Who this might be right for
Hypercholesterolemia
Santaris Pharma A/S 24
Not applicableLooking for participantsNCT05994274
What this trial is testing

A Clinical Study of Association Between Postoperative Dyslipidemia and Organ Rejection in Transplant Patients

Who this might be right for
Heart Transplant Failure and Rejection
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology 80
Testing effectiveness (Phase 2)UnknownNCT06304987
What this trial is testing

Neoadjuvant Chemoradiotherapy Combined With PD-1 Inhibitor and PCSK9 Inhibitor for pMMR/MSS Locally Advanced Mid-low Rectal Cancer

Who this might be right for
Locally Advanced Rectal Cancer
Beijing Friendship Hospital 50
Large-scale testing (Phase 3)Not Yet RecruitingNCT07119918
What this trial is testing

PCSK9 Inhibitor for Intracranial Atherosclerotic Symptomatic Stenosis

Who this might be right for
Symptomatic Intracranial Atherosclerotic Stenosis
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University 5,276
Large-scale testing (Phase 3)Study completedNCT07295418
What this trial is testing

SAL003 in Participants With Hypercholesterolemia and Mixed Dyslipidemia

Who this might be right for
Hyperlipidemias
Shenzhen Salubris Pharmaceuticals Co., Ltd. 618
Large-scale testing (Phase 3)Study completedNCT05952869
What this trial is testing

Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) in Adults With Heterozygous Familial Hypercholesterolemia (MK-0616-017/CORALreef HeFH)

Who this might be right for
HypercholesterolemiaFamilial Hypercholesterolemia
Merck Sharp & Dohme LLC 303
Large-scale testing (Phase 3)UnknownNCT04759534
What this trial is testing

Application of PCSK9 Inhibitors in Patients With Heterozygous Familial Hypercholesterolemia

Who this might be right for
Efficacy and SafetyHeterozygous Familial HypercholesterolemiaPCSK9
Shenzhen People's Hospital 20
Testing effectiveness (Phase 2)Not Yet RecruitingNCT07014215
What this trial is testing

PD-1 Combined With Bevacizumab and PCSK-9 Inhibitor in Patients With Advanced NSCLC Who Have Progressed After Anti- PD- 1/L1 Therapy

Who this might be right for
NSCLC (Advanced Non-small Cell Lung Cancer)Resistance to Immunotherapy
Anhui Provincial Cancer Hospital 52
Testing effectiveness (Phase 2)Active Not RecruitingNCT05001984
What this trial is testing

Trial of PCSK9 Inhibition in Patients with Acute Stroke and Symptomatic Intracranial Atherosclerosis

Who this might be right for
Intracranial AtherosclerosisAcute Ischemic StrokeICAS - Intracranial Atherosclerosis
Chang Gung Memorial Hospital 60
Large-scale testing (Phase 3)Study completedNCT01763905
What this trial is testing

Goal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects -2

Who this might be right for
Hyperlipidemia
Amgen 307
Large-scale testing (Phase 3)UnknownNCT03634293
What this trial is testing

Treatment of Severe Infection With Antihyperlipidemia Drug

Who this might be right for
SepsisSeptic Shock
Wolfson Medical Center 712
Post-approval studies (Phase 4)Study completedNCT05192941
What this trial is testing

Study of Efficacy, Safety, Tolerability and Quality of Life of Inclisiran (KJX839) vs Placebo, on Top of Ongoing Individually Optimized Lipid-lowering Therapy, in Participants With Hypercholesterolemia

Who this might be right for
Hypercholesterolemia
Novartis Pharmaceuticals 1,770
Not applicableStudy completedNCT00847782
What this trial is testing

An Experimental Medicine Study to Evaluate Serum Biomarkers of Lipid Metabolism

Who this might be right for
Atherosclerosis
Bristol-Myers Squibb 150
Testing effectiveness (Phase 2)UnknownNCT03869073
What this trial is testing

Evolocumab for PCSK9 Lowering in Early Acute Sepsis (The PLEASe Study)

Who this might be right for
Sepsis
University of British Columbia 36
Large-scale testing (Phase 3)Study completedNCT05888103
What this trial is testing

Efficacy and Safety of Inclisiran as Monotherapy in Chinese Adults With Low or Moderate ASCVD Risk and Elevated Low-density Lipoprotein Cholesterol.

Who this might be right for
Primary Hypercholesterolemia or Mixed Dyslipidemia
Novartis Pharmaceuticals 207
Testing effectiveness (Phase 2)Active Not RecruitingNCT05553834
What this trial is testing

PCSK9 Inhibitor and PD-1 Inhibitor in Patients With Metastatic, Refractory To Prior Anti PD-1 Non-small Cell Lung

Who this might be right for
Non-small Cell Lung Cancer (NSCLC)
Duke University 60
Post-approval studies (Phase 4)UnknownNCT03811223
What this trial is testing

Effects of Evolocumab Versus Placebo Added to Standard Lipid-lowering Therapy on Fasting and Post Fat Load Lipids in Patients With Familial Dysbetalipoproteinemia

Who this might be right for
Familial DysbetalipoproteinemiaHyperlipoproteinemia Type III
UMC Utrecht 30
Post-approval studies (Phase 4)UnknownNCT04397653
What this trial is testing

Evolocumab Plus Ezetimibe in High Risk Haemodialized Statin Intolerant Patients

Who this might be right for
HypercholesterolemiaChronic Kidney Disease Requiring Chronic Dialysis
Policlinico Casilino ASL RMB 50
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